General Information of the Compound
Compound ID
CP0502923
Compound Name
4-bromo-1-ethoxy-N-[2-(4-pyridin-2-ylpiperazin-1-yl)ethyl]naphthalene-2-carboxamide
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Structure
Formula
C24H27BrN4O2
Molecular Weight
483.41
Canonical SMILES
CCOc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccn1
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InChI
InChI=1S/C24H27BrN4O2/c1-2-31-23-19-8-4-3-7-18(19)21(25)17-20(23)24(30)27-11-12-28-13-15-29(16-14-28)22-9-5-6-10-26-22/h3-10,17H,2,11-16H2,1H3,(H,27,30)
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InChIKey
IRUKZAGWAZWZBI-UHFFFAOYSA-N
Physicochemical Property
logP
3.948
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
57.7
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 15232481
ChEMBL ID
CHEMBL169450
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 79.43 nM
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