General Information of the Compound
Compound ID
CP0500190
Compound Name
4-[4-methoxy-3-[5-[(2-phenylazepan-1-yl)methyl]-1H-pyrrol-2-yl]phenyl]sulfonylmorpholine
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Structure
Formula
C28H35N3O4S
Molecular Weight
509.672
Canonical SMILES
COc1ccc(cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1)S(=O)(=O)N1CCOCC1
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InChI
InChI=1S/C28H35N3O4S/c1-34-28-14-12-24(36(32,33)31-16-18-35-19-17-31)20-25(28)26-13-11-23(29-26)21-30-15-7-3-6-10-27(30)22-8-4-2-5-9-22/h2,4-5,8-9,11-14,20,27,29H,3,6-7,10,15-19,21H2,1H3
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InChIKey
KYKGECIXEATTSM-UHFFFAOYSA-N
Physicochemical Property
logP
4.8285
Rotatable Bonds
7
Heavy Atom Count
36
Polar Areas
74.87
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 23202799
ChEMBL ID
CHEMBL423198
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01005, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 100 nM
   TI
   LI
   LO
   TS
Protein ID: PT00943, D(3) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 1.585 nM
   TI
   LI
   LO
   TS