Brief Information of the Compound and Protein
Compound Name
3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
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PubChem ID
CID: 11761412
SID: 16869404
Canonical SMILES
COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(F)cc2)CC1
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Compound Formula C24H30FN3O2
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
Ki = 0.34 nM
   TI
   LI
   LO
   TS
2
Ki = 0.69 nM
   TI
   LI
   LO
   TS
CL000389 CHO-DXB11 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3.9 nM
   TI
   LI
   LO
   TS