General Information of the Compound
Compound ID
CP0377876
Compound Name
[(3aS,9bS)-3-[4-[(4-phenylbenzoyl)amino]butyl]-1,2,3a,4,5,9b-hexahydrobenzo[e]indol-7-yl] methanesulfonate
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Structure
Formula
C30H34N2O4S
Molecular Weight
518.679
Canonical SMILES
CS(=O)(=O)Oc1ccc2[C@@H]3CCN(CCCCNC(=O)c4ccc(cc4)-c4ccccc4)[C@H]3CCc2c1
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InChI
InChI=1S/C30H34N2O4S/c1-37(34,35)36-26-14-15-27-25(21-26)13-16-29-28(27)17-20-32(29)19-6-5-18-31-30(33)24-11-9-23(10-12-24)22-7-3-2-4-8-22/h2-4,7-12,14-15,21,28-29H,5-6,13,16-20H2,1H3,(H,31,33)/t28-,29-/m0/s1
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InChIKey
TWPGFOWTCCVBGS-VMPREFPWSA-N
Physicochemical Property
logP
5.0063
Rotatable Bonds
9
Heavy Atom Count
37
Polar Areas
75.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44329126
ChEMBL ID
CHEMBL329702
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 50.12 nM
   TI
   LI
   LO
   TS