Brief Information of the Compound and Protein
Compound Name
(chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-amine
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PubChem ID
CID: 2726
SID: 14923746
Canonical SMILES
CN(C)CCCN1c2ccccc2Sc2ccc(Cl)cc12
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Compound Formula C17H19ClN2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 2A
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P28223
Gene Name
HTR2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 6.31 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 12.02 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.4 nM