General Information of the Compound
Compound ID
CP0517139
Compound Name
[(4aS,10bS)-4-[4-[(4-phenylbenzoyl)amino]butyl]-2,3,4a,5,6,10b-hexahydro-1H-benzo[f]quinolin-8-yl] methanesulfonate
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Structure
Formula
C31H36N2O4S
Molecular Weight
532.706
Canonical SMILES
CS(=O)(=O)Oc1ccc2[C@@H]3CCCN(CCCCNC(=O)c4ccc(cc4)-c4ccccc4)[C@H]3CCc2c1
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InChI
InChI=1S/C31H36N2O4S/c1-38(35,36)37-27-16-17-28-26(22-27)15-18-30-29(28)10-7-21-33(30)20-6-5-19-32-31(34)25-13-11-24(12-14-25)23-8-3-2-4-9-23/h2-4,8-9,11-14,16-17,22,29-30H,5-7,10,15,18-21H2,1H3,(H,32,34)/t29-,30-/m0/s1
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InChIKey
QCZONXSWEXKHJH-KYJUHHDHSA-N
Physicochemical Property
logP
5.3964
Rotatable Bonds
9
Heavy Atom Count
38
Polar Areas
75.71
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44329046
ChEMBL ID
CHEMBL97440
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS