General Information of the Compound
Compound ID
CP0383964
Compound Name
(2R)-5-methoxy-6-(2-phenylethyl)-N,N-dipropyl-1,2,3,4-tetrahydronaphthalen-2-amine
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Structure
Formula
C25H35NO
Molecular Weight
365.561
Canonical SMILES
CCCN(CCC)[C@@H]1CCc2c(C1)ccc(CCc1ccccc1)c2OC
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InChI
InChI=1S/C25H35NO/c1-4-17-26(18-5-2)23-15-16-24-22(19-23)14-13-21(25(24)27-3)12-11-20-9-7-6-8-10-20/h6-10,13-14,23H,4-5,11-12,15-19H2,1-3H3/t23-/m1/s1
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InChIKey
YFMHFOQRZFIVPU-HSZRJFAPSA-N
Physicochemical Property
logP
5.4597
Rotatable Bonds
9
Heavy Atom Count
27
Polar Areas
12.47
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44353479
ChEMBL ID
CHEMBL132930
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 19.95 nM
   TI
   LI
   LO
   TS