General Information of the Compound
Compound ID
CP0496913
Compound Name
4-Bromo-1-ethoxy-naphthalene-2-carboxylic acid [2-(4-phenyl-piperazin-1-yl)-ethyl]-amide
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Structure
Formula
C25H28BrN3O2
Molecular Weight
482.422
Canonical SMILES
CCOc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1ccccc1
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InChI
InChI=1S/C25H28BrN3O2/c1-2-31-24-21-11-7-6-10-20(21)23(26)18-22(24)25(30)27-12-13-28-14-16-29(17-15-28)19-8-4-3-5-9-19/h3-11,18H,2,12-17H2,1H3,(H,27,30)
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InChIKey
NIWKHEZQCOEGDD-UHFFFAOYSA-N
Physicochemical Property
logP
4.553
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
44.81
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44277588
ChEMBL ID
CHEMBL29649
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 251.19 nM
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   LI
   LO
   TS