General Information of the Compound
Compound ID
CP0383909
Compound Name
2-[4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]phenyl]sulfonyl-3,4-dihydro-1H-isoquinoline
    Show/Hide
Structure
Formula
C33H37N3O3S
Molecular Weight
555.744
Canonical SMILES
COc1ccc(cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1)S(=O)(=O)N1CCc2ccccc2C1
    Show/Hide
InChI
InChI=1S/C33H37N3O3S/c1-39-33-18-16-29(40(37,38)36-21-19-25-10-7-8-13-27(25)23-36)22-30(33)31-17-15-28(34-31)24-35-20-9-3-6-14-32(35)26-11-4-2-5-12-26/h2,4-5,7-8,10-13,15-18,22,32,34H,3,6,9,14,19-21,23-24H2,1H3
    Show/Hide
InChIKey
FXOJKPLALHHTKM-UHFFFAOYSA-N
Physicochemical Property
logP
6.5546
Rotatable Bonds
7
Heavy Atom Count
40
Polar Areas
65.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44363213
ChEMBL ID
CHEMBL356526
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.995 nM
   TI
   LI
   LO
   TS