General Information of the Compound
Compound ID
CP0505181
Compound Name
(3-{4-[1-((E)-4-{2-[4-(3-Dipropylamino-propoxy)-phenyl]-benzoimidazol-1-yl}-but-2-enyl)-1H-benzoimidazol-2-yl]-phenoxy}-propyl)-dipropyl-amine
    Show/Hide
Structure
Formula
C48H62N6O2
Molecular Weight
755.064
Canonical SMILES
CCCN(CCC)CCCOc1ccc(cc1)-c1nc2ccccc2n1C\C=C\Cn1c(nc2ccccc12)-c1ccc(OCCCN(CCC)CCC)cc1
    Show/Hide
InChI
InChI=1S/C48H62N6O2/c1-5-29-51(30-6-2)33-15-37-55-41-25-21-39(22-26-41)47-49-43-17-9-11-19-45(43)53(47)35-13-14-36-54-46-20-12-10-18-44(46)50-48(54)40-23-27-42(28-24-40)56-38-16-34-52(31-7-3)32-8-4/h9-14,17-28H,5-8,15-16,29-38H2,1-4H3/b14-13+
    Show/Hide
InChIKey
IKMVUGGIEHIWKD-BUHFOSPRSA-N
Physicochemical Property
logP
10.7582
Rotatable Bonds
24
Heavy Atom Count
56
Polar Areas
60.58
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
8
Complexity
56

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 10395316
SID: 15410941
ChEMBL ID
CHEMBL315137
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 343 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 5 nM
   TI
   LI
   LO
   TS