General Information of the Compound
Compound ID
CP0534109
Compound Name
[3-methyl-1-(3-oxo-3-phenylpropyl)-4-phenylpiperidin-4-yl] propanoate
    Show/Hide
Structure
Formula
C24H29NO3
Molecular Weight
379.5
Canonical SMILES
CCC(=O)OC1(CCN(CCC(=O)c2ccccc2)CC1C)c1ccccc1
    Show/Hide
InChI
InChI=1S/C24H29NO3/c1-3-23(27)28-24(21-12-8-5-9-13-21)15-17-25(18-19(24)2)16-14-22(26)20-10-6-4-7-11-20/h4-13,19H,3,14-18H2,1-2H3
    Show/Hide
InChIKey
MZORJBGOVRTVQW-UHFFFAOYSA-N
Physicochemical Property
logP
4.4499
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
46.61
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 424721
ChEMBL ID
CHEMBL136161
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10000 nM
   TI
   LI
   LO
   TS