General Information of the Compound
Compound ID
CP0460919
Compound Name
CHEMBL3084596
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Formula
C30H38ClN3O4S
Molecular Weight
572.171
Canonical SMILES
Cl.CS(=O)(=O)Oc1ccc2CCN(CC[C@H]3CC[C@@H](CC3)NC(=O)c3cccc(c3)-n3cccc3)CCc2c1
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InChI
InChI=1S/C30H37N3O4S.ClH/c1-38(35,36)37-29-12-9-24-14-19-32(20-15-25(24)22-29)18-13-23-7-10-27(11-8-23)31-30(34)26-5-4-6-28(21-26)33-16-2-3-17-33;/h2-6,9,12,16-17,21-23,27H,7-8,10-11,13-15,18-20H2,1H3,(H,31,34);1H/t23-,27-;
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InChIKey
GHZSMFQVDZLPEQ-DWAHYBIUSA-N
Physicochemical Property
logP
5.017
Rotatable Bonds
8
Heavy Atom Count
39
Polar Areas
80.64
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL3084596
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 251.19 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.162 nM
   TI
   LI
   LO
   TS