General Information of the Compound
Compound ID
CP0916146
Compound Name
2-(6-Methoxy-naphthalen-2-yl)-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-propionamide oxalic acid
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Structure
Formula
C30H37N3O7
Molecular Weight
551.64
Canonical SMILES
COc1ccc2cc([C@H](C)C(=O)NCCCN3CCN(c4ccccc4OC)CC3)ccc2c1.O=C(O)C(=O)O
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InChI
InChI=1S/C28H35N3O3.C2H2O4/c1-21(22-9-10-24-20-25(33-2)12-11-23(24)19-22)28(32)29-13-6-14-30-15-17-31(18-16-30)26-7-4-5-8-27(26)34-3;3-1(4)2(5)6/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,29,32);(H,3,4)(H,5,6)/t21-;/m0./s1
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InChIKey
XMTZXXGGLDZXRN-BOXHHOBZSA-N
Physicochemical Property
logP
3.4446
Rotatable Bonds
9
Heavy Atom Count
40
Polar Areas
128.64
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44350714
ChEMBL ID
CHEMBL126331
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 94.6 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 262 nM
   TI
   LI
   LO
   TS