General Information of the Compound
Compound ID
CP0442129
Compound Name
(3-{4-[1-((E)-4-{2-[4-(3-Cyclohexyl-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-diethyl-amine
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Structure
Formula
C46H55N5O2
Molecular Weight
709.979
Canonical SMILES
CCN(CC)CCCOc1ccc(cc1)-c1nc2ccccc2n1C\C=C\Cn1c(nc2ccccc12)-c1ccc(OCCCC2CCCCC2)cc1
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InChI
InChI=1S/C46H55N5O2/c1-3-49(4-2)31-15-35-53-40-29-25-38(26-30-40)46-48-42-20-9-11-22-44(42)51(46)33-13-12-32-50-43-21-10-8-19-41(43)47-45(50)37-23-27-39(28-24-37)52-34-14-18-36-16-6-5-7-17-36/h8-13,19-30,36H,3-7,14-18,31-35H2,1-2H3/b13-12+
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InChIKey
INHFSVLNFMQBGJ-OUKQBFOZSA-N
Physicochemical Property
logP
10.8264
Rotatable Bonds
18
Heavy Atom Count
53
Polar Areas
57.34
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
53

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44319612
ChEMBL ID
CHEMBL316014
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1027 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 39 nM
   TI
   LI
   LO
   TS