General Information of the Compound
Compound ID
CP0502763
Compound Name
phenyl 4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]benzenesulfonate
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Structure
Formula
C30H32N2O4S
Molecular Weight
516.663
Canonical SMILES
COc1ccc(cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1)S(=O)(=O)Oc1ccccc1
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InChI
InChI=1S/C30H32N2O4S/c1-35-30-19-17-26(37(33,34)36-25-13-7-3-8-14-25)21-27(30)28-18-16-24(31-28)22-32-20-10-4-9-15-29(32)23-11-5-2-6-12-23/h2-3,5-8,11-14,16-19,21,29,31H,4,9-10,15,20,22H2,1H3
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InChIKey
RTJYNDZSOVYLSA-UHFFFAOYSA-N
Physicochemical Property
logP
6.5753
Rotatable Bonds
8
Heavy Atom Count
37
Polar Areas
71.63
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 9849443
SID: 14811538
ChEMBL ID
CHEMBL433552
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 10 nM
   TI
   LI
   LO
   TS