General Information of the Compound
Compound ID
CP0315215
Compound Name
1-[(3,4-dichlorophenyl)methyl]-3-[2-(1,3-dihydroisoindol-2-yl)ethyl]imidazolidin-2-one
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Structure
Formula
C20H21Cl2N3O
Molecular Weight
390.314
Canonical SMILES
Clc1ccc(CN2CCN(CCN3Cc4ccccc4C3)C2=O)cc1Cl
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InChI
InChI=1S/C20H21Cl2N3O/c21-18-6-5-15(11-19(18)22)12-25-10-9-24(20(25)26)8-7-23-13-16-3-1-2-4-17(16)14-23/h1-6,11H,7-10,12-14H2
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InChIKey
OJGCUCNESMAFSG-UHFFFAOYSA-N
Physicochemical Property
logP
4.2468
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
26.79
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 45267261
ChEMBL ID
CHEMBL560650
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 79.43 nM
   TI
   LI
   LO
   TS