General Information of the Compound
| Compound ID |
CP0033479
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| Compound Name |
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
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| Synonyms |
Aminasine
Aminazin
Aminazine
Ampliactil
Amplicitil
Amplictil
BC 135
Chlor-PZ
Chlor-Promanyl
Chlordelazine
Chlorderazin
Chloropromazine
Chlorpromados
Chlorpromanyl (discontinued)
Chlorpromazin
Chlorpromazine
Chlorpromazine (USP/INN)
Chlorpromazine Tannate
Chlorpromazine [USAN:INN:BAN]
Chlorpromazinum
Chlorpromazinum [INN-Latin]
Clorpromazina
Clorpromazina [INN-Spanish]
Clorpromazina [Italian]
Contomin
Cromedazine
Elmarin
Esmind
Fenactil
Fenaktyl
Fraction AB
HL 5746
JHICC02042
Largactil
Largactil (TN)
Largactil Liquid
Largactil Oral Drops
Largactilothiazine
Largactyl
Megaphen
Novo-Chlorpromazine
Novomazina
Phenactyl
Phenathyl
Phenothiazine hydrochloride
Plegomasine
Plegomazin
Prazilpromactil
Proma
Promactil
Promazil
Propaphen
Propaphenin
Prozil
Psychozine
SKF 2601-A
SKF 2601A
SKF-2601
Sanopron
Thorazine
Thorazine (TN)
Thorazine Spansule
Thorazine Suppositories
Thorazine hydrochloride
Torazina
Wintermin
Z80
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| Structure |
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| Formula |
C17H19ClN2S
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| Molecular Weight |
318.873
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| Canonical SMILES |
CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
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| InChI |
InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3
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| InChIKey |
ZPEIMTDSQAKGNT-UHFFFAOYSA-N
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| CAS |
34468-21-8
50-53-3
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT01019, 5-hydroxytryptamine receptor 2B
Protein ID: PT00939, 5-hydroxytryptamine receptor 2C
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Protein ID: PT00941, 5-hydroxytryptamine receptor 7
Protein ID: PT04542, Bile salt export pump
Protein ID: PT01195, D(1A) dopamine receptor
Protein ID: PT01169, D(1B) dopamine receptor
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Protein ID: PT00957, D(2) dopamine receptor
Protein ID: PT00943, D(3) dopamine receptor
Protein ID: PT01161, D(4) dopamine receptor
Protein ID: PT06109, Geminin
Protein ID: PT01206, Histamine H1 receptor
Protein ID: PT01194, Histamine H3 receptor
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT02591, Major prion protein
Protein ID: PT01310, Muscarinic acetylcholine receptor M1
Protein ID: PT01156, Muscarinic acetylcholine receptor M4
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT00871, Sodium-dependent serotonin transporter
Protein ID: PT03795, Solute carrier family 22 member 1
Protein ID: PT01914, Transient receptor potential cation channel subfamily V member 1
Clinical Information about the Compound
Drug 1 ( Chlorpromazine )
| Drug Name | Chlorpromazine | ||
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| Company | GlaxoSmithKline | ||
| Indication | |||
| Target(s) |
Dopamine D2 receptor (D2R)
Antagonist
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