General Information of the Compound
Compound ID
CP0381460
Compound Name
N-[4-[4-(1H-benzimidazol-2-yl)piperazin-1-yl]butyl]-7-methoxy-1-benzofuran-2-carboxamide
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Structure
Formula
C25H29N5O3
Molecular Weight
447.539
Canonical SMILES
COc1cccc2cc(oc12)C(=O)NCCCCN1CCN(CC1)c1nc2ccccc2[nH]1
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InChI
InChI=1S/C25H29N5O3/c1-32-21-10-6-7-18-17-22(33-23(18)21)24(31)26-11-4-5-12-29-13-15-30(16-14-29)25-27-19-8-2-3-9-20(19)28-25/h2-3,6-10,17H,4-5,11-16H2,1H3,(H,26,31)(H,27,28)
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InChIKey
BGNLEFFBMRBOQF-UHFFFAOYSA-N
Physicochemical Property
logP
3.6499
Rotatable Bonds
8
Heavy Atom Count
33
Polar Areas
86.63
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11568543
SID: 16670819
ChEMBL ID
CHEMBL200243
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Ki > 750 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 8500 nM
   TI
   LI
   LO
   TS