General Information of the Compound
Compound ID
CP0391643
Compound Name
7-methoxy-N-[4-[4-(5-methoxy-1,3-benzoxazol-2-yl)piperazin-1-yl]butyl]-1-benzofuran-2-carboxamide
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Structure
Formula
C26H30N4O5
Molecular Weight
478.549
Canonical SMILES
COc1ccc2oc(nc2c1)N1CCN(CCCCNC(=O)c2cc3cccc(OC)c3o2)CC1
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InChI
InChI=1S/C26H30N4O5/c1-32-19-8-9-21-20(17-19)28-26(35-21)30-14-12-29(13-15-30)11-4-3-10-27-25(31)23-16-18-6-5-7-22(33-2)24(18)34-23/h5-9,16-17H,3-4,10-15H2,1-2H3,(H,27,31)
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InChIKey
NFJLPYMTHHPACY-UHFFFAOYSA-N
Physicochemical Property
logP
3.9234
Rotatable Bonds
9
Heavy Atom Count
35
Polar Areas
93.21
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11671211
SID: 16810325
ChEMBL ID
CHEMBL202762
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki > 750 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 8500 nM
   TI
   LI
   LO
   TS