General Information of the Compound
Compound ID
CP0426179
Compound Name
CHEMBL4761274
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Formula
C23H35ClN2O
Molecular Weight
390.999
Canonical SMILES
CCCC(=O)N[C@H]1CC[C@H](CCN2CCc3ccc(Cl)cc3[C@@H](C)C2)CC1
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InChI
InChI=1S/C23H35ClN2O/c1-3-4-23(27)25-21-9-5-18(6-10-21)11-13-26-14-12-19-7-8-20(24)15-22(19)17(2)16-26/h7-8,15,17-18,21H,3-6,9-14,16H2,1-2H3,(H,25,27)/t17-,18-,21-/m0/s1
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InChIKey
WZEVFJPWWRPRRO-WFXMLNOXSA-N
Physicochemical Property
logP
5.1668
Rotatable Bonds
6
Heavy Atom Count
27
Polar Areas
32.34
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4761274
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 84 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 8.1 nM
   TI
   LI
   LO
   TS