General Information of the Compound
Compound ID
CP0081044
Compound Name
N-[4-[[5-(cyclopropylmethoxy)-1,2,3,4-tetrahydronaphthalen-2-yl]-propylamino]butyl]-4-phenylbenzamide
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Structure
Formula
C34H42N2O2
Molecular Weight
510.722
Canonical SMILES
CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)C1CCc2c(C1)cccc2OCC1CC1
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InChI
InChI=1S/C34H42N2O2/c1-2-22-36(31-19-20-32-30(24-31)11-8-12-33(32)38-25-26-13-14-26)23-7-6-21-35-34(37)29-17-15-28(16-18-29)27-9-4-3-5-10-27/h3-5,8-12,15-18,26,31H,2,6-7,13-14,19-25H2,1H3,(H,35,37)
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InChIKey
UUKCJRIPKQWEID-UHFFFAOYSA-N
Physicochemical Property
logP
6.9219
Rotatable Bonds
13
Heavy Atom Count
38
Polar Areas
41.57
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10075078
SID: 15060561
ChEMBL ID
CHEMBL61444
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 794.33 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2.512 nM
   TI
   LI
   LO
   TS