General Information of the Compound
Compound ID
CP0405510
Compound Name
1-ethyl-2-[5-(5-ethylsulfonyl-2-methoxyphenyl)-1H-pyrrol-2-yl]azepane
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Structure
Formula
C21H30N2O3S
Molecular Weight
390.549
Canonical SMILES
CCN1CCCCCC1c1ccc([nH]1)-c1cc(ccc1OC)S(=O)(=O)CC
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InChI
InChI=1S/C21H30N2O3S/c1-4-23-14-8-6-7-9-20(23)19-12-11-18(22-19)17-15-16(27(24,25)5-2)10-13-21(17)26-3/h10-13,15,20,22H,4-9,14H2,1-3H3
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InChIKey
QHUAVXDRCSLDHT-UHFFFAOYSA-N
Physicochemical Property
logP
4.4209
Rotatable Bonds
6
Heavy Atom Count
27
Polar Areas
62.4
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 22403039
ChEMBL ID
CHEMBL280177
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 7.943 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.995 nM
   TI
   LI
   LO
   TS