| Compound ID |
Compound Name |
Compound Formula |
|
CP0392970
|
(6R,7S,7aR)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-7-(4-fluorophenyl)-1,2,5,6,7,7a-hexahydropyrrolo[1,2-c]imidazol-3-one
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|
C22H19F7N2O2
|
2
|
| 1 |
Activity = 2 nM
|
|
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| 2 |
IC50 = 0.06 nM
|
|
|
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CP0302375
|
(6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C23H20F7NO2
|
3
|
| 1 |
Activity = 2.2 nM
|
|
|
| 2 |
IC50 = 0.06 nM
|
|
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| 3 |
IC50 = 2.2 nM
|
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CP0441002
|
(6R,7S,7aR)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-7-(4-fluorophenyl)-2-methyl-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]imidazol-3-one
Show/Hide
|
C23H21F7N2O2
|
2
|
| 1 |
Activity = 32 nM
|
|
|
| 2 |
IC50 = 0.88 nM
|
|
|
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CP0378384
|
(6R,7S,7aS)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-7-(4-fluorophenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
|
C22H18F7NO3
|
2
|
| 1 |
Activity = 37 nM
|
|
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| 2 |
IC50 = 0.14 nM
|
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|
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CP0516035
|
(6R,7S,7aS)-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-7-phenyl-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
|
C22H19F6NO3
|
2
|
| 1 |
Activity = 37 nM
|
|
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| 2 |
IC50 = 0.27 nM
|
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|
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CP0536133
|
(6S,7R,7aS)-7-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
|
C22H18F7NO3
|
2
|
| 1 |
Activity = 57 nM
|
|
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| 2 |
IC50 = 0.33 nM
|
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|
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CP0233356
|
(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxyphenyl)-11-methyl-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
|
C59H70F6N10O9S
|
1
|
| 1 |
IC50 = 0.01259 nM
|
|
|
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CP0390803
|
(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C24H20F7NO2
|
2
|
| 1 |
IC50 = 0.013 nM
|
|
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| 2 |
IC50 = 0.53 nM
|
|
|
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CP0436682
|
(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-2-(2-(methylthio)ethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
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|
C61H74F6N10O9S
|
1
|
| 1 |
IC50 = 0.0182 nM
|
|
|
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CP0467767
|
1-(4-((3S,4R)-3-(5-(2-(3,5-bis(trifluoromethyl)phenyl)propan-2-yl)-1,2,4-oxadiazol-3-yl)-4-(4-fluoro-2-methylphenyl)pyrrolidine-1-carbonyl)piperidin-1-yl)ethanone
Show/Hide
|
C32H33F7N4O3
|
2
|
| 1 |
IC50 = 0.03 nM
|
|
|
| 2 |
IC50 = 0.17 nM
|
|
|
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CP0447649
|
(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(1-tert-butylpiperidin-4-yl)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C33H37F7N2O2
|
2
|
| 1 |
IC50 = 0.041 nM
|
|
|
| 2 |
IC50 = 0.21 nM
|
|
|
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CP0207087
|
5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
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|
C23H22F6N4O2
|
1
|
| 1 |
IC50 = 0.05 nM
|
|
|
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CP0145456
|
(3R,4S)-N-(2-(3,5-bis(trifluoromethyl)phenyl)propan-2-yl)-1-(1-acetylpiperidine-4-carbonyl)-4-(4-fluoro-2-methylphenyl)-N-methylpyrrolidine-3-carboxamide
Show/Hide
|
C32H36F7N3O3
|
2
|
| 1 |
IC50 = 0.05 nM
|
|
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| 2 |
IC50 = 0.51 nM
|
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|
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CP0145457
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-acetylpiperidine-4-carbonyl)-4-(4-fluoro-2-methylphenyl)-N-methylpyrrolidine-3-carboxamide
Show/Hide
|
C30H32F7N3O3
|
2
|
| 1 |
IC50 = 0.05 nM
|
|
|
| 2 |
IC50 = 0.21 nM
|
|
|
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CP0035758
|
3-[(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-1H-isoindol-2-yl]cyclopent-2-en-1-one
Show/Hide
|
C29H28F7NO2
|
2
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 9.5 nM
|
|
|
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CP0268313
|
(2S,3S)-N-[[2-methoxy-5-(tetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
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|
C20H24N6O
|
2
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
Ki = 0.05012 nM
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|
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CP0412913
|
(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-N-isopropylpyrrolidine-1-carboxamide
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|
C24H25F7N2O2
|
1
|
| 1 |
IC50 = 0.06 nM
|
|
|
|
CP0373676
|
(6R,7S,7aS)-2-((1H-pyrazol-5-yl)methylamino)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C27H25F7N4O2
|
2
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0142501
|
(1S,2R,5aS,7S,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-hydroxyoctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C26H24F7NO3
|
2
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 0.77 nM
|
|
|
|
CP0298044
|
(6R,7S,7aS)-2-amino-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C23H21F7N2O2
|
2
|
| 1 |
IC50 = 0.06 nM
|
|
|
| 2 |
IC50 = 0.38 nM
|
|
|
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CP0145241
|
(1S,2R,5aS,7S,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-hydroxy-7-methyloctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C27H26F7NO3
|
5
|
| 1 |
IC50 = 0.061 nM
|
|
|
| 2 |
IC50 = 0.4 nM
|
|
|
| 3 |
IC50 = 0.7 nM
|
|
|
| 4 |
IC50 = 1.5 nM
|
|
|
| 5 |
IC50 = 1.9 nM
|
|
|
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CP0430409
|
(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(5-oxotetrahydrofuran-3-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C28H24F7NO4
|
2
|
| 1 |
IC50 = 0.066 nM
|
|
|
| 2 |
IC50 = 1.4 nM
|
|
|
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CP0504458
|
(1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-hydroxy-7-methyloctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C27H26F7NO3
|
2
|
| 1 |
IC50 = 0.066 nM
|
|
|
| 2 |
IC50 = 1.2 nM
|
|
|
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CP0304596
|
5-(((2S,3S)-2-(3,5-bis(trifluoromethyl)benzyloxy)-3-(4-fluorophenyl)morpholino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C22H19F7N4O3
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
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CP0444919
|
1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)ethanone
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|
C22H20F7NO2
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
|
CP0505013
|
3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-phenylpyrrolidin-1-yl)cyclopent-2-enone
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|
C25H23F6NO2
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
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CP0526514
|
1-(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carbonyl)piperidin-1-yl)ethanone
Show/Hide
|
C28H29F7N2O3
|
1
|
| 1 |
IC50 = 0.07 nM
|
|
|
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CP0222716
|
1-(4-((3R,4S)-3-(5-(2-(3,5-bis(trifluoromethyl)phenyl)propan-2-yl)-1,2,4-oxadiazol-3-yl)-4-(4-fluoro-2-methylphenyl)pyrrolidine-1-carbonyl)piperidin-1-yl)ethanone
Show/Hide
|
C32H33F7N4O3
|
2
|
| 1 |
IC50 = 0.07 nM
|
|
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| 2 |
IC50 = 6 nM
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|
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CP0296935
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1-(4-((3R,4S)-3-(3-(2-(3,5-bis(trifluoromethyl)phenyl)propan-2-yl)-1,2,4-oxadiazol-5-yl)-4-(4-fluoro-2-methylphenyl)pyrrolidine-1-carbonyl)piperidin-1-yl)ethanone
Show/Hide
|
C32H33F7N4O3
|
2
|
| 1 |
IC50 = 0.07 nM
|
|
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| 2 |
IC50 = 2.8 nM
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CP0447438
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(6R,7S,7aR)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)-1-(4H-1,2,4-triazol-4-yl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C25H21F7N4O2
|
2
|
| 1 |
IC50 = 0.07 nM
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| 2 |
IC50 = 0.83 nM
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CP0377920
|
GR-205171
Show/Hide
|
C21H23F3N6O
|
2
|
| 1 |
IC50 = 0.08 nM
|
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| 2 |
Ki = 0.05012 nM
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CP0412105
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(10S)-3-[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]-10-phenyl-1-oxa-9-azaspiro[4.5]dec-3-ene
Show/Hide
|
C23H22F3N5O2
|
1
|
| 1 |
IC50 = 0.08 nM
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CP0415422
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(6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)-1-methyltetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C24H23F7N2O2
|
2
|
| 1 |
IC50 = 0.08 nM
|
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| 2 |
IC50 = 0.42 nM
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CP0453798
|
(1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-hydroxyoctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C26H24F7NO3
|
2
|
| 1 |
IC50 = 0.08 nM
|
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| 2 |
IC50 = 1.7 nM
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CP0045747
|
((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-benzyl-amine
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|
C27H30N2
|
1
|
| 1 |
IC50 = 0.085 nM
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CP0317460
|
5-(((2S,3S)-2-(3,5-bis(trifluoromethyl)benzyloxy)-3-phenylmorpholino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C22H20F6N4O3
|
1
|
| 1 |
IC50 = 0.09 nM
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CP0107813
|
3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-1,4-oxazinan-4-ylmethyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
Show/Hide
|
C23H21F7N4O3
|
2
|
| 1 |
IC50 = 0.09 nM
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| 2 |
IC50 = 0.1 nM
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CP0479888
|
5-{(2R,3S)-2-[(S)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-3-phenyl-morpholin-4-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C23H22F6N4O3
|
1
|
| 1 |
IC50 = 0.09 nM
|
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CP0434835
|
(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)-N-methyloctahydro-2H-isoindole-2-carboxamide
Show/Hide
|
C26H27F7N2O2
|
2
|
| 1 |
IC50 = 0.09 nM
|
|
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| 2 |
IC50 = 9.8 nM
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CP0444918
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1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)propan-1-one
Show/Hide
|
C23H22F7NO2
|
1
|
| 1 |
IC50 = 0.09 nM
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|
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CP0541080
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1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-phenylpyrrolidin-1-yl)ethanone
Show/Hide
|
C22H21F6NO2
|
1
|
| 1 |
IC50 = 0.09 nM
|
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CP0147400
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(5S,6S,7S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-7-methylazepan-2-one
Show/Hide
|
C23H22F7NO2
|
1
|
| 1 |
IC50 = 0.09 nM
|
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CP0464720
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N-[[2-[[2-cyclopropyloxy-5-(trifluoromethoxy)phenyl]methylamino]-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-6-yl]methyl]methanesulfonamide
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|
C26H31F4N3O4S
|
1
|
| 1 |
IC50 = 0.09 nM
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CP0215155
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-4-(4-fluoro-2-methylphenyl)-N-methyl-1-(2-methylpyrazine-5-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C28H25F7N4O2
|
2
|
| 1 |
IC50 = 0.09 nM
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| 2 |
IC50 = 8 nM
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CP0470232
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(tetrahydro-2H-pyran-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C29H28F7NO3
|
2
|
| 1 |
IC50 = 0.09 nM
|
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| 2 |
IC50 = 3.2 nM
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CP0099706
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(6R,7S,7aR)-1-amino-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
|
C23H21F7N2O2
|
2
|
| 1 |
IC50 = 0.09 nM
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| 2 |
IC50 = 0.6 nM
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CP0142500
|
(1S,2R,5aS,7S,8aR,8bS)-7-amino-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C26H25F7N2O2
|
2
|
| 1 |
IC50 = 0.09 nM
|
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| 2 |
IC50 = 1 nM
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CP0529115
|
5-{(2R,3S)-2-[(R)-1-(3-Fluoro-5-trifluoromethyl-phenyl)-ethoxy]-3-phenyl-morpholin-4-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C22H22F4N4O3
|
1
|
| 1 |
IC50 = 0.1 nM
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CP0465260
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5-{(5S,10S)-5-(4-Fluoro-phenyl)-10-[2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-1,8-dioxa-4-aza-spiro[5.5]undec-4-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C26H26F4N8O4
|
1
|
| 1 |
IC50 = 0.1 nM
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CP0479745
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(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-[2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
|
C23H23F4N5O3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
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CP0461323
|
5-{3-[2-Methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-6-phenyl-1-oxa-7-aza-spiro[4.5]dec-7-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C26H27F3N8O3
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
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CP0493097
|
3-[(4R,5S)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-2H-isoindol-2-yl]-2-methylcyclopent-2-en-1-one
Show/Hide
|
C30H30F7NO2
|
2
|
| 1 |
IC50 = 0.1 nM
|
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| 2 |
IC50 = 11 nM
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CP0524234
|
(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-N-ethyl-4-(4-fluorophenyl)pyrrolidine-1-carboxamide
Show/Hide
|
C23H23F7N2O2
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
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CP0497488
|
N-[[2-cyclopropyloxy-5-(trifluoromethoxy)phenyl]methyl]-1-phenyl-8-azabicyclo[3.2.1]octan-2-amine
Show/Hide
|
C24H27F3N2O2
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
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CP0459004
|
4-((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-5-oxo-1,2,3,5,8,8a-hexahydroindolizin-7-yl)pyridine 1-oxide
Show/Hide
|
C29H23F7N2O3
|
2
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| 1 |
IC50 = 0.1 nM
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| 2 |
IC50 = 2.1 nM
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CP0529826
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3-[2-(4-Chloro-phenyl)-1,5-dimethyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C30H32ClN3O2
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1
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| 1 |
IC50 = 0.11 nM
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CP0461104
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7-(1H-Imidazol-4-ylmethyl)-3-[2-methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-6-phenyl-1-oxa-7-aza-spiro[4.5]decane
Show/Hide
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C27H28F3N7O2
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1
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| 1 |
IC50 = 0.11 nM
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CP0504777
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3-[2-Methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-6-phenyl-1-oxa-7-aza-spiro[4.5]decane
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C23H24F3N5O2
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1
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| 1 |
IC50 = 0.11 nM
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CP0493098
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(4R,5S)-2-Acetyl-5-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-1H-isoindole
Show/Hide
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C26H26F7NO2
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 7.8 nM
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CP0321388
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3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)cyclopent-2-enone
Show/Hide
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C25H22F7NO2
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1
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| 1 |
IC50 = 0.11 nM
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CP0412910
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3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)-4-methylcyclopent-2-enone
Show/Hide
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C26H24F7NO2
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1
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| 1 |
IC50 = 0.11 nM
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CP0444917
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(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-N-methylpyrrolidine-1-carboxamide
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C22H21F7N2O2
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1
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| 1 |
IC50 = 0.11 nM
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CP0467292
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(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-phenyl-8-aza-bicyclo[3.2.1]octan-6-yl)methanol
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C25H29F3N2O3
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1
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| 1 |
IC50 = 0.11 nM
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CP0473499
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(oxazol-2-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C27H21F7N2O3
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 6.4 nM
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CP0485670
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(2-fluoropyridin-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H22F8N2O2
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 11.7 nM
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CP0494218
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(3,5-dimethylisoxazol-4-yl)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H25F7N2O3
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 5.6 nM
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CP0869907
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(5-oxotetrahydrofuran-3-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one hydrochloride
Show/Hide
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C28H25ClF7NO4
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 2.4 nM
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CP0235005
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(1S,2R,5aS,7R,8aR,8bS)-7-amino-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C26H25F7N2O2
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2
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| 1 |
IC50 = 0.11 nM
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| 2 |
IC50 = 1 nM
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CP0387532
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(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-3-((2R,3R,4S,5S,6R)-6-ethyl-3,4,5-trihydroxytetrahydro-2H-pyran-2-yloxy)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
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C70H89F6N11O15
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2
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| 1 |
IC50 = 0.1175 nM
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| 2 |
Ki = 0.052 nM
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CP0522220
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-1-methyl-2-(6-methyl-pyridin-3-yl)-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H32ClN3O2
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1
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| 1 |
IC50 = 0.12 nM
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CP0540270
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-1-methyl-2-(5-trifluoromethyl-pyridin-2-yl)-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H29ClF3N3O2
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1
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| 1 |
IC50 = 0.12 nM
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CP0412908
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4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)-1-methyl-1H-pyrrol-2(5H)-one
Show/Hide
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C25H23F7N2O2
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1
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| 1 |
IC50 = 0.12 nM
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CP0524237
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((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)(5-methylpyrazin-2-yl)methanone
Show/Hide
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C26H22F7N3O2
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1
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| 1 |
IC50 = 0.12 nM
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CP0528083
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(S)-5-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carbonyl)-1-methylpyrrolidin-2-one
Show/Hide
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C26H25F7N2O3
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1
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| 1 |
IC50 = 0.12 nM
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CP0541704
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(5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-1-methylazepan-2-one
Show/Hide
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C23H22F7NO2
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1
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| 1 |
IC50 = 0.12 nM
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CP0383598
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Bifunctional Peptide Ligand, 5 (TY005)
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C59H69F6N9O10S
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5
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| 1 |
IC50 = 0.1259 nM
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| 2 |
IC50 = 0.955 nM
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| 3 |
Ki = 0.082 nM
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| 4 |
Ki = 0.084 nM
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| 5 |
Ki = 0.29 nM
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CP0437585
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(2S,3S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-3-phenyl-4-(2H-[1,2,4]triazol-1-ylmethyl)-morpholine
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C22H20F6N4O2
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1
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| 1 |
IC50 = 0.13 nM
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CP0454628
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2-(4-{3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propionyl}-piperazin-1-yl)-N-methyl-N-phenyl-acetamide
Show/Hide
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C31H32Cl2N4O2
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1
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| 1 |
IC50 = 0.13 nM
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CP0372279
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3-[(4R,5S)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-2H-isoindol-2-yl]cyclohex-2-en-1-one
Show/Hide
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C30H30F7NO2
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2
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| 1 |
IC50 = 0.13 nM
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| 2 |
IC50 = 22 nM
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CP0471352
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3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)-2-methylcyclopent-2-enone
Show/Hide
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C26H24F7NO2
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1
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| 1 |
IC50 = 0.13 nM
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CP0541078
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3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-phenylpyrrolidin-1-yl)-5,5-dimethylcyclohex-2-enone
Show/Hide
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C28H29F6NO2
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1
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| 1 |
IC50 = 0.13 nM
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CP0442587
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N-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]-1-phenyl-8-azabicyclo[3.2.1]octan-2-amine
Show/Hide
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C22H25F3N2O2
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1
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| 1 |
IC50 = 0.13 nM
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CP0429903
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(6R,7S,7aR)-1-((1H-pyrazol-5-yl)methylamino)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
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C27H25F7N4O2
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2
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| 1 |
IC50 = 0.13 nM
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| 2 |
IC50 = 1.83 nM
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CP0440143
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(6R,7S,7aS)-6-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-((5-((dimethylamino)methyl)-1H-1,2,3-triazol-4-yl)methylamino)-7-(4-fluorophenyl)tetrahydro-1H-pyrrolizin-3(2H)-one
Show/Hide
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C29H31F7N6O2
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2
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| 1 |
IC50 = 0.13 nM
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| 2 |
IC50 = 1.4 nM
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CP0390800
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(1-methyl-1H-pyrazol-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C28H24F7N3O2
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2
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| 1 |
IC50 = 0.13 nM
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| 2 |
IC50 = 5.4 nM
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CP0040635
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(2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-phenyl-piperidin-3-yl)-amine
Show/Hide
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C20H23F3N2O2
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1
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| 1 |
IC50 = 0.14 nM
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CP0402729
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3-[2-(4-Bromo-phenyl)-1,5-dimethyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C30H32BrN3O2
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1
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| 1 |
IC50 = 0.14 nM
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CP0454639
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3-[1,5-Dimethyl-2-(4-trifluoromethyl-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C31H32F3N3O2
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1
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| 1 |
IC50 = 0.14 nM
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CP0510766
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(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-N-tert-butyl-4-(4-fluorophenyl)pyrrolidine-1-carboxamide
Show/Hide
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C25H27F7N2O2
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1
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| 1 |
IC50 = 0.14 nM
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CP0442316
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(5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)azepan-2-one
Show/Hide
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C22H20F7NO2
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1
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| 1 |
IC50 = 0.14 nM
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CP0529997
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(S)-5-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)methyl)-1-methylpyrrolidin-2-one
Show/Hide
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C28H31F7N2O2
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1
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| 1 |
IC50 = 0.14 nM
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CP0402037
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(pyridin-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H23F7N2O2
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2
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| 1 |
IC50 = 0.14 nM
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| 2 |
IC50 = 8.1 nM
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CP0036567
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(1S,2R,5aS,7R,8aR,8bS)-7-(benzylamino)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C33H31F7N2O2
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2
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| 1 |
IC50 = 0.14 nM
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| 2 |
IC50 = 1.3 nM
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CP0372659
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(1S,2R,5aR,7S,8aS,8bS)-7-(benzylamino)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C33H31F7N2O2
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2
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| 1 |
IC50 = 0.14 nM
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| 2 |
IC50 = 2.3 nM
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CP0495439
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl]-propan-1-one
Show/Hide
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C29H29Cl2N3O2
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1
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| 1 |
IC50 = 0.15 nM
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CP0389529
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(3aR,4R,5S,7aS)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)octahydro-1H-isoindole
Show/Hide
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C24H24F7NO
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2
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| 1 |
IC50 = 0.15 nM
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| 2 |
IC50 = 7.3 nM
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CP0378416
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1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)-2-methylpropan-1-one
Show/Hide
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C24H24F7NO2
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1
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| 1 |
IC50 = 0.15 nM
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CP0422171
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3-((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-5-oxo-1,2,3,5,8,8a-hexahydroindolizin-7-yl)pyridine 1-oxide
Show/Hide
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C29H23F7N2O3
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2
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| 1 |
IC50 = 0.15 nM
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| 2 |
IC50 = 2.3 nM
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CP0485673
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(3-methyl-1,2,4-oxadiazol-5-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C27H22F7N3O3
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2
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| 1 |
IC50 = 0.15 nM
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| 2 |
IC50 = 5.1 nM
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CP0499817
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(1H-pyrazol-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C27H22F7N3O2
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2
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| 1 |
IC50 = 0.15 nM
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| 2 |
IC50 = 7.7 nM
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CP0467857
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N-[1-[3-[5-chloro-2-(4-chlorophenyl)-1-methylindol-3-yl]propanoyl]piperidin-4-yl]-N-phenylpropanamide
Show/Hide
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C32H33Cl2N3O2
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1
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| 1 |
IC50 = 0.16 nM
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CP0470514
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H30Cl2N2O2
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2
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| 1 |
IC50 = 0.16 nM
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| 2 |
IC50 = 0.21 nM
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CP0524233
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4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)furan-2(5H)-one
Show/Hide
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C24H20F7NO3
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1
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| 1 |
IC50 = 0.16 nM
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CP0524235
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((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-phenylpyrrolidin-1-yl)(morpholino)methanone
Show/Hide
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C25H26F6N2O3
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1
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| 1 |
IC50 = 0.16 nM
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CP0376638
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-N-((4H-1,2,4-triazol-3-yl)methyl)-2-(4-fluorophenyl)-N-methylcyclopentanamine
Show/Hide
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C25H25F7N4O
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1
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| 1 |
IC50 = 0.16 nM
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CP0516258
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-N-((4H-1,2,4-triazol-3-yl)methyl)-N-ethyl-2-(4-fluorophenyl)cyclopentanamine
Show/Hide
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C26H27F7N4O
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1
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| 1 |
IC50 = 0.16 nM
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CP0390804
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(4-hydroxypiperidin-1-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H29F7N2O3
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2
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| 1 |
IC50 = 0.16 nM
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| 2 |
IC50 = 11 nM
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CP0494217
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(pyrimidin-5-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C28H22F7N3O2
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2
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| 1 |
IC50 = 0.16 nM
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| 2 |
IC50 = 4 nM
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CP0194560
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(1S,2R,5aS,7S,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-ethyl-1-(4-fluorophenyl)-7-hydroxyoctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C28H28F7NO3
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2
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| 1 |
IC50 = 0.16 nM
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| 2 |
IC50 = 1.7 nM
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CP0456322
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(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
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C62H76F6N10O9
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2
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| 1 |
IC50 = 0.166 nM
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| 2 |
Ki = 0.075 nM
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CP0319172
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-4-morpholin-4-ylbutanamide
Show/Hide
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C29H31F6N3O3
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3
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| 1 |
IC50 = 0.17 nM
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| 2 |
IC50 = 0.24 nM
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| 3 |
IC50 = 1.4 nM
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CP0394374
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(2-methoxyethyl)amino)acetamide
Show/Hide
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C26H29F7N2O3
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1
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| 1 |
IC50 = 0.17 nM
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CP0215156
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1-(4-((3S,4R)-3-(3-(2-(3,5-bis(trifluoromethyl)phenyl)propan-2-yl)-1,2,4-oxadiazol-5-yl)-4-(4-fluoro-2-methylphenyl)pyrrolidine-1-carbonyl)piperidin-1-yl)ethanone
Show/Hide
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C32H33F7N4O3
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2
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| 1 |
IC50 = 0.17 nM
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| 2 |
IC50 = 20 nM
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CP0099707
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(1S,2R,5aS,7S,8aR,8bS)-7-(benzylamino)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
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C33H31F7N2O2
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2
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| 1 |
IC50 = 0.17 nM
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| 2 |
IC50 = 1.8 nM
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CP0375711
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(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxyphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-1-oxo-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propan-2-yl)pyrrolidine-2-carboxamide
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C63H76F6N10O15
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2
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| 1 |
IC50 = 0.1778 nM
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| 2 |
Ki = 0.077 nM
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CP0524265
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1-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-phenylpyrrolidin-1-yl)-2,2-dimethylpropan-1-one
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C25H27F6NO2
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1
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| 1 |
IC50 = 0.18 nM
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CP0528080
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3-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(phenyl)pyrrolidin-1-yl)-6,6-dimethylcyclohex-2-enone
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C28H29F6NO2
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1
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| 1 |
IC50 = 0.18 nM
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CP0181626
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(1-tert-butyl-1,2,3,6-tetrahydropyridin-4-yl)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
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C33H35F7N2O2
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2
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| 1 |
IC50 = 0.18 nM
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| 2 |
IC50 = 1.9 nM
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CP0458997
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(4-hydroxycyclohex-1-enyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C30H28F7NO3
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2
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| 1 |
IC50 = 0.18 nM
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| 2 |
IC50 = 13 nM
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CP0462871
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(3,6-dihydro-2H-pyran-4-yl)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H26F7NO3
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2
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| 1 |
IC50 = 0.18 nM
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| 2 |
IC50 = 9.6 nM
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CP0510237
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(pyridin-3-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H23F7N2O2
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2
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| 1 |
IC50 = 0.18 nM
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| 2 |
IC50 = 8.5 nM
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CP0373267
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(3S,6S,12S,17R,20S)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-3-butyl-2,5,8,11,19-pentaoxo-14,15-dithia-1,4,7,10,18-pentazabicyclo[18.3.0]tricosane-17-carboxamide
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C57H64F6N10O9S2
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2
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| 1 |
IC50 = 0.1862 nM
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| 2 |
Ki = 0.1 nM
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CP0524638
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3-[5-Acetyl-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-benzyl-4-hydroxy-piperidin-1-yl)-propan-1-one
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C32H33ClN2O3
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1
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| 1 |
IC50 = 0.19 nM
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CP0378747
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(6S,7S)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-6,7,8,9-tetrahydro-2H-[1,2,4]triazolo[4,3-a]azepin-3(5H)-one
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C23H20F7N3O2
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1
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| 1 |
IC50 = 0.19 nM
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CP0394151
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)acetamide
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C24H25F7N2O2
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1
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| 1 |
IC50 = 0.19 nM
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CP0467298
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-N-methylacetamide
Show/Hide
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C25H27F7N2O2
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1
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| 1 |
IC50 = 0.19 nM
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CP0133180
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((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-(2-methoxy-benzyl)-amine
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C28H32N2O
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5
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| 1 |
IC50 = 0.2 nM
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| 2 |
IC50 = 0.4 nM
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| 3 |
IC50 = 0.45 nM
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| 4 |
IC50 = 0.5 nM
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| 5 |
IC50 = 22 nM
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CP0042808
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(2S,3S)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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C29H27F6NO
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3
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| 1 |
IC50 = 0.2 nM
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| 2 |
IC50 = 1.3 nM
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| 3 |
IC50 = 2 nM
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CP0050947
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(2R,3S)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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C29H27F6NO
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1
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| 1 |
IC50 = 0.2 nM
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CP0534355
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3-[2-(4-Isopropyl-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C32H37N3O2
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1
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| 1 |
IC50 = 0.2 nM
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CP0541772
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(S)-5-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)methyl)pyrrolidin-2-one
Show/Hide
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C27H29F7N2O2
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1
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| 1 |
IC50 = 0.2 nM
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CP0493051
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5-(4-Fluoro-phenyl)-7-methyl-8-oxo-7,8-dihydro-[1,7]naphthyridine-6-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
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C26H18F7N3O2
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1
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| 1 |
IC50 = 0.21 nM
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CP0427605
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(1S,2R,5aS,7R,8aR,8bS)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-ethyl-1-(4-fluorophenyl)-7-hydroxyoctahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C28H28F7NO3
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2
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| 1 |
IC50 = 0.21 nM
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| 2 |
IC50 = 2.3 nM
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CP0243357
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(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-1-(4H-[1,2,4]triazol-3-ylmethyl)-piperidine
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C23H22F6N4O
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1
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| 1 |
IC50 = 0.22 nM
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CP0383925
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-bromo-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H30BrClN2O2
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1
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| 1 |
IC50 = 0.22 nM
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CP0497684
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-pyrrolo[2,3-c]pyridin-3-yl]-propan-1-one
Show/Hide
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C29H29Cl2N3O2
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1
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| 1 |
IC50 = 0.22 nM
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CP0403801
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(1-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
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C31H36F6N2O2
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1
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| 1 |
IC50 = 0.22 nM
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CP0371844
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(7S,8R)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-8-(4-fluorophenyl)-6,7,8,9-tetrahydro-2H-[1,2,4]triazolo[4,3-a]azepin-3(5H)-one
Show/Hide
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C23H20F7N3O2
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1
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| 1 |
IC50 = 0.22 nM
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CP0526253
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(3R,5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-3-methylazepan-2-one
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C23H22F7NO2
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1
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| 1 |
IC50 = 0.23 nM
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CP0432090
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5-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
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C25H25F7N4O2
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1
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| 1 |
IC50 = 0.23 nM
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CP0507702
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-pyrrolidin-1-yl-ethanone
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C27H30F6N2O2
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1
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| 1 |
IC50 = 0.24 nM
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CP0454127
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(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carbaldehyde
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C21H18F7NO2
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1
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| 1 |
IC50 = 0.24 nM
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CP0529996
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(ethyl)amino)acetamide
Show/Hide
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C25H27F7N2O2
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1
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| 1 |
IC50 = 0.24 nM
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CP0497487
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N-[[2-[[2-cyclopropyloxy-5-(trifluoromethoxy)phenyl]methylamino]-1-(4-fluorophenyl)-8-azabicyclo[3.2.1]octan-6-yl]methyl]benzenesulfonamide
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C31H33F4N3O4S
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1
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| 1 |
IC50 = 0.24 nM
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CP0432089
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-N-(2-methoxyethyl)cyclopentanamine
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C24H26F7NO2
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1
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| 1 |
IC50 = 0.25 nM
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CP0453095
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-N-ethyl-2-(4-fluorophenyl)cyclopentanamine
Show/Hide
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C23H24F7NO
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1
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| 1 |
IC50 = 0.25 nM
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CP0485211
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(R)-5-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)methyl)pyrrolidin-2-one
Show/Hide
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C27H29F7N2O2
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1
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| 1 |
IC50 = 0.25 nM
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CP0496723
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-N-methylcyclopentanamine
Show/Hide
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C22H22F7NO
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1
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| 1 |
IC50 = 0.25 nM
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CP0474555
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(4R,5S)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)-2-methyloctahydro-1H-isoindole
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C25H26F7NO
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2
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| 1 |
IC50 = 0.255 nM
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| 2 |
IC50 = 17 nM
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CP0514933
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(1,1-dimethyl-2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C34H42F6N2O2
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1
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| 1 |
IC50 = 0.26 nM
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CP0524172
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5-{(2R,3S)-3-Phenyl-2-[(R)-1-(3-trifluoromethyl-phenyl)-ethoxy]-morpholin-4-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
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C22H23F3N4O3
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1
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| 1 |
IC50 = 0.27 nM
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CP0405791
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-vinyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C32H33ClN2O2
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1
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| 1 |
IC50 = 0.27 nM
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CP0376640
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N-[(1R,2S,3S)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)cyclopentyl]-2-(1H-imidazol-5-yl)-N-methylacetamide
Show/Hide
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C27H26F7N3O2
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1
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| 1 |
IC50 = 0.27 nM
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CP0467329
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2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-(4-fluorophenyl)-N-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane-6-carboxamide
Show/Hide
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C31H31F4N3O5S
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1
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| 1 |
IC50 = 0.27 nM
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CP0373892
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(2-oxo-1,2-dihydropyridin-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H23F7N2O3
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2
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| 1 |
IC50 = 0.27 nM
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| 2 |
IC50 = 3.9 nM
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CP0454736
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C29H29Cl2N3O2
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1
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| 1 |
IC50 = 0.28 nM
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CP0560095
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tert-butyl (2R,3S,4R)-4-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Show/Hide
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C26H28F7NO4
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1
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| 1 |
IC50 = 0.28 nM
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CP0436136
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(6S,7S)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine
Show/Hide
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C24H21F7N2O
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1
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| 1 |
IC50 = 0.28 nM
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CP0376670
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-N-(2-hydroxyethyl)-N-methylacetamide
Show/Hide
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C27H31F7N2O3
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1
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| 1 |
IC50 = 0.28 nM
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CP0482783
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-4-pyrrolidin-1-ylbutanamide
Show/Hide
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C29H31F6N3O2
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1
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| 1 |
IC50 = 0.3 nM
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CP0480965
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2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-N,N-dimethyl-acetamide
Show/Hide
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C24H26F6N2O2
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1
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| 1 |
IC50 = 0.3 nM
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CP0492798
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1-(4-Benzyl-piperazin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C29H29Cl2N3O
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1
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| 1 |
IC50 = 0.3 nM
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CP0507558
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C30H34F6N2O3
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1
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| 1 |
IC50 = 0.3 nM
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CP0498223
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(3S,10S)-3-[2-methoxy-5-(trifluoromethoxy)phenyl]-10-phenyl-1-oxa-9-azaspiro[4.5]decane
Show/Hide
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C22H24F3NO3
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1
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| 1 |
IC50 = 0.3 nM
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CP0515112
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1-(4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carbonyl)piperazin-1-yl)ethanone
Show/Hide
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C27H28F7N3O3
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1
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| 1 |
IC50 = 0.3 nM
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CP0376637
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-N-(2-methoxyethyl)acetamide
Show/Hide
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C27H31F7N2O3
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1
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| 1 |
IC50 = 0.3 nM
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CP0401410
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1-((2R,3S,4R)-4-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-2-(hydroxymethyl)pyrrolidin-1-yl)ethanone
Show/Hide
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C23H22F7NO3
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2
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| 1 |
IC50 = 0.3 nM
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| 2 |
IC50 = 43.1 nM
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CP0467818
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2-Benzhydryl-3-(3-iodo-5-methyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C28H30INO
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1
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| 1 |
IC50 = 0.32 nM
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CP0485376
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-imidazol-1-yl-ethanone
Show/Hide
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C26H25F6N3O2
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1
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| 1 |
IC50 = 0.32 nM
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CP0528973
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3-[2-(4-Isopropyl-phenyl)-1,5-dimethyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C33H39N3O2
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1
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| 1 |
IC50 = 0.33 nM
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CP0461193
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N-[4-(4-benzyl-4-hydroxypiperidin-1-yl)-1-phenylcyclohexyl]-2-[3,5-bis(trifluoromethyl)phenyl]propanamide
Show/Hide
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C35H38F6N2O2
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1
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| 1 |
IC50 = 0.33 nM
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CP0495941
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3-(3,5-bis-trifluoromethyl-phenyl)-3-methyl-1-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-pyrrolidin-2-one
Show/Hide
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C33H38F6N2O2
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1
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| 1 |
IC50 = 0.33 nM
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CP0451883
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(5S,6S,7S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-1,7-dimethylazepan-2-one
Show/Hide
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C24H24F7NO2
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1
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| 1 |
IC50 = 0.33 nM
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CP0469891
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-[4-(3-methyl-butyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C27H33Cl2N3O
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1
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| 1 |
IC50 = 0.34 nM
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CP0438525
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4-[4-(4-Fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cyclohexanecarboxylic acid 3,5-bis-trifluoromethyl-benzylamide
Show/Hide
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C33H33F7N2O
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1
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| 1 |
IC50 = 0.34 nM
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CP0468049
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C31H36F6N2O2
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1
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| 1 |
IC50 = 0.34 nM
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CP0435506
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2-(3,5-bis-trifluoromethyl-phenyl)-N-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C31H36F6N2O2
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1
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| 1 |
IC50 = 0.34 nM
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CP0524236
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(S)-4-((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carbonyl)oxazolidin-2-one
Show/Hide
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C24H21F7N2O4
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1
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| 1 |
IC50 = 0.34 nM
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CP0456464
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(S)-5-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentylamino)methyl)pyrrolidin-2-one
Show/Hide
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C26H27F7N2O2
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1
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| 1 |
IC50 = 0.34 nM
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CP0496988
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-cyclohexyl-piperazin-1-yl)-propan-1-one
Show/Hide
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C28H33Cl2N3O
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1
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| 1 |
IC50 = 0.35 nM
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CP0403587
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(2,2-dimethyl-1-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C33H40F6N2O2
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1
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| 1 |
IC50 = 0.35 nM
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CP0497583
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3-(2-Methoxy-5-trifluoromethoxy-phenyl)-6-phenyl-1-oxa-7-aza-spiro[4.5]dec-3-ene
Show/Hide
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C22H22F3NO3
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1
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| 1 |
IC50 = 0.35 nM
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CP0439616
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-3-piperidin-4-ylpropanamide
Show/Hide
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C29H31F6N3O2
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1
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| 1 |
IC50 = 0.37 nM
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CP0407811
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(3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-N,N-dimethylpyrrolidine-1-carboxamide
Show/Hide
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C23H23F7N2O2
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1
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| 1 |
IC50 = 0.38 nM
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CP0458104
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-1-morpholinoethanone
Show/Hide
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C28H31F7N2O3
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1
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| 1 |
IC50 = 0.38 nM
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CP0529886
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1-Benzyl-4-{3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propionyl}-piperazin-2-one
Show/Hide
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C29H27Cl2N3O2
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1
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| 1 |
IC50 = 0.39 nM
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CP0438212
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(4-isopropyl-piperazin-1-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C30H37F6N3O
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1
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| 1 |
IC50 = 0.39 nM
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CP0458105
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-N,N-dimethylacetamide
Show/Hide
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C26H29F7N2O2
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1
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| 1 |
IC50 = 0.39 nM
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CP0402036
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(4-(hydroxymethyl)phenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C31H26F7NO3
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2
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| 1 |
IC50 = 0.39 nM
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| 2 |
IC50 = 23 nM
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CP0208213
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-2-pyridin-4-ylacetamide
Show/Hide
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C28H23F6N3O2
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3
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| 1 |
IC50 = 0.4 nM
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| 2 |
IC50 = 0.5 nM
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| 3 |
IC50 = 10 nM
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CP0425149
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2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-fluoro-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
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C25H24F7N5O
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1
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| 1 |
IC50 = 0.4 nM
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CP0543765
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2-((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentylamino)acetamide
Show/Hide
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C23H23F7N2O2
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1
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| 1 |
IC50 = 0.4 nM
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CP0502376
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-7-(3-ethyl-1,2,4-oxadiazol-5-yl)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C28H24F7N3O3
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2
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| 1 |
IC50 = 0.4 nM
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| 2 |
IC50 = 27 nM
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CP0436139
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(4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-7-methylazepan-2-one
Show/Hide
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C23H22F7NO2
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1
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| 1 |
IC50 = 0.41 nM
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CP0467299
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4-((((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)methyl)-1H-imidazol-2(3H)-one
Show/Hide
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C26H26F7N3O2
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1
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| 1 |
IC50 = 0.41 nM
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CP0524165
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5-({[(S)-2-(3-tert-Butyl-5-methyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C24H32N4O2
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1
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| 1 |
IC50 = 0.42 nM
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CP0460897
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(1-oxo-2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C32H36F6N2O3
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1
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| 1 |
IC50 = 0.42 nM
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CP0303745
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5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C21H20F6N4O2
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1
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| 1 |
IC50 = 0.43 nM
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CP0371847
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(7S,8R)-7-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-8-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-imidazo[1,2-a]azepine
Show/Hide
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C24H21F7N2O
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1
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| 1 |
IC50 = 0.43 nM
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CP0421296
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-1-(pyrrolidin-1-yl)ethanone
Show/Hide
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C28H31F7N2O2
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1
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| 1 |
IC50 = 0.43 nM
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CP0377828
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1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-[5-methyl-2-(4-trifluoromethyl-phenyl)-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H30F3N3O2
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1
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| 1 |
IC50 = 0.44 nM
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CP0442314
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(3R,5S,6S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(4-fluorophenyl)-1,3-dimethylazepan-2-one
Show/Hide
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C24H24F7NO2
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1
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| 1 |
IC50 = 0.44 nM
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CP0422116
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(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
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C63H78F6N10O9
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2
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| 1 |
IC50 = 0.4677 nM
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| 2 |
Ki = 0.21 nM
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CP0496306
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-3-pyridin-4-ylpropanamide
Show/Hide
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C29H25F6N3O2
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1
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| 1 |
IC50 = 0.47 nM
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CP0454129
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((3S,4R)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidin-1-yl)(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone
Show/Hide
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C27H23F10N5O2
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1
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| 1 |
IC50 = 0.47 nM
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CP0435507
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3-(3,5-bis-trifluoromethyl-phenyl)-3-methoxy-1-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-pyrrolidin-2-one
Show/Hide
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C33H38F6N2O3
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1
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| 1 |
IC50 = 0.48 nM
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CP0437114
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4-((1r,4r)-4-(3-(3,5-bis(trifluoromethyl)phenyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-phenylcyclohexyl)-1-(2-chlorophenyl)piperazin-2-one
Show/Hide
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C35H34ClF6N3O2
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1
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| 1 |
IC50 = 0.48 nM
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CP0459713
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4-((1r,4r)-4-(3-(3,5-bis(trifluoromethyl)phenyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-phenylcyclohexyl)-1-phenylpiperazin-2-one
Show/Hide
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C35H35F6N3O2
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1
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| 1 |
IC50 = 0.48 nM
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CP0373845
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(3S,6S,12S,17S,20S)-12-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-6-benzyl-N-[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-3-butyl-2,5,8,11,19-pentaoxo-14,15-dithia-1,4,7,10,18-pentazabicyclo[18.3.0]tricosane-17-carboxamide
Show/Hide
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C57H64F6N10O9S2
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2
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| 1 |
IC50 = 0.4898 nM
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| 2 |
Ki = 0.25 nM
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CP0526252
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(4R,5S,7R)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-1,7-dimethylazepan-2-one
Show/Hide
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C24H24F7NO2
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1
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| 1 |
IC50 = 0.49 nM
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CP0222920
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(+) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
Show/Hide
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C19H24N2O
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3
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| 1 |
IC50 = 0.5 nM
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| 2 |
IC50 = 0.6 nM
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| 3 |
Ki = 0.2512 nM
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CP0454846
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(R)-(2-Methoxy-benzyl)-((S)-2-phenyl-piperidin-3-yl)-amine
Show/Hide
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C19H24N2O
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1
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| 1 |
IC50 = 0.5 nM
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CP0538224
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-dimethylamino-ethanone
Show/Hide
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C25H28F6N2O2
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1
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| 1 |
IC50 = 0.5 nM
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CP0526584
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3-(3,5-bis-trifluoromethyl-phenyl)-1-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-pyrrolidin-2-one
Show/Hide
|
C32H36F6N2O2
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1
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| 1 |
IC50 = 0.5 nM
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CP0432906
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2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C25H25F6N5O
|
1
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| 1 |
IC50 = 0.5 nM
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CP0510236
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(2-methylpyridin-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C30H25F7N2O2
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2
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| 1 |
IC50 = 0.51 nM
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| 2 |
IC50 = 34 nM
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CP0551227
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-N-(2-methoxyethyl)-N-methylcyclopentanamine
Show/Hide
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C25H28F7NO2
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1
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| 1 |
IC50 = 0.52 nM
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CP0400200
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(4R,5S)-5-{(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy}-4-(4-fluorophenyl)-2-pyrazin-2-yloctahydro-1H-isoindole
Show/Hide
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C28H26F7N3O
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2
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| 1 |
IC50 = 0.525 nM
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| 2 |
IC50 = 73 nM
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CP0270441
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(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-(1H-imidazol-2-ylmethyl)-2-phenyl-piperidine
Show/Hide
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C24H23F6N3O
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1
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| 1 |
IC50 = 0.53 nM
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CP0457038
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1-(4-Acetyl-4-phenyl-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C31H30Cl2N2O2
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1
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| 1 |
IC50 = 0.53 nM
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CP0374764
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1-Amino-2-[1-(3,5-bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-ethanol
Show/Hide
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C26H24F6N2O2
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2
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| 1 |
IC50 = 0.53 nM
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| 2 |
IC50 = 0.85 nM
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CP0446040
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(4R,5S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)-1-methylazepan-2-one
Show/Hide
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C23H22F7NO2
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1
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| 1 |
IC50 = 0.53 nM
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CP0307084
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2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-acetamide
Show/Hide
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C26H24F6N2O2
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2
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| 1 |
IC50 = 0.53 nM
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| 2 |
Ki = 0.9 nM
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CP0532406
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1-(4-Benzyl-4-fluoro-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H29Cl2FN2O
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1
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| 1 |
IC50 = 0.55 nM
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CP0421297
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(1R,2S,3S)-N-((1H-imidazol-2-yl)methyl)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentanamine
Show/Hide
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C25H24F7N3O
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1
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| 1 |
IC50 = 0.55 nM
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CP0520149
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5-[(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undec-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C24H27FN4O4
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1
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| 1 |
IC50 = 0.56 nM
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CP0478200
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3,5-di(trifluoromethyl)benzyl 3-(1H-3-indolyl)-2-[1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-ylcarboxamido]-(2S)-propanoate
Show/Hide
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C34H32F6N4O3S
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1
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| 1 |
IC50 = 0.58 nM
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CP0560090
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(3S,4R)-N-((2H-1,2,3-triazol-4-yl)methyl)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)pyrrolidine-1-carboxamide
Show/Hide
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C24H22F7N5O2
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1
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| 1 |
IC50 = 0.58 nM
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CP0526475
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-1-(2-methylpyrazine-5-carbonyl)-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C27H24F6N4O2
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1
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| 1 |
IC50 = 0.58 nM
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CP0363629
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5-Dimethylamino-pentanoic acid [(S)-4-(3,5-bis-trifluoromethyl-phenyl)-1-(1H-indol-3-ylmethyl)-2-oxo-butyl]-amide
Show/Hide
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C28H31F6N3O2
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1
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| 1 |
IC50 = 0.6 nM
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CP0453341
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-3-piperidin-1-ylpropanamide
Show/Hide
|
C29H31F6N3O2
|
1
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| 1 |
IC50 = 0.6 nM
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CP0380069
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-3-dimethylamino-propan-1-one
Show/Hide
|
C26H30F6N2O2
|
1
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| 1 |
IC50 = 0.6 nM
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CP0498093
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3-[2-(4-Chloro-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C29H30ClN3O2
|
1
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| 1 |
IC50 = 0.6 nM
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CP0376401
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2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C29H27F6NO3S
|
1
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| 1 |
IC50 = 0.6 nM
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CP0530661
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-N-(pyridin-3-ylmethyl)cyclopentanamine
Show/Hide
|
C27H25F7N2O
|
1
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| 1 |
IC50 = 0.6 nM
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CP0467290
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5-(2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-phenyl-8-aza-bicyclo[3.2.1]octan-6-yl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
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C26H28F3N5O3
|
1
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| 1 |
IC50 = 0.61 nM
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CP0382453
|
2-(3,5-bis(trifluoromethyl)phenyl)-N-((1r,4r)-4-(3-oxo-4-phenylpiperazin-1-yl)-1-phenylcyclohexyl)propanamide
Show/Hide
|
C33H33F6N3O2
|
1
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| 1 |
IC50 = 0.62 nM
|
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CP0510448
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2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-N-methyl-acetamide
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
IC50 = 0.63 nM
|
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CP0213844
|
2-(3,5-Bis-trifluoromethyl-phenyl)-N-{4-[4-(4-fluoro-phenyl)-piperidin-1-yl]-1-phenyl-cyclohexyl}-propionamide
Show/Hide
|
C34H35F7N2O
|
1
|
| 1 |
IC50 = 0.63 nM
|
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CP0490248
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tert-butyl (2R,3S,4R)-4-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(hydroxymethyl)-3-phenylpyrrolidine-1-carboxylate
Show/Hide
|
C26H29F6NO4
|
1
|
| 1 |
IC50 = 0.63 nM
|
|
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CP0442315
|
(4R,5S)-5-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-4-(4-fluorophenyl)azepan-2-one
Show/Hide
|
C22H20F7NO2
|
1
|
| 1 |
IC50 = 0.64 nM
|
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CP0442580
|
N-[[2-cyclopropyloxy-5-(trifluoromethoxy)phenyl]methyl]-1-phenyl-6-(2H-tetrazol-5-yl)-8-azabicyclo[3.2.1]octan-2-amine
Show/Hide
|
C25H27F3N6O2
|
1
|
| 1 |
IC50 = 0.65 nM
|
|
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CP0382454
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3-(3,5-bis-trifluoromethyl-phenyl)-3-hydroxy-1-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-pyrrolidin-2-one
Show/Hide
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C32H36F6N2O3
|
1
|
| 1 |
IC50 = 0.66 nM
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|
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CP0427602
|
(1S,2R,5aR,7R,8aS,8bS)-7-amino-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
|
C26H25F7N2O2
|
2
|
| 1 |
IC50 = 0.66 nM
|
|
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| 2 |
IC50 = 13 nM
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CP0456463
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2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-N-(2-methoxyethyl)-N-methylacetamide
Show/Hide
|
C28H33F7N2O3
|
1
|
| 1 |
IC50 = 0.68 nM
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CP0434217
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(cyclohexanecarbonyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C28H30F6N2O2
|
1
|
| 1 |
IC50 = 0.68 nM
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CP0457029
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-4-(dimethylamino)butanamide
Show/Hide
|
C27H29F6N3O2
|
1
|
| 1 |
IC50 = 0.7 nM
|
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CP0467300
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-N-(pyridin-4-ylmethyl)cyclopentanamine
Show/Hide
|
C27H25F7N2O
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
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CP0500530
|
(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 1-[(3-chloro-phenyl)-phenyl-amide] 4-dibenzylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
Show/Hide
|
C45H48ClN5O4
|
1
|
| 1 |
IC50 = 0.7 nM
|
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CP0467835
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(pyrazine-3-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C26H22F6N4O2
|
1
|
| 1 |
IC50 = 0.74 nM
|
|
|
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CP0499587
|
(+/-)-trans-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methanol
Show/Hide
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C21H20F6O2
|
1
|
| 1 |
IC50 = 0.77 nM
|
|
|
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CP0383594
|
Bifunctional Peptide Ligand, 6 (TY023)
Show/Hide
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C59H69F6N9O11S
|
2
|
| 1 |
IC50 = 0.7762 nM
|
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| 2 |
Ki = 0.2 nM
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CP0555021
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-cyclopropylmethyl-piperazin-1-yl)-propan-1-one
Show/Hide
|
C26H29Cl2N3O
|
1
|
| 1 |
IC50 = 0.78 nM
|
|
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CP0490260
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[6-chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-propan-1-one
Show/Hide
|
C28H27Cl2N3O2
|
1
|
| 1 |
IC50 = 0.78 nM
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|
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CP0453366
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-5-furan-2-yl-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C34H33ClN2O3
|
1
|
| 1 |
IC50 = 0.79 nM
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CP0464141
|
(3R,4S)-N3-(3,5-bis(trifluoromethyl)benzyl)-N1-cyclohexyl-N3-methyl-4-phenylpyrrolidine-1,3-dicarboxamide
Show/Hide
|
C28H31F6N3O2
|
1
|
| 1 |
IC50 = 0.79 nM
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CP0284452
|
5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-ylmethyl]-2,4-dihydro-[1,2,4]triazole-3-thione
Show/Hide
|
C23H22F6N4OS
|
1
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| 1 |
IC50 = 0.8 nM
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CP0509791
|
5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-ethyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C22H22F6N4O2
|
1
|
| 1 |
IC50 = 0.8 nM
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CP0512364
|
3-(3,5-bis-trifluoromethyl-phenyl)-1-[4-(2-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-piperidin-2-one
Show/Hide
|
C33H38F6N2O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
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CP0407220
|
(5S)-5-[[[(1R,2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclopentyl]-methylamino]methyl]pyrrolidin-2-one
Show/Hide
|
C26H28F6N2O2
|
1
|
| 1 |
IC50 = 0.81 nM
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|
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CP0532440
|
(+/-)-trans-3-(3,5-bis(trifluoromethyl)benzyloxy)-N-methyl-2-phenylcyclopentanamine
Show/Hide
|
C21H21F6NO
|
1
|
| 1 |
IC50 = 0.83 nM
|
|
|
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CP0434215
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(pyrimidine-2-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C26H22F6N4O2
|
1
|
| 1 |
IC50 = 0.84 nM
|
|
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|
CP0376466
|
2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(4-hydroxy-piperidin-1-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
|
C28H32F6N2O2
|
1
|
| 1 |
IC50 = 0.85 nM
|
|
|
|
CP0042368
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidine
Show/Hide
|
C20H19F6NO
|
2
|
| 1 |
IC50 = 0.87 nM
|
|
|
| 2 |
IC50 = 1 nM
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|
|
|
CP0243781
|
5-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C23H22F6N4O3
|
1
|
| 1 |
IC50 = 0.88 nM
|
|
|
|
CP0423172
|
3-[5-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C28H27Cl2N3O2
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0506870
|
3-(2-Methoxy-5-trifluoromethoxy-phenyl)-6-phenyl-7-(1H-[1,2,4]triazol-3-ylmethyl)-1-oxa-7-aza-spiro[4.5]decane
Show/Hide
|
C25H27F3N4O3
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0525822
|
(+/-)-trans-methyl-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylcarbamate
Show/Hide
|
C22H21F6NO3
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0454636
|
2-Benzhydryl-3-(3-methyl-5-trimethylsilanyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C31H39NOSi
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0397669
|
1-Aza-bicyclo[2.2.2]octane-4-carboxylic acid [(S)-4-(3,5-bis-trifluoromethyl-phenyl)-1-(1H-indol-3-ylmethyl)-2-oxo-butyl]-amide
Show/Hide
|
C29H29F6N3O2
|
3
|
| 1 |
IC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 1 nM
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|
|
| 3 |
IC50 = 8 nM
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CP0285637
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-(1H-imidazol-4-ylmethyl)-2-phenyl-piperidine
Show/Hide
|
C24H23F6N3O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0516714
|
4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-methyl-4-phenyl-piperidine
Show/Hide
|
C22H23F6NO
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0402909
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-(5-chloro-1-methyl-2-pyridin-3-yl-1H-indol-3-yl)-propan-1-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0422170
|
(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-phenyl-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C30H24F7NO2
|
2
|
| 1 |
IC50 = 0.93 nM
|
|
|
| 2 |
IC50 = 89.5 nM
|
|
|
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CP0492393
|
1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-pyridin-4-yl-ethanone
Show/Hide
|
C28H26F6N2O2
|
1
|
| 1 |
IC50 = 0.94 nM
|
|
|
|
CP0062034
|
4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C21H21F6NO
|
2
|
| 1 |
IC50 = 0.95 nM
|
|
|
| 2 |
IC50 = 1 nM
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|
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CP0394375
|
2-(((1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentyl)(methyl)amino)-1-(4-methylpiperazin-1-yl)ethanone
Show/Hide
|
C29H34F7N3O2
|
1
|
| 1 |
IC50 = 0.95 nM
|
|
|
|
CP0217134
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-[1,3,4]oxadiazol-2-ylmethyl-2-phenyl-piperidine
Show/Hide
|
C23H21F6N3O2
|
1
|
| 1 |
IC50 = 0.97 nM
|
|
|
|
CP0461778
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-(2-hydroxy-ethyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C30H31Cl2N3O3
|
1
|
| 1 |
IC50 = 0.97 nM
|
|
|
|
CP0434219
|
(3S,4R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-acetylpiperidine-4-carbonyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C29H31F6N3O3
|
1
|
| 1 |
IC50 = 0.97 nM
|
|
|
|
CP0151784
|
2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-acetamide
Show/Hide
|
C22H22F6N2O2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 1.3 nM
|
|
|
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CP0194736
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-oxazol-4-ylmethyl-2-phenyl-piperidine
Show/Hide
|
C24H22F6N2O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0383428
|
2-benzylamino-3-(3,4-dichlorobenzyloxy)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
|
C30H33Cl2N3O4S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0422276
|
1'N-[1-[3,5-di(trifluoromethyl)benzyl(methyl)carbamoyl]-2-(1H-3-indolyl)-(1S)-ethyl]-1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
|
C35H35F6N5O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0290532
|
2-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-phenyl-piperidine
Show/Hide
|
C21H21F6NO
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0258042
|
3-[2-(4-Bromo-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C29H30BrN3O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0406358
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3-methoxyphenyl)ethyl]piperazine
Show/Hide
|
C22H24F6N2O2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0393714
|
(6S,7R,7aR)-7-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-(4-fluorophenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
|
C22H18F7NO3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0514323
|
2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C24H23F6N5O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0467331
|
2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-(4-fluorophenyl)-8-aza-bicyclo[3.2.1]octane-6-carboxylic acid
Show/Hide
|
C25H26F4N2O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0243352
|
(2S,3S)-2-Benzhydryl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C29H33NO
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 2 nM
|
|
|
|
CP0373888
|
(2S)-1-[(4S,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carbonyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C57H64F6N10O9S2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
Ki = 0.52 nM
|
|
|
|
CP0459002
|
N-[4-[(1S,2R)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-(4-fluorophenyl)-5-oxo-2,3,8,8a-tetrahydro-1H-indolizin-7-yl]phenyl]methanesulfonamide
Show/Hide
|
C31H27F7N2O4S
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 54 nM
|
|
|
|
CP0383837
|
2-[(2S,3S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-3-phenyl-morpholin-4-yl]-acetamide
Show/Hide
|
C21H20F6N2O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0404228
|
1-[5-[[5-(4-fluorophenyl)-9-[2-(trifluoromethyl)phenyl]-1,7-dioxa-4-azaspiro[5.5]undecan-4-yl]methyl]-2H-triazol-4-yl]-N,N-dimethylmethanamine
Show/Hide
|
C27H31F4N5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0459714
|
4-((1r,4r)-4-(3-(3,5-bis(trifluoromethyl)phenyl)-2-oxopyrrolidin-1-yl)-4-phenylcyclohexyl)-1-phenylpiperazin-2-one
Show/Hide
|
C34H33F6N3O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0407219
|
(+/-)-trans-3-(3,5-bis(trifluoromethyl)benzyloxy)-N-((4H-1,2,4-triazol-3-yl)methyl)-N-methyl-2-phenylcyclopentanamine
Show/Hide
|
C24H24F6N4O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0402044
|
(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(2-methoxypyridin-4-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
|
C30H25F7N2O3
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 44 nM
|
|
|
|
CP0524611
|
1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-4-dimethylamino-butan-1-one
Show/Hide
|
C27H32F6N2O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0511236
|
2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(4-methyl-piperidin-1-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
|
C29H34F6N2O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0378382
|
tert-butyl (2S,3R,4S)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Show/Hide
|
C26H28F7NO4
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0376376
|
2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-6-(1-methyl-1H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C25H25F6N5O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0502484
|
2-(2-cyclopropoxy-5-(trifluoromethoxy)benzylamino)-1-(4-fluorophenyl)-N-(methylsulfonyl)-8-aza-bicyclo[3.2.1]octane-6-carboxamide
Show/Hide
|
C26H29F4N3O5S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0405357
|
(1S,2R,5aR,7R,8aS,8bS)-7-(benzylamino)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C33H31F7N2O2
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2
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| 1 |
IC50 = 1.2 nM
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| 2 |
IC50 = 13 nM
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CP0543912
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1-[2-[(3-bromo-5-iodophenyl)methoxy]-1-phenylethyl]piperazine
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C19H22BrIN2O
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1
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| 1 |
IC50 = 1.259 nM
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CP0430273
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-phenylamino-piperidin-1-yl)-propan-1-one
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C29H29Cl2N3O
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1
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| 1 |
IC50 = 1.3 nM
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CP0424275
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(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-5-trifluoromethyl-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
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C22H23F4NO3
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1
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| 1 |
IC50 = 1.3 nM
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CP0393715
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(6S,7R,7aS)-7-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-phenyl-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
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C22H19F6NO3
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1
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| 1 |
IC50 = 1.3 nM
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CP0394152
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(1R,2S,3S)-3-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentanamine
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C21H20F7NO
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1
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| 1 |
IC50 = 1.3 nM
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CP0453511
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(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-methyl-1-phenyl-N-(1H-1,2,4-triazol-5-ylmethyl)ethanamine
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C21H20F6N4O
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1
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| 1 |
IC50 = 1.4 nM
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CP0049105
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(SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
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C63H98N18O13S
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4
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| 1 |
IC50 = 1.4 nM
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| 2 |
IC50 = 1.5 nM
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| 3 |
IC50 = 1.7 nM
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| 4 |
Ki = 1.6 nM
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CP0484580
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1-[5-[[5-(4-fluorophenyl)-9-[2-(trifluoromethoxy)phenyl]-1,7-dioxa-4-azaspiro[5.5]undecan-4-yl]methyl]-2H-triazol-4-yl]-N,N-dimethylmethanamine
Show/Hide
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C27H31F4N5O3
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1
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| 1 |
IC50 = 1.4 nM
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CP0516259
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N-[(1R,2S,3S)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(4-fluorophenyl)cyclopentyl]-N-methylpyrazin-2-amine
Show/Hide
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C26H24F7N3O
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1
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| 1 |
IC50 = 1.4 nM
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CP0374694
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(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 1-[(3-chloro-phenyl)-phenyl-amide] 4-dipentylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
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C41H56ClN5O4
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1
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| 1 |
IC50 = 1.4 nM
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CP0036095
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-acetamido-3-(1H-indol-3-yl)propanoate
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C22H18F6N2O3
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9
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| 1 |
IC50 = 1.479 nM
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| 2 |
IC50 = 1.585 nM
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| 3 |
IC50 = 1.6 nM
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| 4 |
IC50 = 2.5 nM
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| 5 |
IC50 = 3.3 nM
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| 6 |
IC50 = 8.1 nM
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| 7 |
IC50 = 398.11 nM
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| 8 |
Ki = 0.73 nM
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| 9 |
Ki = 134 nM
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CP0511543
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5-({[(S)-2-(3,5-Dichloro-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
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C19H20Cl2N4O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0454772
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3-[2-(4-Methoxy-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C30H33N3O3
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1
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| 1 |
IC50 = 1.5 nM
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CP0382452
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4-((1r,4r)-4-(3-(3,5-bis(trifluoromethyl)phenyl)-2-oxopiperidin-1-yl)-4-phenylcyclohexyl)-1-phenylpiperazin-2-one
Show/Hide
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C35H35F6N3O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0392968
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(6S,7R,7aR)-7-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-6-phenyl-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]oxazol-3-one
Show/Hide
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C22H19F6NO3
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1
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| 1 |
IC50 = 1.5 nM
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CP0428081
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2-(3,5-bis(trifluoromethyl)benzyloxy)-6-fluoro-6-(2-methyl-2H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
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C24H22F7N5O
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1
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| 1 |
IC50 = 1.5 nM
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CP0408373
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(5S)-5-[[[(1R,2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclopentyl]amino]methyl]pyrrolidin-2-one
Show/Hide
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C25H26F6N2O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0427606
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(1S,2R,5aR,7R,8aS,8bS)-7-amino-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)octahydrocyclopenta[a]pyrrolizin-5(5aH)-one
Show/Hide
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C26H25F7N2O2
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2
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| 1 |
IC50 = 1.5 nM
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| 2 |
IC50 = 47 nM
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CP0402530
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3-chlorophenyl)ethyl]piperazine
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C21H21ClF6N2O
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2
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| 1 |
IC50 = 1.585 nM
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| 2 |
Ki = 1.585 nM
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CP0514597
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(2-chlorophenyl)ethyl]piperazine
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C21H21ClF6N2O
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2
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| 1 |
IC50 = 1.585 nM
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| 2 |
Ki = 1.585 nM
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CP0464756
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methyl 2-[(2S,3S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-3-phenylmorpholin-4-yl]acetate
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C22H21F6NO4
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1
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| 1 |
IC50 = 1.6 nM
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CP0440227
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(4-oxo-piperidin-1-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C28H30F6N2O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0391647
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2-Acetylamino-3-(1H-indol-3-yl)-propionic acid 3,5-bis-trifluoromethyl-benzyl ester
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C22H18F6N2O3
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1
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| 1 |
IC50 = 1.6 nM
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CP0441819
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2-(3,4-dichlorobenzylamino)-3-(3,4-dichlorobenzyloxy)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
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C30H31Cl4N3O4S
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1
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| 1 |
IC50 = 1.7 nM
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CP0518376
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5-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C24H24F6N4O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0439552
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-pyridin-2-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C35H34ClN3O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0402045
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-7-(3-isopropyl-1,2,4-oxadiazol-5-yl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C29H26F7N3O3
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2
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| 1 |
IC50 = 1.7 nM
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| 2 |
IC50 = 72 nM
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CP0500411
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-3-(dimethylamino)propanamide
Show/Hide
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C26H27F6N3O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0453049
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3-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-propionamide
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C23H24F6N2O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0397736
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-pyridin-2-yl-ethanone
Show/Hide
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C28H26F6N2O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0525388
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4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-1-(2H-[1,2,4]triazol-3-ylmethyl)-piperidine
Show/Hide
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C24H24F6N4O
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1
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| 1 |
IC50 = 1.8 nM
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CP0538225
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1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-2-pyridin-3-yl-ethanone
Show/Hide
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C28H26F6N2O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0430411
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4-((1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-5-oxo-1,2,3,5,8,8a-hexahydroindolizin-7-yl)benzonitrile
Show/Hide
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C31H23F7N2O2
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2
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| 1 |
IC50 = 1.8 nM
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| 2 |
IC50 = 53 nM
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CP0496748
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benzyl N-(2-amino-2-oxoethyl)-N-[2-[[(2S,4S)-1-[(3-chlorophenyl)-phenylcarbamoyl]-4-(dipentylcarbamoyl)piperidine-2-carbonyl]amino]ethyl]carbamate
Show/Hide
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C42H55ClN6O6
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1
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| 1 |
IC50 = 1.8 nM
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CP0501240
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(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
Show/Hide
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C41H57N5O4
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1
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| 1 |
IC50 = 1.8 nM
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CP0542892
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(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 2-({2-[carbamoylmethyl-(2-methoxy-benzyl)-amino]-ethyl}-amide) 4-dipentylamide 1-diphenylamide
Show/Hide
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C42H58N6O5
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1
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| 1 |
IC50 = 1.8 nM
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CP0394642
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(+-)-trans-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)-N-methylmethanamine
Show/Hide
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C22H23F6NO
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1
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| 1 |
IC50 = 1.9 nM
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CP0433496
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(+/-)-trans-2-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methylamino)acetamide
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
IC50 = 1.9 nM
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CP0515784
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(+/-)-trans-2-(((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)(methyl)amino)acetamide
Show/Hide
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C24H26F6N2O2
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1
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| 1 |
IC50 = 1.9 nM
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CP0458989
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(1S,2R)-7-(1-benzyl-1H-pyrazol-4-yl)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C34H28F7N3O2
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2
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| 1 |
IC50 = 1.9 nM
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| 2 |
IC50 = 66 nM
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CP0372167
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(S)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)-N-((S)-1-((S)-1-(3,4-dimethoxybenzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-yl)pyrrolidine-2-carboxamide
Show/Hide
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C62H82N10O11
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2
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| 1 |
IC50 = 1.995 nM
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| 2 |
Ki = 0.95 nM
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CP0183634
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-2-morpholin-4-ylacetamide
Show/Hide
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C27H27F6N3O3
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3
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 3.5 nM
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| 3 |
IC50 = 4 nM
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CP0399927
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5-({[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-propyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C23H24F6N4O2
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1
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| 1 |
IC50 = 2 nM
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CP0463787
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-[4-(2,2-dimethyl-propyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C27H33Cl2N3O
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1
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| 1 |
IC50 = 2 nM
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CP0422295
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(+/-)-trans-5-((((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
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C25H26F6N4O2
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1
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| 1 |
IC50 = 2 nM
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CP0493311
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(1S,2R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1,7-bis(4-fluorophenyl)-2,3,8,8a-tetrahydroindolizin-5(1H)-one
Show/Hide
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C30H23F8NO2
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 100 nM
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CP0431982
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Bifunctional Peptide Ligand, 7 (TY018)
Show/Hide
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C60H71F6N9O10
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2
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| 1 |
IC50 = 2.042 nM
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| 2 |
Ki = 0.6 nM
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CP0448373
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-[4-(2-oxo-1-oxa-8-aza-spiro[4.5]dec-8-yl)-1-phenyl-cyclohexyl]-propionamide
Show/Hide
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C32H36F6N2O3
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1
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| 1 |
IC50 = 2.1 nM
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CP0502483
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N-[[2-chloro-5-(trifluoromethoxy)phenyl]methyl]-1-phenyl-8-azabicyclo[3.2.1]octan-2-amine
Show/Hide
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C21H22ClF3N2O
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1
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| 1 |
IC50 = 2.1 nM
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CP0515783
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(+/-)-cis-2-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)(methyl)amino)acetamide
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
IC50 = 2.1 nM
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CP0372166
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(S)-N-((S)-1-((S)-3-(1H-indol-3-yl)-1-oxo-1-(3-(trifluoromethyl)benzylamino)propan-2-ylamino)-4-methyl-1-oxopentan-2-yl)-1-((2S,5S,11R,14S)-14-amino-5-benzyl-2-butyl-15-(4-hydroxy-2,6-dimethylphenyl)-11-methyl-4,7,10,13-tetraoxo-3,6,9,12-tetraazapentadecane)pyrrolidine-2-carboxamide
Show/Hide
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C61H77F3N10O9
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2
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| 1 |
IC50 = 2.188 nM
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| 2 |
Ki = 1 nM
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CP0183220
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N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]acetamide
Show/Hide
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C23H20F6N2O2
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3
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| 1 |
IC50 = 2.2 nM
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| 2 |
IC50 = 3.1 nM
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| 3 |
IC50 = 10 nM
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CP0495847
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5-({[(S)-2-(3-Chloro-5-methyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-methyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C20H23ClN4O2
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1
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| 1 |
IC50 = 2.2 nM
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CP0400973
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1-(4-Benzyl-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C30H30Cl2N2O
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1
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| 1 |
IC50 = 2.2 nM
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CP0542513
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2-[1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-acetamide
Show/Hide
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C26H30N2O2
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1
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| 1 |
IC50 = 2.2 nM
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CP0507028
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-pyrrol-1-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
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C34H34ClN3O2
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1
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| 1 |
IC50 = 2.3 nM
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CP0404802
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(2S,3S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-3-phenyl-morpholine
Show/Hide
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C19H17F6NO2
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1
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| 1 |
IC50 = 2.4 nM
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CP0505436
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5-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamino]-methyl}-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
|
C20H18F6N4O2
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1
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| 1 |
IC50 = 2.4 nM
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CP0439057
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4-(3-tert-Butyl-5-methyl-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
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C24H33NO
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1
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| 1 |
IC50 = 2.4 nM
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CP0467625
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-(1-phenyl-4-piperidin-1-yl-cyclohexyl)-propionamide
Show/Hide
|
C28H32F6N2O
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1
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| 1 |
IC50 = 2.4 nM
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CP0453041
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(+/-)-trans-4-(((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)(methyl)amino)methyl)-1H-imidazol-2(3H)-one
Show/Hide
|
C25H25F6N3O2
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1
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| 1 |
IC50 = 2.4 nM
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CP0502002
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1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[5-chloro-2-(4-chloro-phenyl)-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl]-propan-1-one
Show/Hide
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C29H29Cl2N3O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0394173
|
Bifunctional Peptide Ligand, 4 (TY004)
Show/Hide
|
C60H71F6N9O10
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2
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| 1 |
IC50 = 2.692 nM
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| 2 |
Ki = 0.8 nM
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|
|
|
CP0510095
|
4-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-butyramide
Show/Hide
|
C24H26F6N2O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0536132
|
(6R,7S,7aR)-2-benzyl-6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-7-(4-fluorophenyl)-5,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]imidazol-3-one
Show/Hide
|
C29H25F7N2O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0374862
|
(+-)-trans-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methanamine
Show/Hide
|
C21H21F6NO
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0453080
|
(+/-)-trans-1-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)-3-methylurea
Show/Hide
|
C22H22F6N2O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0503399
|
(+/-)-trans-2-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)(methyl)amino)acetamide
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0498622
|
methyl 2-[(2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidin-1-yl]acetate
Show/Hide
|
C23H23F6NO3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0528856
|
4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-(2-methyl-thiazol-4-ylmethyl)-4-phenyl-piperidine
Show/Hide
|
C26H26F6N2OS
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0542138
|
(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(5-isopropyl-2-methoxy-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
|
C24H30FNO3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0501989
|
2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-6-(phenylsulfonyl)-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C28H25F6NO3S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0394172
|
Bifunctional Peptide Ligand, 8 (TY019)
Show/Hide
|
C61H73F6N9O10
|
2
|
| 1 |
IC50 = 2.884 nM
|
|
|
| 2 |
Ki = 0.71 nM
|
|
|
|
CP0374847
|
4-(3-Bromo-5-methyl-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C20H24BrNO
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0466983
|
4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-isopropyl-4-phenyl-piperidine
Show/Hide
|
C24H27F6NO
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0383035
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-cyclohexylmethyl-piperazin-1-yl)-propan-1-one
Show/Hide
|
C29H35Cl2N3O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0555275
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-(5-chloro-1-methyl-2-pyridin-2-yl-1H-indol-3-yl)-propan-1-one
Show/Hide
|
C29H30ClN3O2
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0383437
|
Bifunctional Peptide Ligand, 1 (TY003)
Show/Hide
|
C63H69F6N9O10
|
2
|
| 1 |
IC50 = 2.951 nM
|
|
|
| 2 |
Ki = 0.88 nM
|
|
|
|
CP0425148
|
2-(3,5-bis(trifluoromethyl)benzyloxy)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C22H21F6NO
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0467291
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-phenyl-8-azabicyclo[3.2.1]octan-2-amine
Show/Hide
|
C22H22F6N2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0525480
|
methyl 2-[4-[[3,5-bis(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidin-1-yl]acetate
Show/Hide
|
C24H25F6NO3
|
1
|
| 1 |
IC50 = 3.1 nM
|
|
|
|
CP0438470
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(2,3-difluorophenyl)ethyl]piperazine
Show/Hide
|
C21H20F8N2O
|
2
|
| 1 |
IC50 = 3.162 nM
|
|
|
| 2 |
Ki = 3.162 nM
|
|
|
|
CP0457209
|
1-[(1S)-2-[(3,5-dibromophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
|
C19H22Br2N2O
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0492211
|
1-[(1S)-2-[(3,5-dichlorophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
|
C19H22Cl2N2O
|
1
|
| 1 |
IC50 = 3.162 nM
|
|
|
|
CP0441784
|
2-benzylamino-5-(3,4-dichlorophenyl)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-pentanone
Show/Hide
|
C31H35Cl2N3O3S
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0521908
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-piperidin-1-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C35H40ClN3O2
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0431981
|
Bifunctional Peptide Ligand, 3 (TY006)
Show/Hide
|
C56H63F6N9O10
|
2
|
| 1 |
IC50 = 3.388 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0434214
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(pyrimidine-4-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C26H22F6N4O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0501103
|
(+/-)-trans-1-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)urea
Show/Hide
|
C21H20F6N2O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0449311
|
(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 2-{[2-(carbamoylmethyl-amino)-ethyl]-amide} 1-[(3-chloro-phenyl)-phenyl-amide] 4-dipentylamide
Show/Hide
|
C34H49ClN6O4
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0457153
|
tert-butyl (2S,3R,4S)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate
Show/Hide
|
C26H29F6NO4
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0477459
|
(2R,3R)-2-benzhydryl-N-(2-iodophenyl)-1-azabicyclo[2.2.2]octan-3-amine
Show/Hide
|
C26H27IN2
|
2
|
| 1 |
IC50 = 3.6 nM
|
|
|
| 2 |
Ki = 2.6 nM
|
|
|
|
CP0455330
|
2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-cyclohexyl]-N-pyridin-3-ylmethyl-acetamide
Show/Hide
|
C29H28F6N2O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0477832
|
(3R,4R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-acetylpiperidine-4-carbonyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C29H31F6N3O3
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0402487
|
N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-2-(1H-imidazol-5-yl)acetamide
Show/Hide
|
C26H22F6N4O2
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0459308
|
(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 2-({2-[carbamoylmethyl-(2-methoxy-benzyl)-amino]-ethyl}-amide) 1-[(3-chloro-phenyl)-phenyl-amide] 4-dipentylamide
Show/Hide
|
C42H57ClN6O5
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0373195
|
(2S)-1-[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]-N-[(2S)-1-[[(2S)-1-(benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C57H72N10O9S
|
2
|
| 1 |
IC50 = 3.981 nM
|
|
|
| 2 |
Ki = 3.2 nM
|
|
|
|
CP0515044
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(piperidine-4-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
|
C27H29F6N3O2
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0372408
|
(S)-2-((S)-2-(2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)acetamido)-3-phenylpropanamido)-N-((S)-1-((S)-1-((S)-1-(3,5-bis(trifluoromethyl)benzylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-ylamino)-4-methyl-1-oxopentan-2-ylamino)-1-oxo-3-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yloxy)propan-2-yl)hexanamide
Show/Hide
|
C64H80F6N10O15
|
2
|
| 1 |
IC50 = 4.169 nM
|
|
|
| 2 |
Ki = 1.8 nM
|
|
|
|
CP0529883
|
2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-phenyl-8-aza-bicyclo[3.2.1]octane
Show/Hide
|
C23H23F6NO
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0464334
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-phenylimidazo[1,5-a]quinoline-4-carboxamide
Show/Hide
|
C28H19F6N3O
|
1
|
| 1 |
IC50 = 4.3 nM
|
|
|
|
CP0378383
|
tert-butyl (2S,3S,4R)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-2-(hydroxymethyl)pyrrolidine-1-carboxylate
Show/Hide
|
C26H28F7NO4
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0894587
|
[1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethyl]-dimethyl-amine
Show/Hide
|
C26H31NO
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0157374
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-acetylpiperidine-4-carbonyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C29H31F6N3O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0492394
|
4-(3,5-Dichloro-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C19H21Cl2NO
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0408372
|
(+/-)-cis-5-((((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C25H26F6N4O2
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0521871
|
N-[2-[4-[(2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]propanoyl]piperazin-1-yl]phenyl]methanesulfonamide
Show/Hide
|
C28H32Cl2N4O4S
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0503241
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,2-dimethyl-6-(4-methylpiperazin-1-yl)-4-phenylpyridine-3-carboxamide
Show/Hide
|
C28H28F6N4O
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0501014
|
3-[6-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C28H27Cl2N3O2
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0532439
|
(+/-)-trans-5-(((2-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)ethyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C26H28F6N4O2
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0457252
|
N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-2-(dimethylamino)acetamide
Show/Hide
|
C25H25F6N3O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0483631
|
(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenyl-N-(1H-1,2,4-triazol-5-ylmethyl)ethanamine
Show/Hide
|
C20H18F6N4O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0500660
|
(+/-)-trans-3-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)-1,1-dimethylurea
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0525823
|
(+/-)-trans-1-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)piperidine
Show/Hide
|
C26H29F6NO
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0495729
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(2-fluorophenyl)ethyl]piperazine
Show/Hide
|
C21H21F7N2O
|
2
|
| 1 |
IC50 = 5.012 nM
|
|
|
| 2 |
Ki = 5.012 nM
|
|
|
|
CP0540320
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3,4-dichlorophenyl)ethyl]piperazine
Show/Hide
|
C21H20Cl2F6N2O
|
2
|
| 1 |
IC50 = 5.012 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0541809
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazine
Show/Hide
|
C21H22F6N2O
|
2
|
| 1 |
IC50 = 5.012 nM
|
|
|
| 2 |
Ki = 1.585 nM
|
|
|
|
CP0448803
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-isopropyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C31H33Cl2N3O2
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0374856
|
(+/-)-trans-4-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylamino)methyl)-1H-imidazol-2(3H)-one
Show/Hide
|
C24H23F6N3O2
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0531446
|
1-[4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-4-phenyl-piperidin-1-yl]-ethanone
Show/Hide
|
C23H23F6NO2
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0374859
|
(+/-)-cis-methyl-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylcarbamate
Show/Hide
|
C22H21F6NO3
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0398645
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-pyridin-4-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C35H34ClN3O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0439804
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-pyridin-3-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C35H34ClN3O2
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0195389
|
(2S)-3-[(3,5-dimethylphenyl)methoxy]-N,N-dimethyl-1,1-diphenylpropan-2-amine
Show/Hide
|
C26H31NO
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0397245
|
(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 2-[(3-diethylamino-propyl)-amide] 4-dipentylamide 1-diphenylamide
Show/Hide
|
C37H57N5O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0503664
|
3-(5-Chloro-2-phenyl-1H-indol-3-yl)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C28H28ClN3O2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0441630
|
4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-methanesulfonyl-4-phenyl-piperidine
Show/Hide
|
C22H23F6NO3S
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0196186
|
2-{[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethyl]-methyl-amino}-acetamide
Show/Hide
|
C20H20F6N2O2
|
1
|
| 1 |
IC50 = 5.8 nM
|
|
|
|
CP0383405
|
1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(5-methyl-2-phenyl-1H-indol-3-yl)-propan-1-one
Show/Hide
|
C29H31N3O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0529895
|
3-(3,5-bis(trifluoromethyl)phenyl)-1-((1r,4r)-4-(dimethylamino)-1-phenylcyclohexyl)pyrrolidin-2-one
Show/Hide
|
C26H28F6N2O
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0456435
|
(+/-)-trans-methyl-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl(methyl)carbamate
Show/Hide
|
C23H23F6NO3
|
1
|
| 1 |
IC50 = 6.2 nM
|
|
|
|
CP0454595
|
3-[2-(4-tert-Butyl-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C33H39N3O2
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0376287
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-5-morpholin-4-yl-1H-indol-3-yl]-propan-1-one
Show/Hide
|
C34H38ClN3O3
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0455451
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(2-methoxyphenyl)ethyl]piperazine
Show/Hide
|
C22H24F6N2O2
|
2
|
| 1 |
IC50 = 6.31 nM
|
|
|
| 2 |
Ki = 6.31 nM
|
|
|
|
CP0453443
|
3-(2-Methoxy-phenyl)-6-phenyl-1-oxa-7-aza-spiro[4.5]decane
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C21H25NO2
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1
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| 1 |
IC50 = 6.5 nM
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CP0406294
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2-benzylamino-3-(4-chlorobenzyloxy)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
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C30H34ClN3O4S
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1
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| 1 |
IC50 = 6.6 nM
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CP0429223
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[(1S,2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclohexyl]methylurea
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C23H24F6N2O2
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1
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| 1 |
IC50 = 6.7 nM
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CP0404662
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3-[(3,5-dimethylphenyl)methoxy]-N-methyl-1,1-diphenylpropan-2-amine
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C25H29NO
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1
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| 1 |
IC50 = 6.8 nM
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CP0543878
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4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-phenethyl-4-phenyl-piperidine
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C29H29F6NO
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1
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| 1 |
IC50 = 6.9 nM
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CP0378360
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2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-cyclohexyl]-N-pyridin-4-ylmethyl-acetamide
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C29H28F6N2O2
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1
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| 1 |
IC50 = 7 nM
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CP0501104
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(+/-)-trans-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentanecarboxamide
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C21H19F6NO2
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1
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| 1 |
IC50 = 7.2 nM
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CP0522340
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(+/-)-cis-3-(3,5-bis(trifluoromethyl)benzyloxy)-N-methyl-2-phenylcyclopentanamine
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C21H21F6NO
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1
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| 1 |
IC50 = 7.2 nM
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CP0382815
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(2S)-1-[(4R,7S,13S)-13-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carbonyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C57H64F6N10O9S2
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2
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| 1 |
IC50 = 7.244 nM
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| 2 |
Ki = 3.7 nM
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CP0430423
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4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-1-[1,2,4]oxadiazol-3-ylmethyl-4-phenyl-piperidine
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C24H23F6N3O2
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1
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| 1 |
IC50 = 7.3 nM
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CP0475731
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3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-(cyclohexyl-phenyl-methyl)-1-aza-bicyclo[2.2.2]octane
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C29H33F6NO
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1
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| 1 |
IC50 = 7.5 nM
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CP0454773
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3-(2-Biphenyl-4-yl-5-methyl-1H-indol-3-yl)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C35H35N3O2
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1
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| 1 |
IC50 = 7.6 nM
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CP0542380
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2-benzylamino-3-(2-chlorobenzyloxy)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
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C30H34ClN3O4S
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1
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| 1 |
IC50 = 7.7 nM
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CP0472159
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tert-butyl (2S,3S,4R)-3-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-2-(hydroxymethyl)-4-phenylpyrrolidine-1-carboxylate
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C26H29F6NO4
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1
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| 1 |
IC50 = 7.8 nM
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CP0433497
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(+/-)-cis-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentanamine
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C20H19F6NO
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1
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| 1 |
IC50 = 7.9 nM
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CP0497967
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1-[2-[(3,5-dibromo-2-methoxyphenyl)methoxy]-1-phenylethyl]piperazine
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C20H24Br2N2O2
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2
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| 1 |
IC50 = 7.943 nM
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| 2 |
Ki = 7.943 nM
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CP0214213
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2-[(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamino]-acetamide
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C19H18F6N2O2
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1
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| 1 |
IC50 = 8 nM
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CP0565853
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3-[2-(3-Methoxy-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C30H33N3O3
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1
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| 1 |
IC50 = 8 nM
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CP0403566
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(S)-Piperazine-1,2,4-tricarboxylic acid 1-[(3-chloro-phenyl)-phenyl-amide] 2-[(3-diethylamino-propyl)-amide] 4-dipentylamide
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C36H55ClN6O3
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1
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| 1 |
IC50 = 8 nM
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CP0522342
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(+/-)-trans-4-((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)morpholine
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C25H27F6NO2
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1
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| 1 |
IC50 = 8.2 nM
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CP0503378
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(+/-)-cis-2-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylamino)acetamide
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C22H22F6N2O2
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1
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| 1 |
IC50 = 8.3 nM
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CP0496629
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3-[2-(4-Chloro-phenyl)-5-trifluoromethoxy-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C29H27ClF3N3O3
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1
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| 1 |
IC50 = 8.9 nM
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CP0496546
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(S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-{[2-(2-methoxy-benzylamino)-ethyl]-amide}
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C39H54N6O4
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1
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| 1 |
IC50 = 9 nM
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CP0496652
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(S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
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C40H56N6O4
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1
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| 1 |
IC50 = 9 nM
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CP0529901
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2-(3,5-bis(trifluoromethyl)benzyloxy)-6-(1-methyl-1H-tetrazol-5-yl)-1-phenyl-8-aza-bicyclo[3.2.1]octane
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C24H23F6N5O
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1
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| 1 |
IC50 = 9 nM
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CP0457348
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-phenyl-[1,2,4]triazolo[4,3-a]quinoline-4-carboxamide
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C27H18F6N4O
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1
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| 1 |
IC50 = 9 nM
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CP0150724
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4-(3,5-Dimethyl-benzyloxymethyl)-4-phenyl-piperidine
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C21H27NO
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1
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| 1 |
IC50 = 9.1 nM
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CP0445220
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1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethylamine
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C24H27NO
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1
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| 1 |
IC50 = 9.3 nM
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CP0493880
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1-(3-Bromo-5-methyl-benzyloxymethyl)-2,2-diphenyl-ethylamine
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C23H24BrNO
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1
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| 1 |
IC50 = 9.7 nM
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CP0503379
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(+/-)-cis-1-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)urea
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C21H20F6N2O2
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1
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| 1 |
IC50 = 9.8 nM
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CP0438548
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1'N-[1-[3,5-dimethylbenzyl(methyl)carbamoyl]-2-(1H-3-indolyl)-(1S)-ethyl]-1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1'-carboxamide
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C35H41N5O2S
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1
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| 1 |
IC50 = 10 nM
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CP0437393
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(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-[(1-methyltetrazol-5-yl)methyl]-1-phenylethanamine
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C20H19F6N5O
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1
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| 1 |
IC50 = 10 nM
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CP0465385
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(3S,5S,10S)-10-(5-Fluoro-2-methoxy-phenyl)-5-(4-fluoro-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
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C21H23F2NO3
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1
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| 1 |
IC50 = 10 nM
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CP0409706
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Bifunctional Peptide Ligand, 2 (TY007)
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C63H69F6N9O10
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2
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| 1 |
IC50 = 10 nM
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| 2 |
Ki = 3 nM
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CP0492309
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N-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-N-methyl-3,3-diphenylpropanamide
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C26H23F6NO
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1
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| 1 |
IC50 = 10 nM
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CP0403542
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1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamine
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C24H21F6NO
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1
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| 1 |
IC50 = 10.7 nM
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CP0464418
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diethylamino-ethyl)-amide] 4-dipentylamide 1-diphenylamide
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C35H54N6O3
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1
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| 1 |
IC50 = 11 nM
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CP0496744
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3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-5-methyl-oxazolidine-2,4-dione
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C22H16F6N2O3
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1
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| 1 |
IC50 = 11 nM
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CP0448446
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3-(3-chlorobenzyloxy)-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
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C30H32Cl3N3O4S
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1
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| 1 |
IC50 = 11 nM
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CP0434218
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(3R,4S)-tert-butyl 3-((3,5-bis(trifluoromethyl)benzyl)(methyl)carbamoyl)-4-phenylpyrrolidine-1-carboxylate
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C26H28F6N2O3
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1
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| 1 |
IC50 = 11 nM
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CP0509471
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N-[3-[(3,5-dimethylphenyl)methoxy]-1,1-diphenylpropan-2-yl]formamide
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C25H27NO2
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1
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| 1 |
IC50 = 11 nM
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CP0419224
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1-(3,5-Dichloro-benzyloxymethyl)-2,2-diphenyl-ethylamine
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C22H21Cl2NO
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1
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| 1 |
IC50 = 11.3 nM
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CP0511147
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3-benzyloxy-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
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C30H33Cl2N3O4S
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1
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| 1 |
IC50 = 12 nM
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CP0509687
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[2-benzyl-4-(naphthalen-1-ylmethylamino)piperidin-1-yl]-(3,5-dimethylphenyl)methanone
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C32H34N2O
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1
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| 1 |
IC50 = 12 nM
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CP0457106
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1-[2-[[3-fluoro-5-(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazine
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C20H22F4N2O
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2
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| 1 |
IC50 = 12.59 nM
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| 2 |
Ki = 12.59 nM
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CP0504242
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1-[(1R)-2-[(3,5-dibromophenyl)methoxy]-1-phenylethyl]piperazine
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C19H22Br2N2O
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1
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| 1 |
IC50 = 12.59 nM
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CP0496512
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(3,5-Bis-trifluoromethyl-benzyl)-(4-phenyl-piperidin-4-ylmethyl)-amine
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C21H22F6N2
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1
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| 1 |
IC50 = 12.6 nM
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CP0430478
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3-[(3,5-dimethylphenyl)methoxy]-N-ethyl-1,1-diphenylpropan-2-amine
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C26H31NO
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1
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| 1 |
IC50 = 12.7 nM
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CP0534921
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2-benzylamino-3-(3,4-dichlorobenzylsulfanyl)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2R)-propan-1-one
Show/Hide
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C30H33Cl2N3O3S2
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1
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| 1 |
IC50 = 13 nM
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CP0491330
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(S)-2-Benzylamino-3-(3,4-dichloro-benzyloxy)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C28H31Cl2N3O3
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1
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| 1 |
IC50 = 13 nM
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CP0241400
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(S)-2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamine
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C17H15F6NO
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1
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| 1 |
IC50 = 13 nM
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CP0488129
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(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-methyl-N-[(1-methyltetrazol-5-yl)methyl]-1-phenylethanamine
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C21H21F6N5O
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1
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| 1 |
IC50 = 13 nM
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CP0565808
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3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-isopropyl-piperazin-1-yl)-propan-1-one
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C25H29Cl2N3O
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1
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| 1 |
IC50 = 13 nM
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CP0401116
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(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-methoxy-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
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C21H24FNO3
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1
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| 1 |
IC50 = 13 nM
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CP0553861
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(piperidine-1-carbonyl)pyrrolidine-3-carboxamide
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C27H29F6N3O2
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1
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| 1 |
IC50 = 13 nM
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CP0540335
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(2S,4S)-Piperidine-1,2,4-tricarboxylic acid 2-{[2-(carbamoylmethyl-amino)-ethyl]-amide} 4-dipentylamide 1-diphenylamide
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C34H50N6O4
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1
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| 1 |
IC50 = 13 nM
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CP0506849
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1-(3,5-Dibromo-benzyloxymethyl)-2,2-diphenyl-ethylamine
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C22H21Br2NO
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1
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| 1 |
IC50 = 13.3 nM
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CP0402518
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2-(3,5-Bis-trifluoromethyl-benzyloxy)-1-phenyl-ethylamine
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C17H15F6NO
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1
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| 1 |
IC50 = 13.5 nM
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CP0454859
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(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-methyl-2-phenyl-piperidine
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C21H21F6NO
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1
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| 1 |
IC50 = 14 nM
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CP0430267
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1'N-[1-benzyl(methyl)carbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]-1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
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C33H37N5O2S
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1
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| 1 |
IC50 = 14 nM
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CP0501016
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3-[5,7-Dichloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C28H26Cl3N3O2
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1
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| 1 |
IC50 = 14 nM
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CP0542512
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(2R)-3-[(3,5-dimethylphenyl)methoxy]-N,N-dimethyl-1,1-diphenylpropan-2-amine
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C26H31NO
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1
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| 1 |
IC50 = 14 nM
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CP0492312
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N-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-N-methyl-2,2-diphenylacetamide
Show/Hide
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C25H21F6NO
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1
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| 1 |
IC50 = 14 nM
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CP0496890
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(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-[(2-methyltetrazol-5-yl)methyl]-1-phenylethanamine
Show/Hide
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C20H19F6N5O
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1
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| 1 |
IC50 = 15 nM
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CP0438563
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(5-Chloro-2-(4-chloro-phenyl)-3-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-3-oxo-propyl}-indol-1-yl)-acetic acid methyl ester
Show/Hide
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C31H31Cl2N3O4
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1
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| 1 |
IC50 = 15 nM
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CP0437566
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(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-methyl-N-[(2-methyltetrazol-5-yl)methyl]-1-phenylethanamine
Show/Hide
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C21H21F6N5O
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1
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| 1 |
IC50 = 16 nM
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CP0397229
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(3S,5S,10S)-10-(2,5-Dimethoxy-phenyl)-5-(4-fluoro-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
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C22H26FNO4
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1
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| 1 |
IC50 = 16 nM
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CP0485853
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(+/-)-trans-1-(3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)-1,3,3-trimethylurea
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C24H26F6N2O2
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1
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| 1 |
IC50 = 16 nM
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CP0529867
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(S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-methyl-amide)
Show/Hide
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C41H58N6O4
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1
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| 1 |
IC50 = 17 nM
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CP0501246
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3-(3,5-Bis-trifluoromethyl-benzyloxy)-1,1-diphenyl-propan-2-ol
Show/Hide
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C24H20F6O2
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1
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| 1 |
IC50 = 17 nM
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CP0523852
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N-[2-[1-[(2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]propanoyl]piperidin-4-yl]phenyl]methanesulfonamide
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C29H33Cl2N3O4S
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1
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| 1 |
IC50 = 17 nM
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CP0461093
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3-(3,5-Dimethyl-benzyloxy)-1,1-diphenyl-propan-2-ol
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C24H26O2
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1
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| 1 |
IC50 = 17 nM
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CP0559852
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3-benzyloxy-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
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C30H33Cl2N3O4S
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1
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| 1 |
IC50 = 18 nM
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CP0463535
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5-(5,9-Diphenyl-1,7-dioxa-4-aza-spiro[5.5]undec-4-ylmethyl)-2,4-dihydro-[1,2,4]triazol-3-one
Show/Hide
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C23H26N4O3
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1
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| 1 |
IC50 = 19 nM
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CP0431661
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2-Methyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
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C27H20F6N2O
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1
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| 1 |
IC50 = 19 nM
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CP0465359
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2-Benzhydryl-3-(3-methyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C28H31NO
|
1
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| 1 |
IC50 = 20 nM
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CP0535828
|
(2S,4S)-1-[(3-Chloro-phenyl)-phenyl-carbamoyl]-4-dipentylcarbamoyl-piperidine-2-carboxylic acid
Show/Hide
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C30H40ClN3O4
|
1
|
| 1 |
IC50 = 20 nM
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CP0409086
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N-[3-[(3,5-dimethylphenyl)methoxy]-1,1-diphenylpropan-2-yl]acetamide
Show/Hide
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C26H29NO2
|
1
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| 1 |
IC50 = 21 nM
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CP0522741
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-fluorophenyl)-N-methyltetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
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C26H16F7N5O
|
1
|
| 1 |
IC50 = 21 nM
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CP0299596
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(S)-2-Benzoylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
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C27H26N2O3
|
1
|
| 1 |
IC50 = 22 nM
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CP0448996
|
2-(3,5-Bis-trifluoromethyl-phenyl)-N-(4-dimethylamino-1-phenyl-cyclohexyl)-propionamide
Show/Hide
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C25H28F6N2O
|
1
|
| 1 |
IC50 = 22 nM
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CP0501731
|
3-(4-chlorobenzyloxy)-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
|
C30H32Cl3N3O4S
|
1
|
| 1 |
IC50 = 23 nM
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CP0524185
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benzyl (2S)-3-(1H-indol-3-yl)-2-[(1-methylsulfanylspiro[2H-indole-3,4'-piperidine]-1'-carbonyl)amino]propanoate
Show/Hide
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C32H34N4O3S
|
1
|
| 1 |
IC50 = 23 nM
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CP0506567
|
(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenyl-N-(2H-tetrazol-5-ylmethyl)ethanamine
Show/Hide
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C19H17F6N5O
|
1
|
| 1 |
IC50 = 23 nM
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CP0384895
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2-benzylamino-3-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
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C30H34Cl2N4O3S
|
1
|
| 1 |
IC50 = 24 nM
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CP0458655
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(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(2-trifluoromethyl-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
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C21H21F4NO2
|
1
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| 1 |
IC50 = 24 nM
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CP0505459
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(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methyl-4-phenyl-1-(pyrimidine-5-carbonyl)pyrrolidine-3-carboxamide
Show/Hide
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C26H22F6N4O2
|
1
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| 1 |
IC50 = 24 nM
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CP0498589
|
2-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-2-oxo-acetamide
Show/Hide
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C22H20F6N2O3
|
1
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| 1 |
IC50 = 25 nM
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CP0438293
|
1-[2-[(3,5-dimethylphenyl)methoxy]-1-phenylethyl]piperazine
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C21H28N2O
|
2
|
| 1 |
IC50 = 25.12 nM
|
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| 2 |
Ki = 25.12 nM
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CP0467335
|
1-[(1R)-2-[(3,5-dichlorophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
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C19H22Cl2N2O
|
1
|
| 1 |
IC50 = 25.12 nM
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CP0334643
|
N-(3,4-dichlorophenyl)-2-(3,5-dimethylphenoxy)-N-piperidin-4-ylacetamide
Show/Hide
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C21H24Cl2N2O2
|
1
|
| 1 |
IC50 = 25.12 nM
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CP0384946
|
3-[3,5-bis(trifluoromethyl)phenyl]-N-[(3-methylphenyl)methyl]-N-piperidin-4-ylpropanamide
Show/Hide
|
C24H26F6N2O
|
1
|
| 1 |
IC50 = 25.12 nM
|
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CP0529875
|
2-[3,5-bis(trifluoromethyl)phenoxy]-N-[(3-chlorophenyl)methyl]-N-piperidin-4-ylacetamide
Show/Hide
|
C22H21ClF6N2O2
|
1
|
| 1 |
IC50 = 25.12 nM
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CP0489418
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-phenyltetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
|
C26H17F6N5O
|
1
|
| 1 |
IC50 = 26 nM
|
|
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CP0449393
|
3-benzyloxy-2-(3-chlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H34ClN3O4S
|
1
|
| 1 |
IC50 = 27 nM
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CP0476669
|
2-(4-{3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-propionyl}-piperazin-1-yl)-N-phenyl-acetamide
Show/Hide
|
C30H30Cl2N4O2
|
1
|
| 1 |
IC50 = 30 nM
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CP0507715
|
(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(3-trifluoromethyl-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
|
C21H21F4NO2
|
1
|
| 1 |
IC50 = 30 nM
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|
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CP0530199
|
5-Allyl-3-(3,5-bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
Show/Hide
|
C24H18F6N2O3
|
1
|
| 1 |
IC50 = 31 nM
|
|
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CP0424587
|
3-[2-(4-Chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C28H28ClN3O2
|
1
|
| 1 |
IC50 = 31 nM
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CP0398462
|
2-[3,5-bis(trifluoromethyl)phenoxy]-N-(3,4-dichlorophenyl)-N-piperidin-4-ylacetamide
Show/Hide
|
C21H18Cl2F6N2O2
|
1
|
| 1 |
IC50 = 31.62 nM
|
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CP0454352
|
3-[3,5-bis(trifluoromethyl)phenyl]-N-[(4-fluorophenyl)methyl]-N-piperidin-4-ylpropanamide
Show/Hide
|
C23H23F7N2O
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
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CP0528910
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,2-dimethyl-1-oxido-4-phenylpyridin-1-ium-3-carboxamide
Show/Hide
|
C23H18F6N2O2
|
1
|
| 1 |
IC50 = 32 nM
|
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CP0463680
|
2-Benzhydryl-3-(3,5-difluoro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H27F2NO
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
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CP0505514
|
3-benzyloxy-2-(4-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C32H40N4O4S
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
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CP0448815
|
(2S,4S)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-piperidine-2-carboxylic acid
Show/Hide
|
C30H41N3O4
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
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CP0409869
|
1-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-cyclohexylmethyl]-3-pyridin-3-ylmethyl-urea
Show/Hide
|
C29H29F6N3O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
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CP0509783
|
3-(2-chlorobenzyloxy)-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
|
C30H32Cl3N3O4S
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
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CP0504754
|
1-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-yl]-ethanone
Show/Hide
|
C22H21F6NO2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
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CP0555053
|
2-Benzhydryl-3-(2,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C29H33NO
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
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CP0151361
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-1-furan-2-ylmethyl-2-phenyl-piperidine
Show/Hide
|
C25H23F6NO2
|
1
|
| 1 |
IC50 = 36 nM
|
|
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CP0538269
|
2-benzylamino-3-(2-chlorobenzyloxy)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
|
C30H34ClN3O4S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
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CP0529161
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-phenylpyrrolo[1,2-a]quinoline-4-carboxamide
Show/Hide
|
C29H20F6N2O
|
1
|
| 1 |
IC50 = 36 nM
|
|
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CP0463779
|
2-Benzhydryl-3-(2-bromo-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28BrNO
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
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CP0529337
|
2-Benzhydryl-3-(3-fluoro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28FNO
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
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CP0403811
|
4-(3-Iodo-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C19H22INO
|
1
|
| 1 |
IC50 = 38 nM
|
|
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CP0387566
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-phenylimidazo[1,2-a]quinoline-4-carboxamide
Show/Hide
|
C28H19F6N3O
|
1
|
| 1 |
IC50 = 38 nM
|
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CP0448198
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3-propan-2-ylphenyl)ethyl]piperazine
Show/Hide
|
C24H28F6N2O
|
1
|
| 1 |
IC50 = 39.81 nM
|
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|
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CP0562085
|
(+/-)-trans-benzyl-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylcarbamate
Show/Hide
|
C28H25F6NO3
|
1
|
| 1 |
IC50 = 40 nM
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|
|
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CP0395530
|
(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(3-diethylamino-propyl)-amide] 4-dipentylamide 1-diphenylamide
Show/Hide
|
C36H56N6O3
|
1
|
| 1 |
IC50 = 41 nM
|
|
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CP0428453
|
1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[2-(4-chloro-phenyl)-1-methyl-1H-pyrrolo[3,2-c]pyridin-3-yl]-propan-1-one
Show/Hide
|
C29H30ClN3O2
|
1
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| 1 |
IC50 = 41 nM
|
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CP0555202
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,2,6-trimethyl-4-phenylpyridine-3-carboxamide
Show/Hide
|
C24H20F6N2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
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CP0449429
|
3-benzyloxy-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2R)-propan-1-one
Show/Hide
|
C30H33Cl2N3O4S
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
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CP0523381
|
11-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-oxo-propyl}-2-methyl-isoindolo[2,1-a]indol-6-one
Show/Hide
|
C30H29N3O3
|
1
|
| 1 |
IC50 = 42 nM
|
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|
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CP0464802
|
2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
|
C27H20F6N2O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
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CP0101869
|
(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-1-(1H-tetrazol-5-ylmethyl)-piperidine
Show/Hide
|
C22H21F6N5O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
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CP0427325
|
1'-[3-benzyloxy-2-(3,4-dichlorophenylcarboxamido)propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
|
C31H33Cl2N3O5S
|
1
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| 1 |
IC50 = 43 nM
|
|
|
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CP0898983
|
6-N1N-(1-formylethyl)-2-aminoacetamide9-(4-aminobutyl)-15,18,30-tribenzyl-12-carbamoylmethyl-27,33-di(1-hydroxyethyl)-36-hydroxymethyl-7,10,13,16,19,22,25,28,31,34,37-undecaoxo-3,4-dithia-8,11,14,17,20,23,26,29,32,35,38-undecaazacyclooctatriacontane-1-carboxylic acid21-L-2-amino-3-(1H-3-indolyl)propanal24-4-fluoro-1-methylbenzene
Show/Hide
|
C79H100FN17O19S2
|
3
|
| 1 |
IC50 = 44 nM
|
|
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| 2 |
IC50 = 1400 nM
|
|
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| 3 |
IC50 = 3600 nM
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CP0515782
|
2-[[(1S,2R,3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclopentyl]amino]acetamide
Show/Hide
|
C22H22F6N2O2
|
1
|
| 1 |
IC50 = 45 nM
|
|
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CP0515964
|
N-[(3,5-dichlorophenyl)methyl]-N-methyl-3,3-diphenylpropanamide
Show/Hide
|
C23H21Cl2NO
|
1
|
| 1 |
IC50 = 45 nM
|
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CP0457322
|
N-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2,2-diphenylacetamide
Show/Hide
|
C24H19F6NO
|
1
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| 1 |
IC50 = 46 nM
|
|
|
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CP0547380
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-2,2-diphenylacetamide
Show/Hide
|
C24H19F6NO
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
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CP0506813
|
3-(2-Methoxy-phenyl)-6-phenyl-1-oxa-7-aza-spiro[4.5]dec-3-ene
Show/Hide
|
C21H23NO2
|
1
|
| 1 |
IC50 = 49 nM
|
|
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CP0440733
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-methoxyphenyl)ethyl]piperazine
Show/Hide
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C22H24F6N2O2
|
2
|
| 1 |
IC50 = 50.12 nM
|
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| 2 |
Ki = 50.12 nM
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CP0516636
|
N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-N-(4-fluorophenyl)piperidin-4-amine
Show/Hide
|
C22H23F7N2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
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CP0508278
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(chloromethyl)-N-methyl-4-phenylpyridine-3-carboxamide
Show/Hide
|
C23H17ClF6N2O
|
1
|
| 1 |
IC50 = 52 nM
|
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CP0241621
|
(2S,3S)-2-Benzhydryl-3-(3-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C28H28F3NO
|
2
|
| 1 |
IC50 = 53 nM
|
|
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| 2 |
IC50 = 2100 nM
|
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CP0503242
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-methyl-6-(4-methylpiperazin-1-yl)-4-phenylpyridine-3-carboxamide
Show/Hide
|
C27H26F6N4O
|
1
|
| 1 |
IC50 = 53 nM
|
|
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CP0507683
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,5-dimethyl-7-phenyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
Show/Hide
|
C24H18F6N4O
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
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CP0506570
|
2-benzylamino-3-[3,4-dichlorobenzyl(methyl)amino]-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C31H36Cl2N4O3S
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
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CP0520191
|
(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dimethylamino-ethyl)-amide] 4-dipentylamide 1-diphenylamide
Show/Hide
|
C33H50N6O3
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0218761
|
(S)-2-(3,5-Dimethyl-benzyloxy)-1-phenyl-ethylamine
Show/Hide
|
C17H21NO
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0406275
|
3-benzyloxy-2-(3-methylbenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C31H37N3O4S
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0397992
|
4-(3-tert-Butyl-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C23H31NO
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0454858
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-methyl-1H-indol-3-yl]-1-(4-hydroxymethyl-4-phenyl-piperidin-1-yl)-propan-1-one
Show/Hide
|
C30H30Cl2N2O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0527715
|
3-[(3,5-dimethylphenyl)methoxy]-1,1-diphenyl-N-propan-2-ylpropan-2-amine
Show/Hide
|
C27H33NO
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0457347
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-(4-methylphenyl)tetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
|
C27H19F6N5O
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0502477
|
2-Benzhydryl-3-(3-methoxy-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C28H31NO2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
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CP0507724
|
1'N-[1-benzyl(methyl)carbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
|
C33H36N4O2
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
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CP0488158
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3,3-diphenylpropanamide
Show/Hide
|
C25H21F6NO
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
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CP0535363
|
(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-amino-ethyl)-amide] 4-dipentylamide 1-diphenylamide
Show/Hide
|
C31H46N6O3
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
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CP0472244
|
3-benzyloxy-2-(4-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C31H37N3O5S
|
1
|
| 1 |
IC50 = 57 nM
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CP0195525
|
4-Phenyl-4-(3-trifluoromethyl-benzyloxymethyl)-piperidine
Show/Hide
|
C20H22F3NO
|
1
|
| 1 |
IC50 = 57 nM
|
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CP0531179
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,5-dimethyl-7-phenyltetrazolo[1,5-a]pyridine-6-carboxamide
Show/Hide
|
C23H17F6N5O
|
1
|
| 1 |
IC50 = 57 nM
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CP0535804
|
3-benzyloxy-2-(3-chlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H34ClN3O4S
|
1
|
| 1 |
IC50 = 58 nM
|
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CP0511997
|
3-benzyloxy-2-(3-bromobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H34BrN3O4S
|
1
|
| 1 |
IC50 = 60 nM
|
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CP0372389
|
N-[2-[1-[(2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]propanoyl]piperidin-4-yl]phenyl]-N-methylmethanesulfonamide
Show/Hide
|
C30H35Cl2N3O4S
|
1
|
| 1 |
IC50 = 61 nM
|
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CP0391471
|
2-Benzhydryl-3-(3-chloro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28ClNO
|
1
|
| 1 |
IC50 = 62 nM
|
|
|
|
CP0438610
|
2-Benzhydryl-3-(3-phenoxy-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C33H33NO2
|
1
|
| 1 |
IC50 = 62 nM
|
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|
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CP0434216
|
(3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(cyclohexylmethyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide
Show/Hide
|
C28H32F6N2O
|
1
|
| 1 |
IC50 = 62 nM
|
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CP0945080
|
3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-2,4-dioxo-imidazolidine-1-carboxylic acid methylamide
Show/Hide
|
C23H18F6N4O3
|
1
|
| 1 |
IC50 = 63 nM
|
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CP0415334
|
2-benzylamino-3-(3,4-dichlorobenzylsulfonyl)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2R)-propan-1-one
Show/Hide
|
C30H33Cl2N3O5S2
|
1
|
| 1 |
IC50 = 63 nM
|
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CP0496516
|
4-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-4-phenyl-piperidine
Show/Hide
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C22H23F6N
|
1
|
| 1 |
IC50 = 63 nM
|
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CP0429974
|
2-[(2S,3S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-3-phenylmorpholin-4-yl]acetic acid
Show/Hide
|
C21H19F6NO4
|
1
|
| 1 |
IC50 = 66 nM
|
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CP0077212
|
(S)-2-Acetylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
|
C22H24N2O3
|
1
|
| 1 |
IC50 = 67 nM
|
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CP0508683
|
2-Benzhydryl-3-(2-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C28H28F3NO
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
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CP0496804
|
2-Acetylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
|
C22H24N2O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0456459
|
(+/-)-trans-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentanecarboxylic acid
Show/Hide
|
C21H18F6O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
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CP0495475
|
methyl 2-[(2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidin-1-yl]-2-oxoacetate
Show/Hide
|
C23H21F6NO4
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0520159
|
1'N-[1-benzyl(methyl)carbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]spiro[1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
|
C33H34N4O2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0403912
|
(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-N-methyl-1-phenyl-N-(2H-tetrazol-5-ylmethyl)ethanamine
Show/Hide
|
C20H19F6N5O
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
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CP0502349
|
3-benzyloxy-2-(3-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C31H37N3O5S
|
1
|
| 1 |
IC50 = 71 nM
|
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|
CP0449199
|
(2S,4R)-Piperidine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-({2-[(2-methoxy-benzyl)-methyl-amino]-ethyl}-amide)
Show/Hide
|
C41H57N5O4
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0526089
|
1-(3-Chloro-benzyloxymethyl)-2,2-diphenyl-ethylamine
Show/Hide
|
C22H22ClNO
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0528883
|
4-Acetylamino-4-phenyl-piperidine-1-carboxylic acid [(S)-1-(benzyl-methyl-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
Show/Hide
|
C33H37N5O3
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0510104
|
1-(3-Iodo-benzyloxymethyl)-2,2-diphenyl-ethylamine
Show/Hide
|
C22H22INO
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
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CP0501746
|
3-benzyloxy-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
|
C30H33Cl2N3O4S
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0504131
|
2-[3,5-bis(trifluoromethyl)phenoxy]-N-[(3-methylphenyl)methyl]-N-piperidin-4-ylacetamide
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0524125
|
1-(5H-Dibenzo[a,d]cyclohepten-5-yl)-2-(3,5-dimethyl-benzyloxy)-ethylamine
Show/Hide
|
C26H27NO
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0477035
|
2-Benzhydryl-3-(2-chloro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28ClNO
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0448257
|
2-benzylamino-3-benzyloxy-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H35N3O4S
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0496973
|
3-[2-(2-Methoxy-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C30H33N3O3
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0410782
|
Benzyl-[1-(3,5-dimethyl-benzyloxymethyl)-2,2-diphenyl-ethyl]-amine
Show/Hide
|
C31H33NO
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0460894
|
4-Phenyl-4-(2-trifluoromethyl-benzyloxymethyl)-piperidine
Show/Hide
|
C20H22F3NO
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
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CP0531973
|
2-[(2S,3S)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylpiperidin-1-yl]acetic acid
Show/Hide
|
C22H21F6NO3
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0463622
|
2-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymethyl)-benzonitrile
Show/Hide
|
C28H28N2O
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0495470
|
3-(5-Fluoro-2-phenyl-1H-indol-3-yl)-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C28H28FN3O2
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
|
CP0505555
|
1'-[3-benzyloxy-2-(3,4-dichlorophenylsulfonamido)propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
|
C29H31Cl2N3O6S2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0465329
|
3-[2-(2-Bromo-phenyl)-5-methyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C29H30BrN3O2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0530254
|
4-(3,5-Dimethoxy-benzyloxymethyl)-4-phenyl-piperidine
Show/Hide
|
C21H27NO3
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0482262
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-6-chloro-N,2-dimethyl-4-phenylpyridine-3-carboxamide
Show/Hide
|
C23H17ClF6N2O
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
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CP0381056
|
4-Phenyl-quinoline-3-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
|
C26H18F6N2O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
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CP0496396
|
1-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-2-(3,5-dimethyl-benzyloxy)-ethylamine
Show/Hide
|
C26H29NO
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0478217
|
2-Benzhydryl-3-(2-fluoro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28FNO
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
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CP0491679
|
N-(cyclopropylmethyl)-3-[(3,5-dimethylphenyl)methoxy]-1,1-diphenylpropan-2-amine
Show/Hide
|
C28H33NO
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
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CP0453351
|
3-[1-Benzyl-5-chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C35H33Cl2N3O2
|
1
|
| 1 |
IC50 = 96 nM
|
|
|
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CP0513242
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N,2-dimethyl-4-phenylpyridine-3-carboxamide
Show/Hide
|
C23H18F6N2O
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
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CP0525399
|
(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-phenyl-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
|
C20H22FNO2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
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CP0434537
|
3-benzyloxy-2-(2,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H33Cl2N3O4S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
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CP0453949
|
1-[2-[(3,5-ditert-butylphenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
|
C27H40N2O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
Ki = 100 nM
|
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CP0463874
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(4-fluorophenyl)ethyl]piperazine
Show/Hide
|
C21H21F7N2O
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
Ki = 79.43 nM
|
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|
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CP0469368
|
2-(3,5-dichlorophenoxy)-N-(3,4-dichlorophenyl)-N-piperidin-4-ylacetamide
Show/Hide
|
C19H18Cl4N2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
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CP0498429
|
3-[3,5-bis(trifluoromethyl)phenyl]-N-[(2-chlorophenyl)methyl]-N-piperidin-4-ylpropanamide
Show/Hide
|
C23H23ClF6N2O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0511977
|
N-[(3-chlorophenyl)methyl]-2-(3,5-dimethylphenoxy)-N-piperidin-4-ylacetamide
Show/Hide
|
C22H27ClN2O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0407221
|
(1S,2R,3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclopentan-1-amine
Show/Hide
|
C20H19F6NO
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0528751
|
2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C23H23F6NO
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
|
CP0100035
|
(S)-3-(1H-Indol-3-yl)-2-(3-methyl-ureido)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
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CP0555118
|
3-[5-Chloro-2-(4-chloro-phenyl)-1-cyclopropylmethyl-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
|
C32H33Cl2N3O2
|
1
|
| 1 |
IC50 = 103 nM
|
|
|
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CP0509405
|
2-Benzhydryl-3-(2,5-difluoro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H27F2NO
|
1
|
| 1 |
IC50 = 106 nM
|
|
|
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CP0532412
|
2-Benzyl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C23H29NO
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
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CP0532401
|
2-Benzhydryl-3-benzyloxy-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H29NO
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
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CP0453412
|
(2S,3S)-1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidine
Show/Hide
|
C27H25F6NO
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
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CP0455457
|
N-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-3,3-diphenylpropanamide
Show/Hide
|
C25H21F6NO
|
1
|
| 1 |
IC50 = 112 nM
|
|
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CP0380795
|
2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl-ethyl)-N-methyl-acetamide
Show/Hide
|
C25H21F6NO
|
1
|
| 1 |
IC50 = 114 nM
|
|
|
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CP0309924
|
2-Benzylidene-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C23H27NO
|
2
|
| 1 |
IC50 = 120 nM
|
|
|
| 2 |
IC50 = 129 nM
|
|
|
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CP0457310
|
3-benzyloxy-2-(4-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
|
C30H34N4O6S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0448659
|
N-[3,5-bis(trifluoromethyl)phenyl]-N-methyl-3,3-diphenylpropanamide
Show/Hide
|
C24H19F6NO
|
1
|
| 1 |
IC50 = 121 nM
|
|
|
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CP0197252
|
[(2S)-1-[(3,5-dimethylphenyl)methoxy]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-trimethylazanium
Show/Hide
|
C23H29N2O2+
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
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CP0048980
|
(2S,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C29H27F6NO
|
1
|
| 1 |
IC50 = 125 nM
|
|
|
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CP0442611
|
N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-N-[(4-fluorophenyl)methyl]piperidin-4-amine
Show/Hide
|
C23H25F7N2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
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CP0506562
|
N-[(3-chlorophenyl)methyl]-2-(3,5-dichlorophenoxy)-N-piperidin-4-ylacetamide
Show/Hide
|
C20H21Cl3N2O2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0538452
|
2-[3,5-bis(trifluoromethyl)phenoxy]-N-[(2-chlorophenyl)methyl]-N-piperidin-4-ylacetamide
Show/Hide
|
C22H21ClF6N2O2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0528869
|
3-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymethyl)-benzonitrile
Show/Hide
|
C28H28N2O
|
1
|
| 1 |
IC50 = 127 nM
|
|
|
|
CP0470758
|
(S)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-piperazine-2-carboxylic acid
Show/Hide
|
C29H40N4O4
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0285940
|
(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
|
C25H30N2O4
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0562316
|
(3S,10S)-3,10-diphenyl-1-oxa-9-azaspiro[4.5]decane
Show/Hide
|
C20H23NO
|
1
|
| 1 |
IC50 = 133 nM
|
|
|
|
CP0475779
|
(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-acetylamino-ethyl)-amide] 4-dipentylamide 1-diphenylamide
Show/Hide
|
C33H48N6O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0467836
|
(3R,4S)-tert-butyl 3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl)-4-phenylpyrrolidine-1-carboxylate
Show/Hide
|
C25H26F6N2O3
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0384626
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenylimidazo[1,5-a]quinoline-4-carboxamide
Show/Hide
|
C27H17F6N3O
|
1
|
| 1 |
IC50 = 146 nM
|
|
|
|
CP0502675
|
2-Benzhydryl-3-(2-methyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C28H31NO
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0498211
|
1-(2,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethylamine
Show/Hide
|
C24H27NO
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0463714
|
3-{1-benzyloxymethyl-2-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-2-oxoethylaminomethyl}benzonitrile
Show/Hide
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C31H34N4O4S
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1
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| 1 |
IC50 = 152 nM
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CP0894954
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3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-1-methyl-imidazolidine-2,4-dione
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C22H17F6N3O2
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1
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| 1 |
IC50 = 153 nM
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CP0504132
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3-benzyloxy-2-(2,3-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
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C30H33Cl2N3O4S
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1
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| 1 |
IC50 = 153 nM
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CP0406293
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3-benzyloxy-2-(3,4-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2S)-propan-1-one
Show/Hide
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C30H34FN3O4S
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1
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| 1 |
IC50 = 157 nM
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CP0455133
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3-benzyloxy-2-(2-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
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C31H37N3O5S
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1
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| 1 |
IC50 = 163 nM
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CP0436604
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N-[(2R)-1-[benzyl(methyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-1-methylsulfanylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide
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C33H37N5O2S
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1
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| 1 |
IC50 = 164 nM
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CP0464600
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2N-benzyl-1-(3,4-dichlorobenzyloxy)-3-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-(2R)-propan-2-amine
Show/Hide
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C30H35Cl2N3O3S
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1
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| 1 |
IC50 = 170 nM
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CP0509176
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4-Phenyl-4-(3-trifluoromethoxy-benzyloxymethyl)-piperidine
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C20H22F3NO2
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1
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| 1 |
IC50 = 170 nM
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CP0420832
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5,9-Diphenyl-1,7-dioxa-4-aza-spiro[5.5]undecane
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C20H23NO2
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1
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| 1 |
IC50 = 170 nM
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CP0463782
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2-Benzhydryl-3-(3,4-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C29H33NO
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1
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| 1 |
IC50 = 172 nM
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CP0505117
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(3S,5S,10S)-5-(4-Fluoro-phenyl)-10-(3-methoxy-phenyl)-1,8-dioxa-4-aza-spiro[5.5]undecane
Show/Hide
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C21H24FNO3
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1
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| 1 |
IC50 = 183 nM
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CP0288615
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2-Benzyl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C23H23F6NO
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1
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| 1 |
IC50 = 197 nM
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CP0469894
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2-Benzhydryl-3-(3-nitro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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C27H28N2O3
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1
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| 1 |
IC50 = 197 nM
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CP0455445
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1-[2-[(3,5-difluorophenyl)methoxy]-1-phenylethyl]piperazine
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C19H22F2N2O
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2
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| 1 |
IC50 = 199.53 nM
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| 2 |
Ki = 199.53 nM
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CP0225569
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3-[3,5-bis(trifluoromethyl)phenyl]-N-(4-fluorophenyl)-N-piperidin-4-ylpropanamide
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C22H21F7N2O
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1
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| 1 |
IC50 = 199.53 nM
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CP0539582
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2-[3,5-bis(trifluoromethyl)phenoxy]-N-(3-chlorophenyl)-N-piperidin-4-ylacetamide
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C21H19ClF6N2O2
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1
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| 1 |
IC50 = 199.53 nM
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CP0523277
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,5-dimethyl-benzyl)-methyl-amino]-ethyl}-methyl-amide) 4-dipentylamide 1-diphenylamide
Show/Hide
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C42H60N6O3
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1
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| 1 |
IC50 = 200 nM
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CP0445900
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2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-1-phenyl-8-aza-bicyclo[3.2.1]octane
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C23H23F6NO
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1
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| 1 |
IC50 = 200 nM
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CP0449167
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1-(3,5-Bis-trifluoromethyl-benzyl)-3-(1H-indol-3-ylmethyl)-pyrrolidine-2,5-dione
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C22H16F6N2O2
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1
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| 1 |
IC50 = 203 nM
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CP0392838
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4-Phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
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C25H16F6N2O
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1
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| 1 |
IC50 = 208 nM
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CP0521936
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-diisopropylamino-ethyl)-amide] 4-dipentylamide 1-diphenylamide
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C37H58N6O3
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1
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| 1 |
IC50 = 217 nM
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CP0941581
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3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-2,4-dioxo-imidazolidine-1-carboxylic acid phenylamide
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C28H20F6N4O3
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1
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| 1 |
IC50 = 220 nM
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CP0373262
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(4S,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-37-[[(2S)-2-[(2-aminoacetyl)amino]propanoyl]amino]-34-(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-19-[(4-fluorophenyl)methyl]-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
Show/Hide
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C79H100FN17O19S2
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2
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| 1 |
IC50 = 220 nM
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| 2 |
IC50 = 240 nM
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CP0391389
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N-[(3,5-dimethoxyphenyl)methyl]-N-methyl-3,3-diphenylpropanamide
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C25H27NO3
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1
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| 1 |
IC50 = 226 nM
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CP0498826
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N-[(3,5-dichlorophenyl)methyl]-3,3-diphenylpropanamide
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C22H19Cl2NO
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1
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| 1 |
IC50 = 226 nM
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CP0425823
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2-[(2S,3S)-3-(2-Methoxy-benzylamino)-2-phenyl-piperidin-1-yl]-acetamide
Show/Hide
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C21H27N3O2
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1
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| 1 |
IC50 = 227 nM
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CP0530631
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1'N-[1-benzylcarbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
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C32H34N4O2
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1
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| 1 |
IC50 = 227 nM
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CP0373476
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2-Hydroxymethyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
Show/Hide
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C26H18F6N2O2
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1
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| 1 |
IC50 = 227 nM
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CP0534926
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3,3-diphenylpropanamide
Show/Hide
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C24H19F6NO
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1
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| 1 |
IC50 = 235 nM
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CP0522743
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-fluorophenyl)tetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
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C25H14F7N5O
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1
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| 1 |
IC50 = 235 nM
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CP0531178
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(chloromethyl)-4-phenylpyridine-3-carboxamide
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C22H15ClF6N2O
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1
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| 1 |
IC50 = 235 nM
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CP0463662
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1'N-[1-benzyl(ethyl)carbamoyl-2-(1H-3-indolyl)-(1S)-ethyl]spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
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C34H38N4O2
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1
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| 1 |
IC50 = 242 nM
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CP0401562
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1-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-piperazin-2-one
Show/Hide
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C22H19F6N3O
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1
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| 1 |
IC50 = 243 nM
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CP0532411
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2-Benzhydryl-3-(4-methyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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C28H31NO
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1
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| 1 |
IC50 = 246 nM
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CP0380180
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(4S,7S,10S,13S,16S,19S,22R,25S,28S,31S,34S,37R)-37-amino-34-(4-aminobutyl)-31-(2-amino-2-oxoethyl)-13,25,28-tribenzyl-19-[(4-fluorophenyl)methyl]-10,16-bis[(1R)-1-hydroxyethyl]-7-(hydroxymethyl)-22-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecazacyclooctatriacontane-4-carboxylic acid
Show/Hide
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C74H92FN15O17S2
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2
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| 1 |
IC50 = 250 nM
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| 2 |
IC50 = 260 nM
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CP0490068
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N-(3-chlorophenyl)-2-[(4-phenyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]acetamide
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C21H16ClN5OS
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1
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| 1 |
IC50 = 250 nM
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CP0448026
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(2S,4S)-1-Diphenylcarbamoyl-2-{2-[(2-methoxy-benzyl)-methyl-amino]-ethylcarbamoyl}-piperidine-4-carboxylic acid methyl ester
Show/Hide
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C32H38N4O5
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1
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| 1 |
IC50 = 250 nM
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CP0548420
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2-Benzhydryl-3-(4-fluoro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C27H28FNO
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1
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| 1 |
IC50 = 252 nM
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CP0418810
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2-Methyl-4-phenyl-quinoline-3-carboxylic acid 3,5-bis-trifluoromethyl-benzylamide
Show/Hide
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C26H18F6N2O
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1
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| 1 |
IC50 = 257 nM
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CP0547398
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1'-[3-benzyloxy-2-(3,4-dichlorophenylcarboxamido)propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
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C30H31Cl2N3O5S
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1
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| 1 |
IC50 = 260 nM
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CP0408374
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(5S)-5-[[[(1S,2R,3R)-3-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-2-phenylcyclopentyl]amino]methyl]pyrrolidin-2-one
Show/Hide
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C25H26F6N2O2
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1
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| 1 |
IC50 = 260 nM
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CP0449309
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(S)-2-Benzylamino-3-(3,4-dichloro-benzyloxy)-1-[4-(2-methoxy-phenyl)-piperidin-1-yl]-propan-1-one
Show/Hide
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C29H32Cl2N2O3
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1
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| 1 |
IC50 = 263 nM
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CP0455699
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(S)-Piperazine-1,2,4-tricarboxylic acid 4-dipentylamide 1-diphenylamide 2-[(2-methoxy-ethyl)-amide]
Show/Hide
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C32H47N5O4
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1
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| 1 |
IC50 = 267 nM
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CP0448430
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1-(3,5-Bis-trifluoromethyl-benzyl)-4-(1H-indol-3-ylmethyl)-imidazolidin-2-one
Show/Hide
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C21H17F6N3O
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1
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| 1 |
IC50 = 267 nM
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CP0513241
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-6-chloro-2-methyl-4-phenylpyridine-3-carboxamide
Show/Hide
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C22H15ClF6N2O
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1
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| 1 |
IC50 = 270 nM
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CP0944910
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3-(3,5-Dichloro-benzyl)-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
Show/Hide
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C19H14Cl2N2O3
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1
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| 1 |
IC50 = 273 nM
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CP0513243
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-methyl-7-phenyltetrazolo[1,5-a]pyridine-6-carboxamide
Show/Hide
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C22H15F6N5O
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1
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| 1 |
IC50 = 279 nM
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CP0219915
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(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid 2-methoxy-benzyl ester
Show/Hide
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C24H28N2O5
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1
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| 1 |
IC50 = 280 nM
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CP0463573
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(S)-2-Hydroxymethyl-piperazine-1,4-dicarboxylic acid 4-dipentylamide 1-diphenylamide
Show/Hide
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C29H42N4O3
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1
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| 1 |
IC50 = 280 nM
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CP0432300
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-{[2-(benzyl-methyl-amino)-ethyl]-methyl-amide} 4-dipentylamide 1-diphenylamide
Show/Hide
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C40H56N6O3
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1
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| 1 |
IC50 = 290 nM
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CP0051512
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2-Benzyl-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C23H29NO
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1
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| 1 |
IC50 = 292 nM
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CP0416041
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N-(2,2-diphenylethyl)-N-methyl-3,5-bis(trifluoromethyl)benzamide
Show/Hide
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C24H19F6NO
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1
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| 1 |
IC50 = 297 nM
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CP0104164
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(2R,3R)-2-Benzhydryl-3-(3,5-bis-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C29H27F6NO
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1
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| 1 |
IC50 = 300 nM
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CP0454635
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2-Benzhydryl-3-(3-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C28H28F3NO
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1
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| 1 |
IC50 = 300 nM
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CP0374858
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(+/-)-cis-benzyl-3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentylcarbamate
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C28H25F6NO3
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1
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| 1 |
IC50 = 300 nM
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CP0427348
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N-[3,5-bis(trifluoromethyl)phenyl]-N-methyl-2,2-diphenylacetamide
Show/Hide
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C23H17F6NO
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1
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| 1 |
IC50 = 301 nM
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CP0445736
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N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-N-methyl-3,3-diphenylpropanamide
Show/Hide
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C27H25F6NO
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1
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| 1 |
IC50 = 304 nM
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CP0891048
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1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione
Show/Hide
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C28H21F6N3O2
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1
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| 1 |
IC50 = 310 nM
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CP0475269
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenyltetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
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C25H15F6N5O
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1
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| 1 |
IC50 = 311 nM
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CP0380459
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2-[3,5-bis(trifluoromethyl)phenoxy]-N-(4-fluorophenyl)-N-piperidin-4-ylacetamide
Show/Hide
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C21H19F7N2O2
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1
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| 1 |
IC50 = 316.23 nM
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CP0873839
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3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione
Show/Hide
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C21H15F6N3O2
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1
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| 1 |
IC50 = 317 nM
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CP0501597
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N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-N-methyl-2,2-diphenylacetamide
Show/Hide
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C26H23F6NO
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1
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| 1 |
IC50 = 323 nM
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CP0534244
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(S)-2-Benzylamino-3-(3,4-dichloro-benzyloxy)-1-(4-o-tolyl-piperidin-1-yl)-propan-1-one
Show/Hide
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C29H32Cl2N2O2
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1
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| 1 |
IC50 = 330 nM
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CP0454494
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1'N-[2-(1H-3-indolyl)-1-phenethylcarbamoyl-(1S)-ethyl]spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1'-carboxamide
Show/Hide
|
C33H36N4O2
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1
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| 1 |
IC50 = 332 nM
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CP0528911
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-methyl-1-oxido-4-phenylpyridin-1-ium-3-carboxamide
Show/Hide
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C22H16F6N2O2
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1
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| 1 |
IC50 = 342 nM
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CP0449656
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1-Benzyloxymethyl-2,2-diphenyl-ethylamine
Show/Hide
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C22H23NO
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2
|
| 1 |
IC50 = 367 nM
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| 2 |
IC50 = 400 nM
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CP0422393
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2-Benzhydryl-3-(4-trifluoromethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C28H28F3NO
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1
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| 1 |
IC50 = 370 nM
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CP0515963
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2-(3,5-Bis-trifluoromethyl-phenyl)-N-(2,2-diphenyl-ethyl)-acetamide
Show/Hide
|
C24H19F6NO
|
1
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| 1 |
IC50 = 378 nM
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CP0409437
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N-[[1-[(2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]propanoyl]-4-phenylpiperidin-4-yl]methyl]methanesulfonamide
Show/Hide
|
C30H35Cl2N3O4S
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1
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| 1 |
IC50 = 382 nM
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CP0522426
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenylpyrrolo[1,2-a]quinoline-4-carboxamide
Show/Hide
|
C28H18F6N2O
|
1
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| 1 |
IC50 = 390 nM
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CP0407762
|
1-[2-[(3-chlorophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
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C19H23ClN2O
|
2
|
| 1 |
IC50 = 398.11 nM
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| 2 |
Ki = 398.11 nM
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CP0448432
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1-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-piperazine-2,3-dione
Show/Hide
|
C22H17F6N3O2
|
1
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| 1 |
IC50 = 400 nM
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CP0506279
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-(4-methylphenyl)tetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
|
C26H17F6N5O
|
1
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| 1 |
IC50 = 401 nM
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CP0146713
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(S)-2-tert-Butoxycarbonylamino-3-(1H-indol-3-yl)-propionic acid benzyl ester
Show/Hide
|
C23H26N2O4
|
1
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| 1 |
IC50 = 413 nM
|
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CP0528914
|
2-Benzhydryl-3-(4-chloro-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
|
C27H28ClNO
|
1
|
| 1 |
IC50 = 417 nM
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CP0508277
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2,6-dimethyl-4-phenylpyridine-3-carboxamide
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C23H18F6N2O
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1
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| 1 |
IC50 = 434 nM
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CP0464142
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(3R,4S)-tert-butyl 3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl)-4-phenylpiperidine-1-carboxylate
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C26H28F6N2O3
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1
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| 1 |
IC50 = 450 nM
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CP0406117
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2-benzylamino-4-(3,4-dichlorophenyl)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-butanone
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C30H33Cl2N3O3S
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1
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| 1 |
IC50 = 455 nM
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CP0408580
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1'N-[1-benzyl(methyl)carbamoyl-2-benzyloxy-(1S)-ethyl]-1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1'-carboxamide
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C32H38N4O3S
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1
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| 1 |
IC50 = 480 nM
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CP0539773
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1-(3,5-Dimethyl-benzyloxymethyl)-2-phenyl-ethylamine
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C18H23NO
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1
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| 1 |
IC50 = 483 nM
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CP0534569
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1N,1N-dipentyl-4N,4N-diphenylhexahydro-1,4-pyrazinedicarboxamide
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C28H40N4O2
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1
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| 1 |
IC50 = 500 nM
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CP0395078
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5-(4-Fluoro-phenyl)-9-(3-trifluoromethyl-phenyl)-1,7-dioxa-4-aza-spiro[5.5]undecane
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C21H21F4NO2
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1
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| 1 |
IC50 = 513 nM
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CP0548993
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2,2-diphenylacetamide
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C23H17F6NO
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1
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| 1 |
IC50 = 526 nM
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CP0380762
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3-benzyloxy-2-(2-chlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
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C30H34ClN3O4S
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1
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| 1 |
IC50 = 542 nM
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CP0384625
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenyl-[1,2,4]triazolo[4,3-a]quinoline-4-carboxamide
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C26H16F6N4O
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1
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| 1 |
IC50 = 542 nM
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CP0498580
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N-[[1-[(2S)-2-(benzylamino)-3-[(3,4-dichlorophenyl)methoxy]propanoyl]piperidin-4-yl]methyl]-N-phenylmethanesulfonamide
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C30H35Cl2N3O4S
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1
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| 1 |
IC50 = 547 nM
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CP0123313
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(S)-2-Dimethylamino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
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C22H26N2O2
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1
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| 1 |
IC50 = 553 nM
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CP0518126
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(S)-2-Benzylamino-3-(3,4-dichloro-benzyloxy)-1-(4-o-tolyl-piperazin-1-yl)-propan-1-one
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C28H31Cl2N3O2
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1
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| 1 |
IC50 = 558 nM
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CP0440454
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3-[4-(3,5-Bis-trifluoromethyl-benzyl)-piperazin-2-ylmethyl]-1H-indole
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C22H21F6N3
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1
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| 1 |
IC50 = 567 nM
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CP0526675
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3-[4,6-Dichloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
Show/Hide
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C28H26Cl3N3O2
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1
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| 1 |
IC50 = 570 nM
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CP0495831
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N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-2,2-diphenylacetamide
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C25H21F6NO
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1
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| 1 |
IC50 = 593 nM
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CP0514439
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2-[[(2S)-4-(dipentylcarbamoyl)-1-(diphenylcarbamoyl)piperazine-2-carbonyl]amino]acetic acid
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C31H43N5O5
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1
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| 1 |
IC50 = 597 nM
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CP0506672
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2-benzylamino-3-(3,4-dichlorobenzyloxy)-1-spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl-(2S)-propan-1-one
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C30H32Cl2N2O2
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1
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| 1 |
IC50 = 602 nM
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CP0547734
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N-[3-[3,5-bis(trifluoromethyl)phenyl]propyl]-3,3-diphenylpropanamide
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C26H23F6NO
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1
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| 1 |
IC50 = 620 nM
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CP0508279
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-methyl-4-phenylpyridine-3-carboxamide
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C22H16F6N2O
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1
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| 1 |
IC50 = 653 nM
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CP0885648
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3-(3,5-Dimethyl-benzyl)-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
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C21H20N2O3
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1
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| 1 |
IC50 = 683 nM
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CP0501230
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-methyl-7-phenyl-[1,2,4]triazolo[4,3-a]pyridine-6-carboxamide
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C23H16F6N4O
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1
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| 1 |
IC50 = 698 nM
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CP0100923
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((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-phenethyl-amine
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C28H32N2
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1
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| 1 |
IC50 = 700 nM
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CP0520209
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4-Phenyl-4-(4-trifluoromethyl-benzyloxymethyl)-piperidine
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C20H22F3NO
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1
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| 1 |
IC50 = 730 nM
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CP0542918
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N-[(2S)-1-[(3,5-dimethylphenyl)methoxy]-3-(1H-indol-3-yl)propan-2-yl]acetamide
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C22H26N2O2
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1
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| 1 |
IC50 = 767 nM
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CP0384624
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N-[(3,5-dimethoxyphenyl)methyl]-5-phenyltetrazolo[1,5-a]quinoline-4-carboxamide
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C25H21N5O3
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1
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| 1 |
IC50 = 780 nM
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CP0102574
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N-[(2S)-4-(4-acetamido-4-phenylpiperidin-1-yl)-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide
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C31H35Cl2N3O2
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1
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| 1 |
IC50 = 800 nM
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CP0395120
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3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-tetrahydro-pyran
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C20H18F6O2
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1
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| 1 |
IC50 = 881 nM
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CP0381029
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3-benzyloxy-2-(2,6-dichlorobenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
Show/Hide
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C30H33Cl2N3O4S
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1
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| 1 |
IC50 = 895 nM
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CP0573142
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-[(2-dimethylamino-ethyl)-methyl-amide] 4-dipentylamide 1-diphenylamide
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C34H52N6O3
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1
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| 1 |
IC50 = 930 nM
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CP0107946
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4-(2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yloxymethyl)-benzonitrile
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C28H28N2O
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1
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| 1 |
IC50 = 950 nM
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CP0492134
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3-[4-Chloro-2-(4-chloro-phenyl)-1H-indol-3-yl]-1-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propan-1-one
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C28H27Cl2N3O2
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1
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| 1 |
IC50 = 950 nM
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CP0401151
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N-[(2S)-1-[(3,5-dimethylphenyl)methyl-methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]benzamide
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C28H29N3O2
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2
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| 1 |
IC50 = 1033 nM
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| 2 |
IC50 > 1100 nM
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CP0496746
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(S)-Piperazine-1,2,4-tricarboxylic acid 2-({2-[(3,5-bis-trifluoromethyl-benzyl)-methyl-amino]-ethyl}-methyl-amide) 4-dipentylamide 1-diphenylamide
Show/Hide
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C42H54F6N6O3
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1
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| 1 |
IC50 = 1080 nM
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CP0454574
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1'N-[1-benzyl(methyl)carbamoyl-3-phenyl-(1S)-propyl]-1-methylsulfanylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1'-carboxamide
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C32H38N4O2S
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1
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| 1 |
IC50 = 1100 nM
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CP0459928
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2-Benzhydryl-3-(4-methoxy-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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C28H31NO2
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1
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| 1 |
IC50 = 1113 nM
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CP0223214
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4-Benzyloxymethyl-4-phenyl-piperidine
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C19H23NO
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1
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| 1 |
IC50 = 1113 nM
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CP0511012
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1-(3,5-Dimethyl-benzyloxymethyl)-2-naphthalen-1-yl-ethylamine
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C22H25NO
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1
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| 1 |
IC50 = 1160 nM
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CP0423401
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-phenylimidazo[1,2-a]quinoline-4-carboxamide
Show/Hide
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C27H17F6N3O
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1
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| 1 |
IC50 = 1233 nM
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CP0535325
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N-(3,4-dichlorophenyl)-2-(3,5-difluorophenoxy)-N-piperidin-4-ylacetamide
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C19H18Cl2F2N2O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0498454
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1'-[2-(3,4-dichlorophenylcarboxamido)-3-[3,5-di(trifluoromethyl)benzyloxy]-(2S)-propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
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C32H29Cl2F6N3O5S
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1
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| 1 |
IC50 = 1300 nM
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CP0201374
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N-[(2S)-1-[(3,5-dimethylphenyl)methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]benzamide
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C27H27N3O2
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1
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| 1 |
IC50 = 1467 nM
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CP0103354
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(S)-2-Amino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
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C20H22N2O2
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1
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| 1 |
IC50 = 1533 nM
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CP0493052
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2-Amino-3-(1H-indol-3-yl)-propionic acid 3,5-dimethyl-benzyl ester
Show/Hide
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C20H22N2O2
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1
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| 1 |
IC50 = 1533 nM
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CP0543926
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1'-[3-benzyloxy-2-(3,4-dichlorophenylsulfonamido)propanoyl]-1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
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C23H29N3O4S
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1
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| 1 |
IC50 = 2000 nM
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CP0467113
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N-[(3,5-dimethoxyphenyl)methyl]-3,3-diphenylpropanamide
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C24H25NO3
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1
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| 1 |
IC50 = 2235 nM
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CP0528404
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1-(3,5-Dimethyl-benzyloxymethyl)-2-(1H-indol-3-yl)-ethylamine
Show/Hide
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C20H24N2O
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1
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| 1 |
IC50 = 2333 nM
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CP0535154
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1-(3,5-Dimethyl-benzyloxymethyl)-2-naphthalen-2-yl-ethylamine
Show/Hide
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C22H25NO
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1
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| 1 |
IC50 = 2333 nM
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CP0565983
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(R)-2-(3,5-Dimethyl-benzyloxy)-1-phenyl-ethylamine
Show/Hide
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C17H21NO
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1
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| 1 |
IC50 = 2500 nM
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CP0496426
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(S)-2-Benzylamino-3-(3,4-dichloro-benzyloxy)-1-(2-methanesulfonyl-2,8-diaza-spiro[4.5]dec-8-yl)-propan-1-one
Show/Hide
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C26H33Cl2N3O4S
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1
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| 1 |
IC50 = 2500 nM
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CP0521130
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1-((1S,2S)-2-Phenyl-cyclohexyloxymethyl)-3,5-bis-trifluoromethyl-benzene
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C21H20F6O
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1
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| 1 |
IC50 = 2632 nM
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CP0916802
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5-(1H-Indol-3-ylmethyl)-3-(3-trifluoromethyl-benzyl)-oxazolidine-2,4-dione
Show/Hide
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C20H15F3N2O3
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1
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| 1 |
IC50 = 2666 nM
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CP0509808
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N-[(2-methoxyphenyl)methyl]-5-phenyltetrazolo[1,5-a]quinoline-4-carboxamide
Show/Hide
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C24H19N5O2
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1
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| 1 |
IC50 = 2749 nM
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CP0160971
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2-Benzylidene-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
Show/Hide
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C23H27NO
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2
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| 1 |
IC50 = 2933 nM
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| 2 |
IC50 = 8200 nM
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CP0467024
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(R)-4-Dipentylcarbamoyl-1-diphenylcarbamoyl-piperazine-2-carboxylic acid
Show/Hide
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C29H40N4O4
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1
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| 1 |
IC50 = 3000 nM
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CP0509794
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N-[3,5-bis(trifluoromethyl)phenyl]-3,3-diphenylpropanamide
Show/Hide
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C23H17F6NO
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1
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| 1 |
IC50 = 3005 nM
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CP0060391
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3-(2,3-difluoro-4-methoxyphenyl)-2,5-dimethyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
Show/Hide
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C16H12F5N3O
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2
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| 1 |
IC50 = 3400 nM
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| 2 |
Ki = 650 nM
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CP0077914
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(S)-2-Ethylamino-3-(1H-indol-3-yl)-propionic acid benzyl ester
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C20H22N2O2
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1
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| 1 |
IC50 = 3800 nM
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CP0536147
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N-(2,2-diphenylethyl)-3,5-bis(trifluoromethyl)benzamide
Show/Hide
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C23H17F6NO
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1
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| 1 |
IC50 = 3917 nM
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CP0891131
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3-(3,5-Difluoro-benzyl)-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
Show/Hide
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C19H14F2N2O3
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1
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| 1 |
IC50 = 4275 nM
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CP0528840
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1-(3,5-Bis-trifluoromethyl-benzyl)-3-(1H-indol-3-ylmethyl)-piperazine-2,5-dione
Show/Hide
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C22H17F6N3O2
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1
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| 1 |
IC50 = 4333 nM
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CP0902699
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3-Benzyl-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
Show/Hide
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C19H16N2O3
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1
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| 1 |
IC50 = 6000 nM
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CP0504862
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N-[3,5-bis(trifluoromethyl)phenyl]-2,2-diphenylacetamide
Show/Hide
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C22H15F6NO
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1
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| 1 |
IC50 = 6561 nM
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CP0944909
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3-(3,5-Dimethoxy-benzyl)-5-(1H-indol-3-ylmethyl)-oxazolidine-2,4-dione
Show/Hide
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C21H20N2O5
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1
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| 1 |
IC50 = 7366 nM
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CP0100036
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(S)-2-Amino-3-(1H-indol-3-yl)-propionic acid benzyl ester
Show/Hide
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C18H18N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0393981
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2-Amino-3-(1H-indol-3-yl)-propionic acid benzyl ester
Show/Hide
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C18H18N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0088817
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C40H55N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0649061
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(5S,8S,14S,17S,20S,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0657579
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(5S,8S,14S,17S,20S,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0657580
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(R)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(oxalyl-amino)-butyric acid
Show/Hide
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C39H53N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0683920
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(R)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(oxalyl-amino)-succinamic acid
Show/Hide
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C38H51N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0683921
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(S)-5-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-5-(oxalyl-amino)-pentanoic acid
Show/Hide
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C40H55N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0695551
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(oxalyl-amino)-succinamic acid
Show/Hide
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C38H51N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0751077
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(S)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(oxalyl-amino)-butyric acid
Show/Hide
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C39H53N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0767142
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(S)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(3-carboxy-propionylamino)-butyric acid
Show/Hide
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C41H57N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0767143
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(S)-5-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-5-(3-carboxy-propionylamino)-pentanoic acid
Show/Hide
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C42H59N7O11S
|
1
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| 1 |
IC50 > 10000 nM
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CP0845710
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-20-(2-methoxy-2-oxoacetamido)-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C39H53N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0845712
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-(1H-indol-3-yl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C42H56N8O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0845715
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(5S,8S,14S,17S,20S,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C42H58N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0845717
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(5S,8S,14S,17S,20S,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C42H58N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0845718
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(R)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C40H55N7O11S
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0848393
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-propyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C36H55N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0850458
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(R)-4-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-phenyl-ethyl]-methyl-carbamoyl}-2-phenyl-ethylcarbamoyl)-4-(3-carboxy-propionylamino)-butyric acid
Show/Hide
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C41H57N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0852307
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(5S,8S,14S,17S,20R,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0852310
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(S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
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C40H55N7O12S
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1
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| 1 |
IC50 > 10000 nM
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|
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CP0852311
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-20-(3-hydroxyureido)-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C37H52N8O10S
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1
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| 1 |
IC50 > 10000 nM
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CP0852313
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(5S,8S,14S,17S,20S)-20-(2-amino-2-oxoacetamido)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C38H52N8O10S
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1
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| 1 |
IC50 > 10000 nM
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CP0852314
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(5S,8S,14S,17S,20R,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C42H58N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0852315
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(5S,8S,14S,17S,20S,23S)-23-amino-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C40H56N8O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0861325
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-20-ureido-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C37H52N8O9S
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1
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| 1 |
IC50 > 10000 nM
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CP0867813
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-20-(hydrazinecarboxamido)-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C37H53N9O9S
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1
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| 1 |
IC50 > 10000 nM
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CP0867814
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(5S,8S,14S,17S,20R,23S)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(2-carboxyethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C43H60N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0869123
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(5S,8S,14S,17S,20R,23R)-23-acetamido-14,17-dibenzyl-5-carbamoyl-20-(carboxymethyl)-8-isobutyl-15-methyl-7,10,13,16,19,22-hexaoxo-2-thia-6,9,12,15,18,21-hexaazapentacosan-25-oic acid
Show/Hide
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C42H58N8O12S
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1
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| 1 |
IC50 > 10000 nM
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CP0871268
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(5S,8S,14S,17S,20S)-14,17-dibenzyl-5-carbamoyl-8-isobutyl-15-methyl-7,10,13,16,19-pentaoxo-20-(sulfamoylamino)-2-thia-6,9,12,15,18-pentaazadocosan-22-oic acid
Show/Hide
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C36H52N8O10S2
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1
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| 1 |
IC50 > 10000 nM
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CP0894537
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(S)-N-((S)-1-{[(1S,2S)-1-({[(S)-1-((S)-1-Carbamoyl-3-methylsulfanyl-propylcarbamoyl)-3-methyl-butylcarbamoyl]-methyl}-carbamoyl)-2-methyl-butyl]-methyl-carbamoyl}-2-phenyl-ethyl)-3-(3-carboxy-propionylamino)-succinamic acid
Show/Hide
|
C37H57N7O11S
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1
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| 1 |
IC50 > 10000 nM
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CP0520278
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(2-Methoxy-benzyl)-(4-phenyl-piperidin-4-ylmethyl)-amine
Show/Hide
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C20H26N2O
|
1
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| 1 |
IC50 > 100 nM
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CP0918849
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2-[3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-cyclohexyl]-acetamide
Show/Hide
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C23H23F6NO2
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1
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| 1 |
IC50 >= 157 nM
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CP0044053
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Benzoic acid (2S,3S)-2-benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl ester
Show/Hide
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C27H27NO2
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1
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| 1 |
IC50 > 1000 nM
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CP0181993
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1-((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-3-phenyl-thiourea
Show/Hide
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C27H29N3S
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1
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| 1 |
IC50 > 1000 nM
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CP0295947
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N-[(2S,3S)-2-benzhydryl-1-azabicyclo[2.2.2]octan-3-yl]benzamide
Show/Hide
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C27H28N2O
|
1
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| 1 |
IC50 > 1000 nM
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CP0296048
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((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-carbamic acid phenyl ester
Show/Hide
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C27H28N2O2
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1
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| 1 |
IC50 > 1000 nM
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CP0307689
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[(2S,3S)-2-benzhydryl-1-azabicyclo[2.2.2]octan-3-yl] N-phenylcarbamate
Show/Hide
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C27H28N2O2
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1
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| 1 |
IC50 > 1000 nM
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CP0339065
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1-((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl)-3-phenyl-urea
Show/Hide
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C27H29N3O
|
1
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| 1 |
IC50 > 1000 nM
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CP0540981
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N-[(2S,3S)-2-benzhydryl-1-azabicyclo[2.2.2]octan-3-yl]benzenesulfonamide
Show/Hide
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C26H28N2O2S
|
1
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| 1 |
IC50 > 1000 nM
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CP0147399
|
VESTIPITANT
Show/Hide
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C23H24F7N3O
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2
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| 1 |
Kd = 0.0302 nM
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| 2 |
Ki = 0.2239 nM
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CP0894612
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1-[(R)-4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-propan-2-one O-[2-(1,1-dioxo-thiomorpholin-4-yl)-ethyl]-oxime
Show/Hide
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C31H35F6N5O4S
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2
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| 1 |
Kd = 0.1 nM
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| 2 |
Ki = 2.512 nM
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CP0860922
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-morpholinoethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C31H35F6N5O3
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2
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| 1 |
Kd = 0.1585 nM
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| 2 |
Ki = 10 nM
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CP0894609
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-aminoethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C27H29F6N5O2
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2
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| 1 |
Kd = 0.1585 nM
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| 2 |
Ki = 0.7943 nM
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CP0894611
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(3-morpholinopropoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C32H37F6N5O3
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2
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| 1 |
Kd = 0.1585 nM
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| 2 |
Ki = 12.59 nM
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CP0868699
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-(methylamino)ethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C28H31F6N5O2
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2
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| 1 |
Kd = 0.3162 nM
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| 2 |
Ki = 1.995 nM
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CP0883120
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[(R)-4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-acetaldehyde O-(2-morpholin-4-yl-ethyl)-oxime
Show/Hide
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C30H33F6N5O3
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2
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| 1 |
Kd = 0.631 nM
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| 2 |
Ki = 1.259 nM
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CP0889517
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((R)-2-((1H-indol-3-yl)methyl)-4-((5-(morpholinomethyl)-4,5-dihydroisoxazol-3-yl)methyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C31H33F6N5O3
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2
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| 1 |
Kd = 0.631 nM
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| 2 |
Ki = 2.512 nM
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CP0904893
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[(R)-4-(3,5-bis-trifluoromethyl-benzoyl)-3-(1H-indol-3-ylmethyl)-piperazin-1-yl]-acetaldehyde O-(3-morpholin-4-yl-propyl)-oxime
Show/Hide
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C31H35F6N5O3
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2
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| 1 |
Kd = 0.631 nM
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| 2 |
Ki = 1.259 nM
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CP0889516
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(R)-(2-((1H-indol-3-yl)methyl)-4-((5-(morpholinomethyl)isoxazol-3-yl)methyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C31H31F6N5O3
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2
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| 1 |
Kd = 0.7943 nM
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| 2 |
Ki = 12.59 nM
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CP0860921
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(R)-(2-((1H-indol-3-yl)methyl)-4-(3-(3-morpholinopropoxyimino)butyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C33H39F6N5O3
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2
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| 1 |
Kd = 1 nM
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| 2 |
Ki = 0.1995 nM
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CP0868701
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(pyridin-2-ylmethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C31H29F6N5O2
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 10 nM
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CP0881283
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(R)-3-((1H-indol-3-yl)methyl)-N-(2-(2-methoxybenzylamino)ethyl)-4-(3,5-bis(trifluoromethyl)benzoyl)piperazine-1-carboxamide
Show/Hide
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C33H33F6N5O3
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 2.512 nM
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CP0883121
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(R)-(2-((1H-indol-3-yl)methyl)-4-(3-(2-morpholinoethoxyimino)-3-phenylpropyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C37H39F6N5O3
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 10 nM
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CP0904894
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(3-morpholinopropoxyimino)-2-phenylethyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C37H39F6N5O3
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 6.31 nM
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CP0920952
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(R)-(2-((1H-indol-3-yl)methyl)-4-(3-(2-morpholinoethoxyimino)butyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C32H37F6N5O3
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 0.3981 nM
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CP0925495
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-thiomorpholinoethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C31H35F6N5O2S
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2
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| 1 |
Kd = 1.259 nM
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| 2 |
Ki = 6.31 nM
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CP0870989
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-(4-methylpiperazin-1-yl)ethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C32H38F6N6O2
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2
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| 1 |
Kd = 1.585 nM
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| 2 |
Ki = 1.585 nM
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CP0870990
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(R)-(2-((1H-indol-3-yl)methyl)-4-(4-(2-morpholinoethoxyimino)pentyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C33H39F6N5O3
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2
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| 1 |
Kd = 1.585 nM
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| 2 |
Ki = 1.259 nM
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CP0918948
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((R)-2-((1H-indol-3-yl)methyl)-4-((Z)-2-(2-morpholinopropoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C32H37F6N5O3
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2
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| 1 |
Kd = 1.995 nM
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| 2 |
Ki = 3.162 nM
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CP0894610
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-morpholinoethoxyimino)-2-phenylethyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C36H37F6N5O3
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2
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| 1 |
Kd = 3.162 nM
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| 2 |
Ki = 19.95 nM
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CP0246871
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(S)-2-(4-acetamido-3-oxo-4,5-dihydro-1H-benzo[c]azepin-2(3H)-yl)-N-(3,5-bis(trifluoromethyl)benzyl)-N-methylacetamide
Show/Hide
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C24H23F6N3O3
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2
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| 1 |
Kd = 3.981 nM
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| 2 |
Ki = 27 nM
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CP0868698
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-methyl-2-morpholinopropoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C33H39F6N5O3
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2
|
| 1 |
Kd = 5.012 nM
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| 2 |
Ki = 6.31 nM
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CP0881284
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(methoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
|
C26H26F6N4O2
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2
|
| 1 |
Kd = 7.943 nM
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| 2 |
Ki = 3.981 nM
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CP0922786
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(R)-(2-((1H-indol-3-yl)methyl)-4-(2-(2-(dimethylamino)ethoxyimino)propyl)piperazin-1-yl)(3,5-bis(trifluoromethyl)phenyl)methanone
Show/Hide
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C29H33F6N5O2
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2
|
| 1 |
Kd = 7.943 nM
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| 2 |
Ki = 0.7943 nM
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CP0366288
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(R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-2-(2-((3,5-bis(trifluoromethyl)benzyl)(methyl)amino)-2-oxoethyl)-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-yl)-5-guanidinopentanamide
Show/Hide
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C39H46F6N8O5
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2
|
| 1 |
Kd = 15.85 nM
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| 2 |
Ki = 0.5 nM
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CP0246872
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[benzyl(methyl)amino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C38H50N8O5
|
2
|
| 1 |
Kd = 363.08 nM
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|
| 2 |
Ki = 13 nM
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CP0302593
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[[3,5-bis(trifluoromethyl)phenyl]methyl-methylamino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(carbamoylamino)pentanamide
Show/Hide
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C40H47F6N7O6
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2
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| 1 |
Kd = 537.03 nM
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| 2 |
Ki = 34.7 nM
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CP0389566
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[[3,5-bis(trifluoromethyl)phenyl]methyl-methylamino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C40H48F6N8O5
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2
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| 1 |
Kd = 912.01 nM
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| 2 |
Ki = 59.7 nM
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CP0078359
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C34H34F6N4O5
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1
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| 1 |
Ki = 0.016 nM
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CP0498166
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(R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-phenylcyclobutanamine
Show/Hide
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C21H21F6NO
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1
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| 1 |
Ki = 0.02 nM
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CP0889328
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(2S,3S)-N-(2-Methoxy-5-(5-(trifluoromethyl)-1H-tetrazol-1-yl)benzyl)-2-phenylpiperidin-3-amine dihydrchloride
Show/Hide
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C21H25Cl2F3N6O
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1
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| 1 |
Ki = 0.02512 nM
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CP0068481
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C34H33F6N5O6
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1
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| 1 |
Ki = 0.03 nM
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CP0452873
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(2S,3S)-N-[(2-methoxy-5-thiophen-3-ylphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C23H26N2OS
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1
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| 1 |
Ki = 0.03162 nM
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CP0404126
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C57H67F6N9O10S
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1
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| 1 |
Ki = 0.034 nM
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CP0409461
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(2S,3S)-N-[[2-methoxy-5-(5-propyltetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C23H32Cl2N6O
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1
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| 1 |
Ki = 0.03981 nM
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CP0516077
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(2S,3S)-N-[[2-methoxy-5-(5-methylsulfanyltetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C21H28Cl2N6OS
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1
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| 1 |
Ki = 0.03981 nM
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CP0683998
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(2S,3S)-N-(2-methoxy-5-(1H-tetrazol-1-yl)benzyl)-2-phenylpiperidin-3-amine dihydrochloride
Show/Hide
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C20H26Cl2N6O
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1
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| 1 |
Ki = 0.03981 nM
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CP0394033
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C-terminal modified bifunctional peptide, 1
Show/Hide
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C54H60F6N8O9
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1
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| 1 |
Ki = 0.046 nM
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CP0146784
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[3-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]propanoylamino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C46H47F6N7O8
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1
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| 1 |
Ki = 0.05 nM
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CP0481049
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(2S,3S)-N-[(5-bromo-2-methoxyphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C19H23BrN2O
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1
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| 1 |
Ki = 0.05012 nM
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CP0481058
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(2S,3S)-N-[[5-(3,5-dimethyl-1,2-oxazol-4-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C24H29N3O2
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1
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| 1 |
Ki = 0.05012 nM
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CP0509116
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(2S,3S)-N-[[5-(5-ethyltetrazol-1-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C22H30Cl2N6O
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1
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| 1 |
Ki = 0.05012 nM
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CP0548571
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(2S,3S)-N-[[2-methoxy-5-(5-methyltetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C21H28Cl2N6O
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1
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| 1 |
Ki = 0.05012 nM
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CP0436817
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(2S,3S)-N-[(2-methoxy-5-pyridin-4-ylphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C24H27N3O
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1
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| 1 |
Ki = 0.0631 nM
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CP0520251
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(2S,3S)-N-[[5-(furan-3-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C23H26N2O2
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1
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| 1 |
Ki = 0.0631 nM
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CP0496860
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(2S,3S)-N-[[2-methoxy-5-(5-methylsulfonyltetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C21H28Cl2N6O3S
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1
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| 1 |
Ki = 0.0631 nM
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CP0313996
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[1-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]cyclopentanecarbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C60H71F6N9O10S
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1
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| 1 |
Ki = 0.066 nM
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CP0419390
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(2S,3S)-N-[(2-methoxy-5-methylsulfanylphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C20H26N2OS
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1
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| 1 |
Ki = 0.07943 nM
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CP0453939
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(2S,3S)-N-[[5-(5-cyclopropyltetrazol-1-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C23H30Cl2N6O
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1
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| 1 |
Ki = 0.07943 nM
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CP0381239
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(2R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-4-(dimethylamino)-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C25H28F7N3O
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1
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| 1 |
Ki = 0.07943 nM
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CP0512997
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(2R,4S)-4-(azetidin-1-yl)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C26H28F7N3O
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1
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| 1 |
Ki = 0.08128 nM
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CP0313995
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C48H51F6N7O8S
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1
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| 1 |
Ki = 0.09 nM
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CP0244494
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-1-[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C48H49F6N7O8
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1
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| 1 |
Ki = 0.097 nM
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CP0496842
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N-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]acetamide
Show/Hide
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C23H23F6NO2
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1
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| 1 |
Ki = 0.1 nM
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CP0499552
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(2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C29H33F7N4O2
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1
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| 1 |
Ki = 0.1175 nM
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CP0419819
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-2-methylpropanoyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C58H69F6N9O10S
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1
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| 1 |
Ki = 0.12 nM
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CP0066825
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C43H42F6N6O7
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1
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| 1 |
Ki = 0.12 nM
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CP0466999
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(2S,3S)-N-[[2-methoxy-5-(tetrazol-2-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C20H24N6O
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1
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| 1 |
Ki = 0.1259 nM
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CP0549326
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(2R,4S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-4-pyrrolidin-1-ylpiperidine-1-carboxamide
Show/Hide
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C28H32F7N3O
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1
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| 1 |
Ki = 0.1413 nM
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CP0067161
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]acetamide
Show/Hide
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C24H26F6N2O2
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1
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| 1 |
Ki = 0.15 nM
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CP0523370
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(2S,3S)-N-[(5-fluoro-2-methoxyphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C19H23FN2O
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1
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| 1 |
Ki = 0.1585 nM
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CP0532082
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(2S,3S)-N-[(2-methoxy-5-pyrimidin-5-ylphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C23H26N4O
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1
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| 1 |
Ki = 0.1585 nM
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CP0547695
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(2S,3S)-N-[[2-methoxy-5-(1,2,4-triazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C21H25N5O
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1
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| 1 |
Ki = 0.1585 nM
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CP0506038
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(2R,4S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-4-(cyclobutylamino)-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C28H32F7N3O
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1
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| 1 |
Ki = 0.1698 nM
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CP0381240
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(2R,4S)-4-(azetidin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C27H30F7N3O
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1
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| 1 |
Ki = 0.1778 nM
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CP0505964
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(3R,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-6-phenylpiperidine-3-carboxamide
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
Ki = 0.19 nM
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CP0414859
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(2S,3S)-N-[[2-methoxy-5-(1-methyltetrazol-5-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C21H26N6O
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1
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| 1 |
Ki = 0.1995 nM
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CP0378644
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(2R,4R)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-4-pyrrolidin-1-ylpiperidine-1-carboxamide
Show/Hide
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C28H32F7N3O
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1
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| 1 |
Ki = 0.1995 nM
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CP0378878
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(2R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-4-(methylamino)piperidine-1-carboxamide
Show/Hide
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C24H26F7N3O
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1
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| 1 |
Ki = 0.1995 nM
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CP0503240
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1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-oxo-5-phenylpyrrolidin-3-yl)piperidin-2-one
Show/Hide
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C26H26F6N2O3
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1
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| 1 |
Ki = 0.2 nM
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CP0504317
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1-((3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-oxo-5-phenylpyrrolidin-3-yl)pyrrolidin-2-one
Show/Hide
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C25H24F6N2O3
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1
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| 1 |
Ki = 0.2 nM
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CP0541240
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1-((3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-oxo-5-phenylpyrrolidin-3-yl)piperidin-2-one
Show/Hide
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C26H26F6N2O3
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1
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| 1 |
Ki = 0.2 nM
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CP0141881
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-fluorophenyl)propanoate
Show/Hide
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C32H31F7N4O6
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1
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| 1 |
Ki = 0.2 nM
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CP0549329
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(2R,4S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-4-(2-methoxyethylamino)-N-methylpiperidine-1-carboxamide
Show/Hide
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C27H32F7N3O2
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1
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| 1 |
Ki = 0.2089 nM
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CP0406090
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(3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-6-phenylpiperidine-3-carboxamide
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
Ki = 0.22 nM
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CP0488808
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]cyclopropanecarboxamide
Show/Hide
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C26H28F6N2O2
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1
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| 1 |
Ki = 0.23 nM
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CP0499551
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(2R,4S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-4-(dimethylamino)-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C26H30F7N3O
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1
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| 1 |
Ki = 0.2399 nM
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CP0469361
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N-[1-[4-methoxy-3-[[[(2S,3S)-2-phenylpiperidin-3-yl]amino]methyl]phenyl]tetrazol-5-yl]acetamide;dihydrochloride
Show/Hide
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C22H29Cl2N7O2
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1
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| 1 |
Ki = 0.2512 nM
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CP0379539
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(3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-methyl-6-phenylpiperidine-3-carboxamide
Show/Hide
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C24H26F6N2O2
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1
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| 1 |
Ki = 0.26 nM
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CP0504371
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1-((3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-6-phenylpiperidin-3-yl)pyrrolidin-2-one
Show/Hide
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C26H28F6N2O2
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1
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| 1 |
Ki = 0.26 nM
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CP0469268
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(2R,4S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methyl-4-pyrrolidin-1-ylpiperidine-1-carboxamide
Show/Hide
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C27H30F7N3O
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1
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| 1 |
Ki = 0.2754 nM
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CP0511811
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]-4,5-dihydro-1,3-oxazol-2-amine
Show/Hide
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C25H27F6N3O2
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1
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| 1 |
Ki = 0.28 nM
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CP0502481
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]propanamide
Show/Hide
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C25H28F6N2O2
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1
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| 1 |
Ki = 0.29 nM
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CP0467123
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N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
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C31H38Cl4N6O4
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1
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| 1 |
Ki = 0.3 nM
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CP0441683
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(R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-benzyl-3-phenylcyclobutanamine
Show/Hide
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C28H27F6NO
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1
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| 1 |
Ki = 0.3 nM
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CP0453008
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1-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]pyrrolidin-2-one
Show/Hide
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C25H25F6NO2
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1
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| 1 |
Ki = 0.3 nM
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CP0399284
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N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]acetamide
Show/Hide
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C23H22F6N2O3
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1
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| 1 |
Ki = 0.3 nM
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CP0444656
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N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]propanamide
Show/Hide
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C24H24F6N2O3
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1
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| 1 |
Ki = 0.3 nM
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CP0504318
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N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]propanamide
Show/Hide
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C24H24F6N2O3
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1
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| 1 |
Ki = 0.3 nM
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CP0385728
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(S)-2-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-phenylpiperidine
Show/Hide
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C22H23F6NO
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1
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| 1 |
Ki = 0.3 nM
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CP0517243
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(2R,4S)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-4-(cyclopropylamino)-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C27H30F7N3O
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1
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| 1 |
Ki = 0.3236 nM
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CP0410098
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]pyrimidin-2-amine
Show/Hide
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C26H26F6N4O
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1
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| 1 |
Ki = 0.33 nM
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CP0077727
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(2R,4S)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C30H35F7N4O2
|
1
|
| 1 |
Ki = 0.3311 nM
|
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CP0488809
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(3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-cyclopropyl-6-phenylpiperidine-3-carboxamide
Show/Hide
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C26H28F6N2O2
|
1
|
| 1 |
Ki = 0.34 nM
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CP0146998
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]hexanoylamino]-3-(1H-indol-3-yl)propanoate
Show/Hide
|
C49H53F6N7O8
|
1
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| 1 |
Ki = 0.34 nM
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CP0527200
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N-[(3R,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]acetamide
Show/Hide
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C24H26F6N2O2
|
1
|
| 1 |
Ki = 0.35 nM
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CP0439553
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(3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-ethyl-6-phenylpiperidine-3-carboxamide
Show/Hide
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C25H28F6N2O2
|
1
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| 1 |
Ki = 0.37 nM
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CP0463732
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(2S,3S)-N-[[2-methoxy-5-(5-phenyltetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C26H30Cl2N6O
|
1
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| 1 |
Ki = 0.3981 nM
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CP0464148
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C30H37Cl4N5O3
|
1
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| 1 |
Ki = 0.4 nM
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CP0506061
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3,5-Dichloro-N-[(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-N-hydroxycarbamimidoylmethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C31H38Cl4N6O4
|
1
|
| 1 |
Ki = 0.4 nM
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CP0483577
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2-((R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-(4-fluorophenyl)-2-oxoimidazolidin-1-yl)acetamide
Show/Hide
|
C22H20F7N3O3
|
1
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| 1 |
Ki = 0.4 nM
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|
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CP0483578
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4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)-1-(1-methylpiperidin-4-yl)imidazolidin-2-one
Show/Hide
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C25H26F7N3O2
|
1
|
| 1 |
Ki = 0.4 nM
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CP0376363
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N-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]acetamide
Show/Hide
|
C23H23F6NO2
|
1
|
| 1 |
Ki = 0.4 nM
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|
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CP0395375
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1-[3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]pyrrolidin-2-one
Show/Hide
|
C25H25F6NO2
|
1
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| 1 |
Ki = 0.4 nM
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CP0453554
|
2-(3,5-bis(trifluoromethyl)phenyl)-N-(6-(4-hydroxypiperidin-1-yl)-4-o-tolylpyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
|
C30H31F6N3O2
|
1
|
| 1 |
Ki = 0.4 nM
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CP0494675
|
(5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-amino-5-phenylpyrrolidin-2-one
Show/Hide
|
C21H20F6N2O2
|
1
|
| 1 |
Ki = 0.4 nM
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|
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CP0522757
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(3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-5-phenyl-3-(pyrrolidin-1-yl)pyrrolidin-2-one
Show/Hide
|
C25H26F6N2O2
|
1
|
| 1 |
Ki = 0.4 nM
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|
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CP0410100
|
(3R,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-cyclopropyl-6-phenylpiperidine-3-carboxamide
Show/Hide
|
C26H28F6N2O2
|
1
|
| 1 |
Ki = 0.4 nM
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|
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CP0374459
|
(2S)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine-1-carboxamide
Show/Hide
|
C22H22F7N3O
|
1
|
| 1 |
Ki = 0.4266 nM
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CP0421368
|
1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutane-1-carboxamide
Show/Hide
|
C22H22F6N2O2
|
1
|
| 1 |
Ki = 0.43 nM
|
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CP0517242
|
(2R,4R)-4-(4-acetylpiperazin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
|
C30H35F7N4O2
|
1
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| 1 |
Ki = 0.4365 nM
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|
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CP0460154
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(2-(4-methylpiperazin-1-yl)-4-o-tolylpyrimidin-5-yl)propanamide
Show/Hide
|
C29H31F6N5O
|
1
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| 1 |
Ki = 0.44 nM
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|
|
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CP0385820
|
[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-chlorophenyl)propanoyl]amino]acetyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
|
C45H44ClF6N7O8
|
1
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| 1 |
Ki = 0.47 nM
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CP0406314
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-hydroxy-2-methyl-propyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H43Cl4N5O4
|
1
|
| 1 |
Ki = 0.5 nM
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|
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CP0372998
|
3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-2-[(Z)-2-piperazin-1-yl-ethoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C35H46Cl4N6O3
|
1
|
| 1 |
Ki = 0.5 nM
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|
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CP0497478
|
(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-1-methyl-4-phenylimidazolidin-2-one
Show/Hide
|
C21H20F6N2O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
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CP0449436
|
1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-3-phenylcyclobutane-1-carboxamide
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
Ki = 0.5 nM
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|
|
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CP0510270
|
(R)-5-((3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-phenylcyclobutylamino)methyl)-2H-1,2,4-triazol-3(4H)-one
Show/Hide
|
C24H24F6N4O2
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
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CP0494673
|
1-((3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-2-oxo-5-phenylpyrrolidin-3-yl)pyrrolidin-2-one
Show/Hide
|
C25H24F6N2O3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
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CP0526172
|
(5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-hydroxy-5-phenylpyrrolidin-2-one
Show/Hide
|
C21H19F6NO3
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
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CP0222207
|
(2S,3S)-N-[(2-methoxy-5-methylsulfonylphenyl)methyl]-2-phenylpiperidin-3-amine
Show/Hide
|
C20H26N2O3S
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
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CP0439691
|
(2S,3S)-N-[[5-(furan-2-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
Ki = 0.5012 nM
|
|
|
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CP0406062
|
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2S,4S)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
|
C29H28ClF6N3O3
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0915544
|
acetic acid;(2S)-N-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine-1-carboxamide
Show/Hide
|
C25H28F7N3O3
|
1
|
| 1 |
Ki = 0.537 nM
|
|
|
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CP0505533
|
(3R,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-methyl-6-phenylpiperidine-3-carboxamide
Show/Hide
|
C24H26F6N2O2
|
1
|
| 1 |
Ki = 0.56 nM
|
|
|
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CP0371765
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide
Show/Hide
|
C28H28F6N4O
|
1
|
| 1 |
Ki = 0.58 nM
|
|
|
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CP0375903
|
1-((3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-6-phenylpiperidin-3-yl)imidazolidin-2-one
Show/Hide
|
C25H27F6N3O2
|
1
|
| 1 |
Ki = 0.59 nM
|
|
|
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CP0394239
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-methanesulfonylamino-ethyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C32H42Cl4N6O5S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0403323
|
N-[(2Z,3R)-5-[4-[3-[(2R)-1-amino-3-hydroxy-1-oxopropan-2-yl]-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C32H40Cl4N6O5
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0536011
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(N-hydroxycarbamimidoylmethyl)-2-oxo-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C31H39Cl4N7O4
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0520844
|
3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-2-hydroxy-ethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C31H38Cl4N4O4
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0398466
|
(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-phenylimidazolidin-2-one
Show/Hide
|
C20H18F6N2O2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0486827
|
(S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-5-phenylpyrrolidin-2-one
Show/Hide
|
C21H19F6NO2
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0522759
|
N-[(3S,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]methanesulfonamide
Show/Hide
|
C22H22F6N2O4S
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0388685
|
(3R,4S)-3-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(4-fluorophenyl)-N-(2-hydroxyethyl)pyrrolidine-1-carboxamide
Show/Hide
|
C26H28F7N3O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0043850
|
(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-({[3,5-bis(trifluoromethyl)phenyl]methyl}carbamoyl)-2-(1H-indol-3-yl)ethyl]-4-methylpentanamide
Show/Hide
|
C54H61F6N9O8
|
2
|
| 1 |
Ki = 0.6 nM
|
|
|
| 2 |
Ki = 0.61 nM
|
|
|
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CP0452244
|
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
|
C29H28ClF6N3O3
|
1
|
| 1 |
Ki = 0.61 nM
|
|
|
|
CP0549325
|
(2R,4R)-4-(azetidin-1-yl)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
|
C27H30F7N3O
|
1
|
| 1 |
Ki = 0.6457 nM
|
|
|
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CP0410097
|
1-((3S,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-6-phenylpiperidin-3-yl)urea
Show/Hide
|
C23H25F6N3O2
|
1
|
| 1 |
Ki = 0.69 nM
|
|
|
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CP0343091
|
2-[(1R,2S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butylamino]-acetamide
Show/Hide
|
C33H35Cl2F6N3O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0506846
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-ylmethyl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C35H40Cl4N6O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0377367
|
3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-N-hydroxycarbamimidoylmethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C31H38Cl4N6O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0378688
|
3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-2-[(Z)-3-[1,2,4]triazol-1-yl-propoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C34H41Cl4N7O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0382342
|
2-[(Z)-[1-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentan-2-ylidene]amino]oxyacetic acid
Show/Hide
|
C31H36Cl4N4O5
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0449887
|
3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-hydroxy-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C32H40Cl4N4O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0464438
|
N-[(2Z)-2-(3-aminopropoxyimino)-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C32H41Cl4N5O3
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0494674
|
(3S,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-methyl-5-phenylpyrrolidin-2-one
Show/Hide
|
C22H21F6NO2
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0520519
|
2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2-hydroxyethyl)(methyl)amino)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
|
C27H26ClF6N3O2
|
1
|
| 1 |
Ki = 0.78 nM
|
|
|
|
CP0401672
|
(2S,3S)-N-[[2-methoxy-5-(1,3-thiazol-2-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
|
C22H25N3OS
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0458847
|
(2S,3S)-N-[[2-methoxy-5-(1,3,5-trimethylpyrazol-4-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
|
C25H32N4O
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0409122
|
N-[(2Z,3R)-5-[4-[3-(1-amino-2-methyl-1-oxopropan-2-yl)-2-oxo-1,3-diazinan-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
|
C33H42Cl4N6O4
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0464095
|
3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-morpholin-4-yl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H42Cl4N6O4
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0378728
|
3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-methanesulfinyl-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C33H42Cl4N4O4S
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0404221
|
3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-2-[(Z)-3-tetrazol-1-yl-propoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
|
C33H40Cl4N8O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0445490
|
3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-fluoromethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
|
C30H35Cl4FN4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0494666
|
(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-1-ethyl-4-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C22H21F7N2O2
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0385819
|
(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-(1H-indol-3-yl)propanamide
Show/Hide
|
C34H35F6N5O4
|
1
|
| 1 |
Ki = 0.85 nM
|
|
|
|
CP0504348
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((S)-3-hydroxypyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
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C28H26ClF6N3O2
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1
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| 1 |
Ki = 0.86 nM
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CP0368138
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[3,5-bis(trifluoromethyl)phenyl]methyl (2S)-2-[[(2S)-2-[[(2R)-1-[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoate
Show/Hide
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C59H69F6N9O10S
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1
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| 1 |
Ki = 0.88 nM
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CP0412079
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-isopropyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
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C32H41Cl4N5O3
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1
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| 1 |
Ki = 0.9 nM
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CP0424454
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methylcarbamoylmethyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
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C32H40Cl4N6O4
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1
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| 1 |
Ki = 0.9 nM
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CP0511420
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2-(1-Benzyl-piperidin-4-ylamino)-1-[(S)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
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C33H38Cl2N4O2
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1
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| 1 |
Ki = 0.9 nM
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CP0404410
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N-[(2Z)-2-(2-amino-2-oxoethoxy)imino-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-3,5-dichloro-N-methylbenzamide
Show/Hide
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C31H37Cl4N5O4
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1
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| 1 |
Ki = 0.9 nM
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CP0517945
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-methanesulfonyl-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H42Cl4N4O5S
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1
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| 1 |
Ki = 0.9 nM
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CP0554283
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4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)-1-(piperidin-4-yl)imidazolidin-2-one
Show/Hide
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C24H24F7N3O2
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1
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| 1 |
Ki = 0.9 nM
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CP0452527
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N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]acetamide
Show/Hide
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C23H22F6N2O3
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1
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| 1 |
Ki = 0.9 nM
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CP0388684
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2-(3,5-bis(trifluoromethyl)phenyl)-N-((3R,4S)-4-(4-fluorophenyl)pyrrolidin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C23H23F7N2O
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1
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| 1 |
Ki = 0.9 nM
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CP0372174
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2S,4R)-4-methoxy-2-(methoxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C31H32ClF6N3O3
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1
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| 1 |
Ki = 0.91 nM
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CP0424252
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(2R,4R)-N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-4-(dimethylamino)-2-(4-fluoro-2-methylphenyl)-N-methylpiperidine-1-carboxamide
Show/Hide
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C26H30F7N3O
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1
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| 1 |
Ki = 0.9333 nM
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CP0147398
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-4-o-tolylpyridin-3-yl)propanamide
Show/Hide
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C30H32F6N4O
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1
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| 1 |
Ki = 0.95 nM
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CP0404408
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(2R)-N-[(2S)-1-[[(2S)-6-amino-1-[4-[(3S,4R)-1-[3,5-bis(trifluoromethyl)benzoyl]-3-phenylpiperidin-4-yl]piperazin-1-yl]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C56H71F6N11O6
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1
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| 1 |
Ki = 0.99 nM
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CP0529598
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(2S,3S)-N-[[5-(5-aminotetrazol-1-yl)-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
Show/Hide
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C20H27Cl2N7O
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1
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| 1 |
Ki = 1 nM
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CP0380707
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3,5-Dichloro-N-((R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-{4-[2-oxo-3-(2H-tetrazol-5-ylmethyl)-tetrahydro-pyrimidin-1-yl]-piperidin-1-yl}-pentyl)-N-methyl-benzamide
Show/Hide
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C31H37Cl4N9O3
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1
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| 1 |
Ki = 1 nM
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CP0404000
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-hydroxy-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
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C29H35Cl4N5O4
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1
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| 1 |
Ki = 1 nM
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CP0439307
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benzyl 2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxo-1,3-diazinan-1-yl]acetate
Show/Hide
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C38H43Cl4N5O5
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1
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| 1 |
Ki = 1 nM
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CP0524089
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-(3-methyl-ureido)-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C34H44Cl4N6O4
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1
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| 1 |
Ki = 1 nM
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CP0532722
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(2-methylphenyl)ethyl]piperazine
Show/Hide
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C22H24F6N2O
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1
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| 1 |
Ki = 1 nM
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CP0395366
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1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutane-1-carboxamide
Show/Hide
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C22H22F6N2O2
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1
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| 1 |
Ki = 1 nM
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CP0442833
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1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N-methyl-3-phenylcyclobutane-1-carboxamide
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
Ki = 1 nM
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CP0449704
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-morpholino-4-o-tolylpyridin-3-yl)propanamide
Show/Hide
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C29H29F6N3O2
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1
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| 1 |
Ki = 1 nM
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CP0421692
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((S)-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C29H28ClF6N3O2
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1
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| 1 |
Ki = 1 nM
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CP0206724
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-fluorophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H64F7N9O8
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1
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| 1 |
Ki = 1 nM
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CP0406089
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N-[(3S,6S)-6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-6-phenylpiperidin-3-yl]methanesulfonamide
Show/Hide
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C23H26F6N2O3S
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1
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| 1 |
Ki = 1.03 nM
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CP0480628
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Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Leu-Met-NH2
Show/Hide
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C66H102N18O13S
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1
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| 1 |
Ki = 1.1 nM
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CP0372925
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-furan-3-ylmethyl-2-oxo-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-methyl-benzamide
Show/Hide
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C34H39Cl4N5O4
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1
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| 1 |
Ki = 1.1 nM
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CP0483363
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(2-(4-methylpiperazin-1-yl)-5-o-tolylpyrimidin-4-yl)propanamide
Show/Hide
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C29H31F6N5O
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1
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| 1 |
Ki = 1.1 nM
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CP0469253
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(3R,4S)-3-(2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(4-fluorophenyl)-N,N-bis(2-hydroxyethyl)pyrrolidine-1-carboxamide
Show/Hide
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C28H32F7N3O4
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1
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| 1 |
Ki = 1.1 nM
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CP0486850
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(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-N-[(3S,4R)-1-[3,5-bis(trifluoromethyl)benzoyl]-3-phenylpiperidin-4-yl]-N-methylhexanamide
Show/Hide
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C53H66F6N10O6
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1
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| 1 |
Ki = 1.1 nM
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CP0452242
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-(2-hydroxyethylamino)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C26H24ClF6N3O2
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1
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| 1 |
Ki = 1.12 nM
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CP0410099
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(3R,6S)-6-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-N-ethyl-6-phenylpiperidine-3-carboxamide
Show/Hide
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C25H28F6N2O2
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1
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| 1 |
Ki = 1.13 nM
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CP0493083
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N-[6-[bis(2-hydroxyethyl)amino]-4-(2-chlorophenyl)pyridin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide
Show/Hide
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C28H28ClF6N3O3
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1
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| 1 |
Ki = 1.15 nM
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CP0393934
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2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-(2-fluoroethyl)amino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
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C35H36Cl4FN5O5
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1
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| 1 |
Ki = 1.2 nM
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CP0440758
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
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C32H33Cl4N5O3
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1
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| 1 |
Ki = 1.2 nM
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CP0429510
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-hydroxycarbamoylmethoxyimino-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C31H37Cl4N5O5
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1
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| 1 |
Ki = 1.2 nM
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CP0460868
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-methanesulfonylamino-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H43Cl4N5O5S
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1
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| 1 |
Ki = 1.2 nM
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CP0472059
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(3R,4R)-1-[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-phenylpiperidine-4-carboxamide
Show/Hide
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C54H68F6N10O6
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1
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| 1 |
Ki = 1.2 nM
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CP0457108
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2-[2-[4-[(1S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-phenylethyl]piperazin-1-yl]ethoxy]acetic acid
Show/Hide
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C26H30F6N2O4
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1
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| 1 |
Ki = 1.259 nM
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CP0532726
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2-[4-[(1S)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-phenylethyl]piperazin-1-yl]acetic acid
Show/Hide
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C24H26F6N2O3
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1
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| 1 |
Ki = 1.259 nM
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CP0918856
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N-{[3,5-Bis(trifluoromethyl)phenyl]methyl}-2-(4-fluoro-2-methylphenyl)-N-methyl-1-piperazinecarboxamide
Show/Hide
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C22H22F7N3O
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1
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| 1 |
Ki = 1.288 nM
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CP0405287
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2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
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C34H35Cl4N5O5
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1
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| 1 |
Ki = 1.3 nM
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CP0406322
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3,5-Dichloro-N-[(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-((R)-3-methylcarbamoylmethyl-2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H41Cl4N5O4
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1
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| 1 |
Ki = 1.3 nM
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CP0415009
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methyl 2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetate
Show/Hide
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C35H37Cl4N5O5
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1
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| 1 |
Ki = 1.3 nM
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CP0453000
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[1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]-pyrrolidin-1-ylmethanone
Show/Hide
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C26H28F6N2O2
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1
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| 1 |
Ki = 1.3 nM
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CP0538500
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[1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-phenylcyclobutyl]-piperidin-1-ylmethanone
Show/Hide
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C27H30F6N2O2
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1
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| 1 |
Ki = 1.3 nM
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CP0521902
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2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-4-o-tolyl-pyridin-3-yl]-N-methyl-isobutyramide
Show/Hide
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C29H29F6N3O3S
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1
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| 1 |
Ki = 1.3 nM
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CP0505757
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2-hydroxyethyl)(3-hydroxypropyl)amino)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C29H30ClF6N3O3
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1
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| 1 |
Ki = 1.38 nM
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CP0497472
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2'-methyl-5-(4-methyl-piperazin-1-yl)-biphenyl-2-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
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C29H29F6N3O
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1
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| 1 |
Ki = 1.4 nM
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CP0394035
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(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-({[3,5-bis(trifluoromethyl)phenyl]methyl}(methyl)carbamoyl)-2-(1H-indol-3-yl)ethyl]-4-methylpentanamide
Show/Hide
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C55H63F6N9O8
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1
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| 1 |
Ki = 1.4 nM
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CP0487727
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N-[(3R,4S)-1-(4-acetylpiperazine-1-carbonyl)-4-(4-fluorophenyl)pyrrolidin-3-yl]-2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethylpropanamide
Show/Hide
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C30H33F7N4O3
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1
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| 1 |
Ki = 1.4 nM
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CP0088491
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H65F6N9O8
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1
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| 1 |
Ki = 1.4 nM
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CP0404634
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[4-[(3S,4R)-1-[3,5-bis(trifluoromethyl)benzoyl]-3-phenylpiperidin-4-yl]piperazin-1-yl]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C54H64F6N10O6
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1
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| 1 |
Ki = 1.4 nM
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CP0483547
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[[(3S,4R)-1-[3,5-bis(trifluoromethyl)benzoyl]-3-phenylpiperidin-4-yl]-methylamino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C51H59F6N9O6
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1
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| 1 |
Ki = 1.4 nM
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CP0424545
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(3-methyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
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C33H35Cl4N5O3
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1
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| 1 |
Ki = 1.5 nM
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CP0498152
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3,5-Dichloro-N-[2-[(Z)-cyanomethoxyimino]-3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C31H35Cl4N5O3
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1
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| 1 |
Ki = 1.5 nM
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CP0559341
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(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
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C20H17F7N2O2
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1
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| 1 |
Ki = 1.5 nM
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CP0372175
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2R,3S)-3-hydroxy-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C29H28ClF6N3O3
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1
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| 1 |
Ki = 1.58 nM
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CP0520518
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((R)-2-(hydroxymethyl)pyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C29H28ClF6N3O2
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1
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| 1 |
Ki = 1.58 nM
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CP0507571
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1-[1-[2,3-bis(ethenyl)phenyl]-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]ethyl]piperazine
Show/Hide
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C25H26F6N2O
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1
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| 1 |
Ki = 1.585 nM
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CP0535374
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-methylpiperazine
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C22H24F6N2O
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1
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| 1 |
Ki = 1.585 nM
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CP0463980
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(R)-2-[3-(1-{(R)-5-[(3,5-Dichloro-benzoyl)-methyl-amino]-3-(3,4-dichloro-phenyl)-4-[(Z)-methoxyimino]-pentyl}-piperidin-4-yl)-2-oxo-tetrahydro-pyrimidin-1-yl]-3-(4-hydroxy-phenyl)-propionic acid ethyl ester
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C40H47Cl4N5O6
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1
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| 1 |
Ki = 1.6 nM
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CP0454331
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-imidazol-1-yl-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
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C35H42Cl4N6O3
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1
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| 1 |
Ki = 1.6 nM
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CP0442245
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4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)-1-(2-(pyrrolidin-1-yl)ethyl)imidazolidin-2-one
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C25H26F7N3O2
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1
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| 1 |
Ki = 1.6 nM
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CP0382268
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(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-[benzyl(methyl)carbamoyl]-2-(1H-indol-3-yl)ethyl]-4-methylpentanamide
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C53H65N9O8
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1
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| 1 |
Ki = 1.6 nM
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CP0405557
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3,5-dichloro-N-[(2Z)-3-(3,4-dichlorophenyl)-2-(difluoromethoxyimino)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentyl]-N-methylbenzamide
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C30H34Cl4F2N4O3
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1
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| 1 |
Ki = 1.7 nM
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CP0492389
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3,5-Dichloro-N-{3-(3,4-dichloro-phenyl)-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-2-[(Z)-3-pyrazol-1-yl-propoxyimino]-pentyl}-N-methyl-benzamide
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C35H42Cl4N6O3
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1
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| 1 |
Ki = 1.7 nM
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CP0492615
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(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-1-ethyl-4-phenylimidazolidin-2-one
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C22H22F6N2O2
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1
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| 1 |
Ki = 1.7 nM
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CP0449705
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(2-(4-methylpiperazin-1-yl)-5-o-tolylpyridin-4-yl)propanamide
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C30H32F6N4O
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1
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| 1 |
Ki = 1.7 nM
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CP0494657
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-4-(2-methylphenyl)-2-(4-methylpiperazin-1-yl)pyrimidine-5-carboxamide
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C27H27F6N5O
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1
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| 1 |
Ki = 1.7 nM
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CP0372173
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-(3-hydroxypiperidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
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C29H28ClF6N3O2
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1
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| 1 |
Ki = 1.72 nM
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CP0443005
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2-(1-Benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-ethanone
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C33H38Cl2N4O2
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1
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| 1 |
Ki = 1.8 nM
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CP0454770
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2-(1-Benzyl-piperidin-4-ylamino)-1-[(S)-4-(3,5-bis-trifluoromethyl-benzoyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
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C33H32Cl2F6N4O2
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1
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| 1 |
Ki = 1.8 nM
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CP0848700
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Methanesulfonate{3-[1-{[(3,5-dichloro-benzoyl)-methyl-amino]-methyl}-2-(3,4-dichloro-phenyl)-4-(2-oxo-[1,4']bipiperidinyl-1'-yl)-but-(Z)-ylideneaminooxy]-propyl}-trimethyl-ammonium
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C36H51Cl4N5O6S
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1
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| 1 |
Ki = 1.8 nM
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CP0409130
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-(4-{3-[(2-methoxy-ethylcarbamoyl)-methyl]-2-oxo-2,3-dihydro-benzoimidazol-1-yl}-piperidin-1-yl)-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
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C38H44Cl4N6O5
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1
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| 1 |
Ki = 1.9 nM
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CP0461033
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-yl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
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C34H38Cl4N6O3
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1
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| 1 |
Ki = 1.9 nM
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CP0374889
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-2-hydroxy-2-methyl-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H42Cl4N4O4
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1
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| 1 |
Ki = 1.9 nM
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CP0512488
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(3R,4R)-1-[3-[(4S)-4-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-oxo-4,5-dihydro-1H-2-benzazepin-2-yl]propanoyl]-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-phenylpiperidine-4-carboxamide
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C52H61F6N9O6
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1
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| 1 |
Ki = 1.9 nM
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CP0547709
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(2S,3S)-N-[[2-methoxy-5-(1-methylimidazol-2-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
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C23H28N4O
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1
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| 1 |
Ki = 1.995 nM
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CP0529594
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(2S,3S)-N-[[5-[5-(diethylamino)tetrazol-1-yl]-2-methoxyphenyl]methyl]-2-phenylpiperidin-3-amine;dihydrochloride
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C24H35Cl2N7O
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1
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| 1 |
Ki = 1.995 nM
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CP0383171
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2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]ethanol
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C23H26F6N2O2
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1
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| 1 |
Ki = 1.995 nM
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CP0529165
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-(pyridin-2-ylmethyl)piperazine
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C27H27F6N3O
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1
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| 1 |
Ki = 1.995 nM
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CP0541985
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3-fluorophenyl)ethyl]piperazine
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C21H21F7N2O
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1
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| 1 |
Ki = 1.995 nM
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CP0394390
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-{4-[3-(2-methoxy-ethyl)-2-oxo-2,3-dihydro-benzoimidazol-1-yl]-piperidin-1-yl}-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
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C36H41Cl4N5O4
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1
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| 1 |
Ki = 2 nM
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CP0460155
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(6-(4-methylpiperazin-1-yl)-3-o-tolylpyridin-2-yl)propanamide
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C30H32F6N4O
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1
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| 1 |
Ki = 2 nM
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CP0504319
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(3R,5S)-5-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-methyl-5-phenylpyrrolidin-2-one
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C22H21F6NO2
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1
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| 1 |
Ki = 2 nM
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CP0388686
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2-(3,5-bis(trifluoromethyl)phenyl)-N-((3R,4S)-4-(4-fluorophenyl)-1-(4-(methylsulfonyl)piperazine-1-carbonyl)pyrrolidin-3-yl)-N,2-dimethylpropanamide
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C29H33F7N4O4S
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1
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| 1 |
Ki = 2.1 nM
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CP0395002
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-1H-imidazol-4-ylmethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H38Cl4N6O3
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1
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| 1 |
Ki = 2.2 nM
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CP0480659
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-(2-methoxy-ethylcarbamoyl)-methoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C34H43Cl4N5O5
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1
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| 1 |
Ki = 2.2 nM
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CP0076733
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C57H67F6N9O8
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1
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| 1 |
Ki = 2.2 nM
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CP0425066
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(3R,4R)-1-[(3S)-7-amino-3-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]heptanoyl]-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-phenylpiperidine-4-carboxamide
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C55H70F6N10O6
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1
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| 1 |
Ki = 2.2 nM
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CP0405951
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((2-hydroxyethyl)(propyl)amino)pyridin-3-yl)-N,2-dimethylpropanamide
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C29H30ClF6N3O2
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1
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| 1 |
Ki = 2.24 nM
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CP0497498
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((R)-2-(hydroxymethyl)piperidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C30H30ClF6N3O2
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1
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| 1 |
Ki = 2.27 nM
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CP0404001
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3,5-Dichloro-N-{(R)-5-[4-(3-cyanomethyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
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C35H36Cl4N6O3
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1
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| 1 |
Ki = 2.3 nM
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CP0393865
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-thiophen-3-ylmethyl-tetrahydro-pyrimidin-1-yl)-piperidin-1-yl]-pentyl}-N-methyl-benzamide
Show/Hide
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C34H39Cl4N5O3S
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1
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| 1 |
Ki = 2.4 nM
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CP0404588
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N-[(2Z,3R)-5-[4-[3-(2-amino-2-oxoethyl)-2-oxobenzimidazol-1-yl]piperidin-1-yl]-3-(3,4-dichlorophenyl)-2-methoxyiminopentyl]-3,5-dichloro-N-ethylbenzamide
Show/Hide
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C35H38Cl4N6O4
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1
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| 1 |
Ki = 2.4 nM
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CP0410762
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2-[3-[1-[(3R,4Z)-5-[(3,5-dichlorobenzoyl)-ethylamino]-3-(3,4-dichlorophenyl)-4-methoxyiminopentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetic acid
Show/Hide
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C35H37Cl4N5O5
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1
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| 1 |
Ki = 2.4 nM
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CP0462248
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-2-methoxy-ethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C32H40Cl4N4O4
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1
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| 1 |
Ki = 2.4 nM
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CP0496843
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(R)-3-((1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-3-phenylcyclobutanone
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C21H18F6O2
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1
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| 1 |
Ki = 2.4 nM
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CP0441552
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-ethyl-benzamide
Show/Hide
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C33H35Cl4N5O3
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1
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| 1 |
Ki = 2.5 nM
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CP0235708
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-bromophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H64BrF6N9O8
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1
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| 1 |
Ki = 2.5 nM
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CP0520234
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(2S,3S)-N-[[2-methoxy-5-(2-methyltetrazol-5-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
Show/Hide
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C21H26N6O
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1
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| 1 |
Ki = 2.512 nM
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CP0451122
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-butylpiperazine
Show/Hide
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C25H30F6N2O
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1
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| 1 |
Ki = 2.512 nM
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CP0466513
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2-[2-[4-[(1R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-phenylethyl]piperazin-1-yl]ethoxy]acetic acid
Show/Hide
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C26H30F6N2O4
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1
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| 1 |
Ki = 2.512 nM
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CP0522758
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N-[(3R,5S)-5-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-2-oxo-5-phenylpyrrolidin-3-yl]methanesulfonamide
Show/Hide
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C22H22F6N2O4S
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1
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| 1 |
Ki = 2.6 nM
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CP0206722
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-3-(4-fluorophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C57H66F7N9O8
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1
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| 1 |
Ki = 2.6 nM
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CP0452243
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((R)-3-hydroxypyrrolidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C28H26ClF6N3O2
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1
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| 1 |
Ki = 2.62 nM
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CP0439288
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-3-pyridin-2-ylmethyl-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-ethyl-benzamide
Show/Hide
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C39H40Cl4N6O3
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1
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| 1 |
Ki = 2.7 nM
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CP0424721
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(R)-4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
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C19H15F7N2O2
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1
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| 1 |
Ki = 2.7 nM
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CP0436408
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-2-imidazol-1-yl-ethoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C34H40Cl4N6O3
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1
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| 1 |
Ki = 2.8 nM
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CP0547722
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-chlorophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H64ClF6N9O8
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1
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| 1 |
Ki = 2.9 nM
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CP0409129
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-5-[4-(3-ethylcarbamoylmethyl-2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-2-[(Z)-methoxyimino]-pentyl}-N-ethyl-benzamide
Show/Hide
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C37H42Cl4N6O4
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1
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| 1 |
Ki = 3 nM
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CP0421691
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-(2-methoxyethylamino)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C27H26ClF6N3O2
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1
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| 1 |
Ki = 3.05 nM
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CP0424720
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(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-1-isopropyl-4-phenylimidazolidin-2-one
Show/Hide
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C23H24F6N2O2
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1
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| 1 |
Ki = 3.1 nM
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CP0461177
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2-[4-[(1R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-1-phenylethyl]piperazin-1-yl]acetic acid
Show/Hide
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C24H26F6N2O3
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1
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| 1 |
Ki = 3.162 nM
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CP0461845
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1-[2-[(3,5-dichlorophenyl)methoxy]-1-phenylethyl]piperazine
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C19H22Cl2N2O
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1
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| 1 |
Ki = 3.162 nM
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CP0535256
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2-[2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]ethoxy]acetamide
Show/Hide
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C25H29F6N3O3
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1
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| 1 |
Ki = 3.162 nM
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CP0541983
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(3-methylphenyl)ethyl]piperazine
Show/Hide
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C22H24F6N2O
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1
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| 1 |
Ki = 3.162 nM
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CP0466601
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3,5-Dichloro-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-N-(2-fluoro-ethyl)-benzamide
Show/Hide
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C33H34Cl4FN5O3
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1
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| 1 |
Ki = 3.2 nM
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CP0475748
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2-(1-Benzyl-piperidin-4-ylamino)-1-[4-(3,5-dibromo-benzoyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
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C31H32Br2Cl2N4O2
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1
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| 1 |
Ki = 3.2 nM
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CP0506060
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3-[1-{[(3,5-Dichloro-benzoyl)-methyl-amino]-methyl}-2-(3,4-dichloro-phenyl)-4-(2-oxo-[1,4']bipiperidinyl-1'-yl)-but-(Z)-ylideneaminooxy]-propane-1-sulfonic acid
Show/Hide
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C32H40Cl4N4O6S
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1
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| 1 |
Ki = 3.3 nM
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CP0453002
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1-amino-3-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-N,N-dimethyl-3-phenylcyclobutane-1-carboxamide
Show/Hide
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C24H26F6N2O2
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1
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| 1 |
Ki = 3.3 nM
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CP0527917
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(3-o-tolylpyridin-4-yl)propanamide
Show/Hide
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C25H22F6N2O
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1
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| 1 |
Ki = 3.3 nM
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CP0076730
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-iodophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C56H64F6IN9O8
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1
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| 1 |
Ki = 3.3 nM
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CP0507252
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-(ethyl(2-hydroxyethyl)amino)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C28H28ClF6N3O2
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1
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| 1 |
Ki = 3.37 nM
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CP0442547
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(4-o-tolylpyridin-3-yl)propanamide
Show/Hide
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C25H22F6N2O
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1
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| 1 |
Ki = 3.4 nM
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CP0206720
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]-methylamino]-3-phenylpropanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C55H63F6N9O8
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1
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| 1 |
Ki = 3.4 nM
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CP0456835
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-5-(2-methylphenyl)-2-(4-methylpiperazin-1-yl)pyrimidine-4-carboxamide
Show/Hide
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C27H27F6N5O
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1
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| 1 |
Ki = 3.5 nM
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CP0494667
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(R)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-(4-fluorophenyl)-1-methylimidazolidin-2-one
Show/Hide
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C21H19F7N2O2
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1
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| 1 |
Ki = 3.6 nM
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CP0475001
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(2R)-N-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine-1-carboxamide
Show/Hide
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C23H24F7N3O
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1
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| 1 |
Ki = 3.715 nM
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CP0494658
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-(2-methylphenyl)pyridine-2-carboxamide
Show/Hide
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C23H18F6N2O
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1
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| 1 |
Ki = 3.8 nM
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CP0445400
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2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butylamino]-acetamide
Show/Hide
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C33H35Cl2F6N3O3
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1
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| 1 |
Ki = 4 nM
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CP0371766
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2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(3-o-tolylpyridin-2-yl)propanamide
Show/Hide
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C25H22F6N2O
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1
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| 1 |
Ki = 4 nM
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CP0554284
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4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
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C19H15F7N2O2
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1
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| 1 |
Ki = 4.5 nM
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CP0371767
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-(2-methylphenyl)pyridine-4-carboxamide
Show/Hide
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C23H18F6N2O
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1
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| 1 |
Ki = 4.6 nM
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CP0182738
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C30H36Cl4N4O3
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1
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| 1 |
Ki = 4.7 nM
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CP0403520
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methyl 2-[(Z)-[1-[(3,5-dichlorobenzoyl)-methylamino]-3-(3,4-dichlorophenyl)-5-[4-(2-oxopiperidin-1-yl)piperidin-1-yl]pentan-2-ylidene]amino]oxyacetate
Show/Hide
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C32H38Cl4N4O5
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1
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| 1 |
Ki = 4.7 nM
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CP0343064
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2-[(1S,2S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butylamino]-acetamide
Show/Hide
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C33H35Cl2F6N3O3
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1
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| 1 |
Ki = 5 nM
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CP0455345
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1-[2-[(3,5-dibromophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
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C19H22Br2N2O
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1
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| 1 |
Ki = 5.012 nM
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CP0403575
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1'-[3,5-bis(trifluoromethyl)benzoyl]-2-methylsulfonyl-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C26H23F6N3O5S
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1
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| 1 |
Ki = 5.129 nM
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CP0448954
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2-(1-Benzyl-piperidin-4-ylamino)-1-[4-(3,5-bis-trifluoromethyl-benzoyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
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C33H32Cl2F6N4O2
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1
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| 1 |
Ki = 5.3 nM
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CP0058300
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(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]acetyl]amino]-3-(4-fluorophenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[3,5-bis(trifluoromethyl)phenyl]methylamino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C54H60F7N9O8
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1
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| 1 |
Ki = 5.6 nM
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CP0518037
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(R)-4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-phenylimidazolidin-2-one
Show/Hide
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C19H16F6N2O2
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1
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| 1 |
Ki = 6 nM
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CP0502528
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-3-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-2-carboxamide
Show/Hide
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C28H28F6N4O
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1
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| 1 |
Ki = 6.2 nM
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CP0462786
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4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)-1-(tetrahydro-2H-pyran-4-yl)imidazolidin-2-one
Show/Hide
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C24H23F7N2O3
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1
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| 1 |
Ki = 6.3 nM
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CP0410502
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-[4-(2H-tetrazol-5-yl)butyl]piperazine
Show/Hide
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C26H30F6N6O
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1
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| 1 |
Ki = 6.31 nM
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CP0462244
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-(2-methoxy-ethyl)-oxime
Show/Hide
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C34H36Cl2F6N2O4
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1
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| 1 |
Ki = 7 nM
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CP0391536
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2-(1-Benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-4-(3,5-dimethoxy-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
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C33H38Cl2N4O4
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1
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| 1 |
Ki = 7.1 nM
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CP0455400
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3,5-Dichloro-N-[3-(3,4-dichloro-phenyl)-2-[(Z)-3-methylsulfanyl-propoxyimino]-5-(2-oxo-[1,4']bipiperidinyl-1'-yl)-pentyl]-N-methyl-benzamide
Show/Hide
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C33H42Cl4N4O3S
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1
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| 1 |
Ki = 7.4 nM
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CP0461020
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2-(1-Benzyl-piperidin-4-ylamino)-1-[4-(3,5-dichloro-benzoyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
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C31H32Cl4N4O2
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1
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| 1 |
Ki = 7.7 nM
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CP0403835
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2-[4-[(1S)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]acetamide
Show/Hide
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C23H25F6N3O2
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1
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| 1 |
Ki = 7.943 nM
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CP0429285
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1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-thiophen-2-ylethyl]piperazine
Show/Hide
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C19H20F6N2OS
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1
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| 1 |
Ki = 7.943 nM
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CP0535250
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2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]acetonitrile
Show/Hide
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C23H23F6N3O
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1
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| 1 |
Ki = 7.943 nM
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CP0462247
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2-[(Z)-[1-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenylpiperidin-1-yl)pentan-2-ylidene]amino]oxyacetic acid
Show/Hide
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C33H32Cl2F6N2O5
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1
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| 1 |
Ki = 8 nM
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CP0910933
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2-(R)-4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-(R)-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide
Show/Hide
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C25H28F7N3O3
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1
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| 1 |
Ki = 8.128 nM
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CP0483041
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1'-[3,5-bis(trifluoromethyl)benzoyl]-2-(2-morpholin-4-ylacetyl)-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C31H30F6N4O5
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1
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| 1 |
Ki = 8.318 nM
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CP0524618
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-4-(2-methylphenyl)pyridine-3-carboxamide
Show/Hide
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C23H18F6N2O
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1
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| 1 |
Ki = 8.5 nM
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CP0494644
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-(4-fluoro-2-methylphenyl)-N-methylpiperazine-2-carboxamide
Show/Hide
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C22H22F7N3O
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1
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| 1 |
Ki = 8.71 nM
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CP0429358
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2-[(1R,2R)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-butylamino]-acetamide
Show/Hide
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C33H35Cl2F6N3O3
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1
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| 1 |
Ki = 9 nM
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CP0407303
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5-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]pentanoic acid
Show/Hide
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C26H30F6N2O3
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1
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| 1 |
Ki = 10 nM
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CP0461145
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2-[4-[(1R)-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]acetamide
Show/Hide
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C23H25F6N3O2
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1
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| 1 |
Ki = 10 nM
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CP0391449
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(R)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-3-phenyl-propan-1-one
Show/Hide
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C35H41Cl2N5O3
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1
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| 1 |
Ki = 11 nM
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CP0504349
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2-(3,5-bis(trifluoromethyl)phenyl)-N-(4-(2-chlorophenyl)-6-((S)-2-(hydroxymethyl)piperidin-1-yl)pyridin-3-yl)-N,2-dimethylpropanamide
Show/Hide
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C30H30ClF6N3O2
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1
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| 1 |
Ki = 11.1 nM
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CP0420442
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2-[Bis-(4-hydroxy-4-phenyl-piperidin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-phenyl-piperazin-1-yl]-ethanone
Show/Hide
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C43H47F6N5O3
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1
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| 1 |
Ki = 13 nM
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CP0440564
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(2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-(benzylcarbamoyl)-2-(1H-indol-3-yl)ethyl]-4-methylpentanamide
Show/Hide
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C52H63N9O8
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1
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| 1 |
Ki = 14 nM
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CP0467600
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N-[4-[[4-[[2-[(2R)-2-(3,4-dichlorophenyl)-4-(3,5-dimethylbenzoyl)piperazin-1-yl]-2-oxoethyl]amino]piperidin-1-yl]methyl]phenyl]acetamide
Show/Hide
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C35H41Cl2N5O3
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1
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| 1 |
Ki = 15 nM
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CP0449534
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-cyano-oxime
Show/Hide
|
C32H29Cl2F6N3O3
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1
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| 1 |
Ki = 15 nM
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CP0504173
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one
Show/Hide
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C31H29Cl2F6NO3
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1
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| 1 |
Ki = 15 nM
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CP0960856
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1-((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methylene)-2-(3,5-dichloropyridin-4-yl)hydrazine
Show/Hide
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C16H10Cl4N4O
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1
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| 1 |
Ki = 15 nM
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CP0448120
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1-[2-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazine
Show/Hide
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C21H22F6N2O
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1
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| 1 |
Ki = 15.85 nM
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CP0448411
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3-[[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
Show/Hide
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C24H25F6N5O2
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1
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| 1 |
Ki = 15.85 nM
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CP0448897
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2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]acetic acid
Show/Hide
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C23H24F6N2O3
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1
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| 1 |
Ki = 15.85 nM
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CP0453375
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2-[2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]ethoxy]acetic acid
Show/Hide
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C25H28F6N2O4
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1
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| 1 |
Ki = 15.85 nM
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CP0461197
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4-[2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]ethyl]morpholine
Show/Hide
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C27H33F6N3O2
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1
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| 1 |
Ki = 15.85 nM
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CP0448559
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2-[N'-(1-Benzyl-piperidin-4-yl)-N-(amino-1-Benzyl-piperidin-4-yl)-hydrazino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-phenyl-piperazin-1-yl]-ethanone
Show/Hide
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C45H53F6N7O
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1
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| 1 |
Ki = 17 nM
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CP0424175
|
2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-but-(Z)-ylideneaminooxy]-N-hydroxy-acetamidine
Show/Hide
|
C33H34Cl2F6N4O4
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1
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| 1 |
Ki = 17 nM
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CP0539593
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2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-but-(Z)-ylideneaminooxy]-acetamide
Show/Hide
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C33H33Cl2F6N3O4
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1
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| 1 |
Ki = 17 nM
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CP0371769
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2'-methyl-biphenyl-2-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
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C24H19F6NO
|
1
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| 1 |
Ki = 17 nM
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CP0511923
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(2R)-N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(4-fluoro-2-methylphenyl)-N-methylpiperazine-1-carboxamide
Show/Hide
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C22H22F7N3O
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1
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| 1 |
Ki = 18.2 nM
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CP0465016
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4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazine-1-carboxamide
Show/Hide
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C22H23F6N3O2
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1
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| 1 |
Ki = 19.95 nM
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CP0449214
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(R)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methyl-oxime
Show/Hide
|
C32H32Cl2F6N2O3
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1
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| 1 |
Ki = 20 nM
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CP0406712
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-(2-hydroxy-ethyl)-oxime
Show/Hide
|
C33H34Cl2F6N2O4
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1
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| 1 |
Ki = 20 nM
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CP0463616
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(S)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-3-phenyl-propan-1-one
Show/Hide
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C35H41Cl2N5O3
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1
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| 1 |
Ki = 21 nM
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CP0525511
|
2'-chloro-biphenyl-2-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
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C23H16ClF6NO
|
1
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| 1 |
Ki = 22 nM
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CP0464949
|
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-MePhe(pBz)-Trp-NH2
Show/Hide
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C93H123N19O15S
|
1
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| 1 |
Ki = 23 nM
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CP0382959
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2-(1-Benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-4-(3,5-difluoro-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C31H32Cl2F2N4O2
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1
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| 1 |
Ki = 23 nM
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CP0864130
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one oxime
Show/Hide
|
C31H30Cl2F6N2O3
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1
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| 1 |
Ki = 24 nM
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CP0393024
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2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2-(3,4-dichloro-phenyl)-4-(4-hydroxy-4-phenyl-piperidin-1-yl)-but-(Z)-ylideneaminooxy]-N-methyl-acetamide
Show/Hide
|
C34H35Cl2F6N3O4
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1
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| 1 |
Ki = 24 nM
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CP0038908
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1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methyl-oxime
Show/Hide
|
C32H32Cl2F6N2O3
|
1
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| 1 |
Ki = 25 nM
|
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CP0044049
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methyl-oxime
Show/Hide
|
C32H32Cl2F6N2O3
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1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0454641
|
2-(1-Benzyl-piperidin-4-ylamino)-1-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C33H38Cl2N4O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0392965
|
methyl 2-[(Z)-[1-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-3-(3,4-dichlorophenyl)-5-(4-hydroxy-4-phenylpiperidin-1-yl)pentan-2-ylidene]amino]oxyacetate
Show/Hide
|
C34H34Cl2F6N2O5
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0520610
|
1-[5-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-4-methoxyamino-pentyl]-4-phenyl-piperidin-4-ol
Show/Hide
|
C32H34Cl2F6N2O3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0460573
|
2-[Bis-(4-benzyl-piperazin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C43H47Cl2F6N7O
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0408585
|
2-[N'-(1-Benzyl-piperidin-4-yl)-N-(amino-1-Benzyl-piperidin-4-yl)-hydrazino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-(3,4-chloro)-phenyl-piperazin-1-yl]-ethanone
Show/Hide
|
C45H51Cl2F6N7O
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0460512
|
2-[3,5-bis(trifluoromethyl)benzoyl]-1'-(2,5-dimethoxyphenyl)sulfonyl-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
|
C33H29F6N3O7S
|
1
|
| 1 |
Ki = 30.2 nM
|
|
|
|
CP0540296
|
2-[3,5-bis(trifluoromethyl)benzoyl]-1'-[(3-oxo-4H-1,4-benzoxazin-6-yl)sulfonyl]-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
|
C33H26F6N4O7S
|
1
|
| 1 |
Ki = 30.9 nM
|
|
|
|
CP0448525
|
1-[1-[3,4-bis(ethenyl)phenyl]-2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]ethyl]piperazine
Show/Hide
|
C25H26F6N2O
|
1
|
| 1 |
Ki = 31.62 nM
|
|
|
|
CP0421430
|
2-[Bis-(4-hydroxy-4-phenyl-piperidin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C43H45Cl2F6N5O3
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0468088
|
(R)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-3-(4-hydroxy-phenyl)-propan-1-one
Show/Hide
|
C35H41Cl2N5O4
|
1
|
| 1 |
Ki = 32 nM
|
|
|
|
CP0403711
|
(S)-1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methyl-oxime
Show/Hide
|
C32H32Cl2F6N2O3
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0392966
|
1-[(Z)-4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-3-(3,4-dichloro-phenyl)-5-methoxy-pent-4-enyl]-4-phenyl-piperidin-4-ol
Show/Hide
|
C33H33Cl2F6NO3
|
1
|
| 1 |
Ki = 33 nM
|
|
|
|
CP0879036
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one oxime
Show/Hide
|
C31H30Cl2F6N2O3
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0402236
|
1-[(R)-2-(3,4-Dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-[1-(1H-pyrrol-3-ylmethyl)-piperidin-4-ylamino]-ethanone
Show/Hide
|
C31H37Cl2N5O2
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0257146
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-(2-methylpropyl)amino]-2-oxoethyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C42H52F6N8O5
|
1
|
| 1 |
Ki = 35 nM
|
|
|
|
CP0467833
|
2-[Bis-(4-benzyl-piperidin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-phenyl-piperazin-1-yl]-ethanone
Show/Hide
|
C45H51F6N5O
|
1
|
| 1 |
Ki = 37 nM
|
|
|
|
CP0947437
|
1-[5-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-4-(dimethyl-hydrazono)-pentyl]-4-phenyl-piperidin-4-ol
Show/Hide
|
C33H35Cl2F6N3O2
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0373006
|
1'-[3,5-bis(trifluoromethyl)benzoyl]-2-methyl-5-naphthalen-2-ylsulfonylspiro[6,6a-dihydro-3aH-pyrrolo[3,4-c]pyrrole-4,4'-piperidine]-1,3-dione
Show/Hide
|
C30H25F6N3O5S
|
1
|
| 1 |
Ki = 38.9 nM
|
|
|
|
CP0535063
|
methyl 2-[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]acetate
Show/Hide
|
C24H26F6N2O3
|
1
|
| 1 |
Ki = 39.81 nM
|
|
|
|
CP0492616
|
(S)-4-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-phenylimidazolidin-2-one
Show/Hide
|
C20H18F6N2O2
|
1
|
| 1 |
Ki = 41 nM
|
|
|
|
CP0383021
|
(S)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-2-phenyl-ethanone
Show/Hide
|
C34H39Cl2N5O3
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0441820
|
2'-bromo-biphenyl-2-carboxylic acid (3,5-bis-trifluoromethyl-benzyl)-methyl-amide
Show/Hide
|
C23H16BrF6NO
|
1
|
| 1 |
Ki = 45 nM
|
|
|
|
CP0539513
|
3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-(3-methylphenyl)-2,4-dioxo-1,3,8-triazaspiro[4.5]decane-8-carboxamide
Show/Hide
|
C24H22F6N4O3
|
1
|
| 1 |
Ki = 45.71 nM
|
|
|
|
CP0402234
|
2-(1-Benzyl-piperidin-4-ylamino)-1-[(R)-4-(3,5-bis-trifluoromethyl-benzoyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C33H32Cl2F6N4O2
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0443004
|
2-[Bis-(4-benzyl-piperazin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-phenyl-piperazin-1-yl]-ethanone
Show/Hide
|
C43H49F6N7O
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0492773
|
N-[1-[(4-acetamido-4-phenylpiperidin-1-yl)-[2-[4-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-phenylpiperazin-1-yl]-2-oxoethyl]amino]-4-phenylpiperidin-4-yl]acetamide
Show/Hide
|
C47H53F6N7O3
|
1
|
| 1 |
Ki = 48 nM
|
|
|
|
CP0382341
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-methoxymethyl-oxime
Show/Hide
|
C33H34Cl2F6N2O4
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0916519
|
N-[1-(2'-bromo-biphenyl-2-yl)-methylidene]-N'-(3,5-dichloro-pyridin-4-yl)-hydrazine
Show/Hide
|
C18H12BrCl2N3
|
1
|
| 1 |
Ki = 49 nM
|
|
|
|
CP0518018
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-2-phenylbenzamide
Show/Hide
|
C23H17F6NO
|
1
|
| 1 |
Ki = 51 nM
|
|
|
|
CP0421447
|
N-[4-[[4-[[2-[(2R)-2-(3,4-dichlorophenyl)-4-(3,5-dimethylbenzoyl)piperazin-1-yl]-2-oxoethyl]amino]piperidin-1-yl]methyl]-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C32H38Cl2N6O3S
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0380290
|
(3S)-4-[(2S)-2-[[(2S)-4-amino-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[(5S)-7-[(2S)-1-[[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1,4-dioxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-4-oxo-3-[[(2S)-2-(pyrrolidine-2-carbonylamino)propanoyl]amino]butanoic acid
Show/Hide
|
C69H93N15O15
|
1
|
| 1 |
Ki = 56 nM
|
|
|
|
CP0392967
|
1-[(Z)-4-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-3-(3,4-dichloro-phenyl)-hept-4-enyl]-4-phenyl-piperidin-4-ol
Show/Hide
|
C34H35Cl2F6NO2
|
1
|
| 1 |
Ki = 57 nM
|
|
|
|
CP0448410
|
ethyl 4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazine-1-carboxylate
Show/Hide
|
C24H26F6N2O3
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0555241
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-(2H-tetrazol-5-ylmethyl)piperazine
Show/Hide
|
C23H24F6N6O
|
1
|
| 1 |
Ki = 63.1 nM
|
|
|
|
CP0435416
|
2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-(2-phenylphenyl)propanamide
Show/Hide
|
C25H21F6NO
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0468097
|
(R)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-3-(1H-indol-3-yl)-propan-1-one
Show/Hide
|
C37H42Cl2N6O3
|
1
|
| 1 |
Ki = 70 nM
|
|
|
|
CP0409859
|
3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-8-(2-naphthalen-1-ylethylsulfonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C28H25F6N3O4S
|
1
|
| 1 |
Ki = 74.13 nM
|
|
|
|
CP0409718
|
2-[3,5-bis(trifluoromethyl)benzoyl]-1'-[(3,5-dimethyl-1,2-oxazol-4-yl)sulfonyl]-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
|
C30H26F6N4O6S
|
1
|
| 1 |
Ki = 75.86 nM
|
|
|
|
CP0523823
|
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-Pro(trans-CH2-C6H5)-Trp-NH2
Show/Hide
|
C78H105N19O13
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0373011
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-ethyl-oxime
Show/Hide
|
C33H34Cl2F6N2O3
|
1
|
| 1 |
Ki = 81 nM
|
|
|
|
CP0449713
|
(S)-4-((3,5-bis(trifluoromethyl)benzyloxy)methyl)-4-(4-fluorophenyl)imidazolidin-2-one
Show/Hide
|
C19H15F7N2O2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0402235
|
1-[(R)-2-(3,4-Dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-[1-(1H-imidazol-2-ylmethyl)-piperidin-4-ylamino]-ethanone
Show/Hide
|
C30H36Cl2N6O2
|
1
|
| 1 |
Ki = 92 nM
|
|
|
|
CP0460916
|
1-[4-Benzoyl-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-2-(1-benzyl-piperidin-4-ylamino)-ethanone
Show/Hide
|
C31H34Cl2N4O2
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0453696
|
(R)-4-(((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-4-phenylimidazolidin-2-one
Show/Hide
|
C20H18F6N2O2
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0844754
|
N-[1-(2',6'-dichloro-biphenyl-2-yl)-methylidene]-N'-(3,5-dichloro-pyridin-4-yl)-hydrazine
Show/Hide
|
C18H11Cl4N3
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0503716
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-allyl-oxime
Show/Hide
|
C34H34Cl2F6N2O3
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0553138
|
1-[2-[(3,4-dichlorophenyl)methoxy]-1-phenylethyl]piperazine
Show/Hide
|
C19H22Cl2N2O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0382269
|
C-terminal modified bifunctional peptide, 2
Show/Hide
|
C52H62N8O9
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0401361
|
1-(3,5-Bis-trifluoromethyl-benzyloxy)-3-(3,4-dichloro-phenyl)-5-(4-hydroxy-4-phenyl-piperidin-1-yl)-pentan-2-one O-(2-dimethylamino-ethyl)-oxime
Show/Hide
|
C35H39Cl2F6N3O3
|
1
|
| 1 |
Ki = 103 nM
|
|
|
|
CP0377655
|
3-[[3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl]methyl]benzonitrile
Show/Hide
|
C24H20F6N4O2
|
1
|
| 1 |
Ki = 107.15 nM
|
|
|
|
CP0376481
|
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Pro-MePhe-Trp-NH2
Show/Hide
|
C76H103N19O13
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0437492
|
2-[Bis-(4-benzyl-piperidin-1-yl)-amino]-1-[4-(3,5-bis-trifluoromethyl-benzyl)-2-(3,4-dichloro-phenyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C45H49Cl2F6N5O
|
1
|
| 1 |
Ki = 110 nM
|
|
|
|
CP0437462
|
2-(1-Benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-4-(3,4,5-trimethoxy-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
|
C34H40Cl2N4O5
|
1
|
| 1 |
Ki = 112 nM
|
|
|
|
CP0466511
|
1-[1-phenyl-2-[(3,4,5-trimethoxyphenyl)methoxy]ethyl]piperazine
Show/Hide
|
C22H30N2O4
|
1
|
| 1 |
Ki = 125.89 nM
|
|
|
|
CP0403930
|
8-[3,5-bis(trifluoromethyl)benzoyl]-3-(4-methylsulfanylphenyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C23H19F6N3O3S
|
1
|
| 1 |
Ki = 131.83 nM
|
|
|
|
CP0494945
|
2-(1-Benzyl-piperidin-4-ylamino)-1-(4-methyl-2-phenyl-piperazin-1-yl)-ethanone
Show/Hide
|
C25H34N4O
|
1
|
| 1 |
Ki = 135 nM
|
|
|
|
CP0463410
|
2-(1-Benzyl-piperidin-4-ylamino)-1-{4-[2-(3,5-bis-trifluoromethyl-phenyl)-acetyl]-2-phenyl-piperazin-1-yl}-ethanone
Show/Hide
|
C34H36F6N4O2
|
1
|
| 1 |
Ki = 136 nM
|
|
|
|
CP0515169
|
8-[3,5-bis(trifluoromethyl)benzoyl]-3-[(3-phenylphenyl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C29H23F6N3O3
|
1
|
| 1 |
Ki = 138.04 nM
|
|
|
|
CP0465324
|
(R)-2-Amino-1-(4-{2-[(R)-2-(3,4-dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-oxo-ethylamino}-piperidin-1-yl)-2-phenyl-ethanone
Show/Hide
|
C34H39Cl2N5O3
|
1
|
| 1 |
Ki = 143 nM
|
|
|
|
CP0377741
|
N-[1-[(4-acetamido-4-phenylpiperidin-1-yl)-[2-[4-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(3,4-dichlorophenyl)piperazin-1-yl]-2-oxoethyl]amino]-4-phenylpiperidin-4-yl]acetamide
Show/Hide
|
C47H51Cl2F6N7O3
|
1
|
| 1 |
Ki = 148 nM
|
|
|
|
CP0439286
|
3,5-Dichloro-N-cyclopropyl-N-{(R)-3-(3,4-dichloro-phenyl)-2-[(Z)-methoxyimino]-5-[4-(2-oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidin-1-yl]-pentyl}-benzamide
Show/Hide
|
C34H35Cl4N5O3
|
1
|
| 1 |
Ki = 157 nM
|
|
|
|
CP0449230
|
1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-(furan-2-yl)ethyl]piperazine
Show/Hide
|
C19H20F6N2O2
|
1
|
| 1 |
Ki = 158.49 nM
|
|
|
|
CP0881033
|
N-[1-(2'-chloro-biphenyl-2-yl)-methylidene]-N'-(3,5-dichloro-pyridin-4-yl)-hydrazine
Show/Hide
|
C18H12Cl3N3
|
1
|
| 1 |
Ki = 174 nM
|
|
|
|
CP0382974
|
1-[(R)-2-(3,4-Dichloro-phenyl)-4-(3,5-dimethyl-benzoyl)-piperazin-1-yl]-2-(piperidin-4-ylamino)-ethanone
Show/Hide
|
C26H32Cl2N4O2
|
1
|
| 1 |
Ki = 215 nM
|
|
|
|
CP0497473
|
2-(3,5-bis-trifluoromethyl-benzyloxymethyl)-biphenyl
Show/Hide
|
C22H16F6O
|
1
|
| 1 |
Ki = 224 nM
|
|
|
|
CP0515170
|
3-(1,3-benzodioxol-5-ylmethyl)-8-[3,5-bis(trifluoromethyl)benzoyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C24H19F6N3O5
|
1
|
| 1 |
Ki = 245.47 nM
|
|
|
|
CP0467623
|
2-benzyl-1-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine
Show/Hide
|
C38H40F6N2O4
|
1
|
| 1 |
Ki = 251.19 nM
|
|
|
|
CP0500893
|
5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1'-methylsulfonyl-2-(naphthalene-2-carbonyl)spiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C31H27F6N3O5S
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1
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| 1 |
Ki = 263.03 nM
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CP0435417
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N-[2-[3,5-bis(trifluoromethyl)phenyl]propan-2-yl]-N-methyl-2-phenylbenzamide
Show/Hide
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C25H21F6NO
|
1
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| 1 |
Ki = 295 nM
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CP0521147
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2-[3,5-bis(trifluoromethyl)benzoyl]-1'-(2,2-dimethylpropanoyl)-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C30H29F6N3O4
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1
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| 1 |
Ki = 302 nM
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CP0389565
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[benzyl(2-methylpropyl)amino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C41H56N8O5
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1
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| 1 |
Ki = 308 nM
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CP0911213
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N-(3,5-dichloro-pyridin-4-yl)-N'-[1-(2'-methyl-biphenyl-2-yl)-methylidene]-hydrazine
Show/Hide
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C19H15Cl2N3
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1
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| 1 |
Ki = 316 nM
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CP0529998
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3-[3,5-bis(trifluoromethyl)phenyl]-8-(2,4,6-trimethylbenzoyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C25H23F6N3O3
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1
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| 1 |
Ki = 323.59 nM
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CP0457168
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3-[3,5-bis(trifluoromethyl)phenyl]-8-(naphthalene-1-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C26H19F6N3O3
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1
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| 1 |
Ki = 338.84 nM
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CP0456836
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-1-(2-phenylphenyl)methanamine
Show/Hide
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C22H17F6N
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1
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| 1 |
Ki = 372 nM
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CP0515168
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1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-methyl-8-(naphthalene-1-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C28H23F6N3O3
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1
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| 1 |
Ki = 457.09 nM
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CP0449213
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5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(3-chloro-1-benzothiophene-2-carbonyl)spiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C28H22ClF6N3O3S
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1
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| 1 |
Ki = 501.19 nM
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CP0448216
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1'-[3,5-bis(trifluoromethyl)benzoyl]-2-methyl-5-(thiophen-2-ylmethyl)spiro[6,6a-dihydro-3aH-pyrrolo[3,4-c]pyrrole-4,4'-piperidine]-1,3-dione
Show/Hide
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C25H23F6N3O3S
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1
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| 1 |
Ki = 512.86 nM
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CP0485960
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2-[3,5-bis(trifluoromethyl)phenyl]-N-methyl-N-(2-phenylphenyl)acetamide
Show/Hide
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C23H17F6NO
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1
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| 1 |
Ki = 562 nM
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CP0383823
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8-[3,5-bis(trifluoromethyl)benzoyl]-3-[2-(1H-indol-3-yl)ethyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C26H22F6N4O3
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1
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| 1 |
Ki = 575.44 nM
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CP0182827
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(3S)-3-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]-3-hydroxybutanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-oxobutanoic acid
Show/Hide
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C50H80N14O14S
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1
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| 1 |
Ki = 630 nM
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CP0470844
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1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-8-(2,6-dichlorobenzoyl)-3-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C24H19Cl2F6N3O3
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1
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| 1 |
Ki = 645.65 nM
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CP0518016
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N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-methyl-1-(2-phenylphenyl)methanamine
Show/Hide
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C23H19F6N
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1
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| 1 |
Ki = 724 nM
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CP0349425
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2-[[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[1-[[2-[[3,5-bis(trifluoromethyl)phenyl]methyl-methylamino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C39H48F6N8O5
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1
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| 1 |
Ki = 734 nM
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CP0381974
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[[3,5-bis(trifluoromethyl)phenyl]methyl-(2-methylpropyl)amino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C43H54F6N8O5
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1
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| 1 |
Ki = 743 nM
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CP0453598
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1'-[3,5-bis(trifluoromethyl)benzoyl]-5-(2-methoxybenzoyl)-2-methylspiro[6,6a-dihydro-3aH-pyrrolo[3,4-c]pyrrole-4,4'-piperidine]-1,3-dione
Show/Hide
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C28H25F6N3O5
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1
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| 1 |
Ki = 794.33 nM
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CP0881032
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N-[1-biphenyl-2-yl-methylidene]-N'-(3,5-dichloro-pyridin-4-yl)-hydrazine
Show/Hide
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C18H13Cl2N3
|
1
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| 1 |
Ki = 933 nM
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CP0178626
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(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[2-[benzyl(2-methylpropyl)amino]-2-oxoethyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
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C40H54N8O5
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1
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| 1 |
Ki = 1020 nM
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CP0406858
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1'-acetyl-2-[3,5-bis(trifluoromethyl)benzoyl]-5-phenylspiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C27H23F6N3O4
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1
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| 1 |
Ki = 1071.52 nM
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CP0074738
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(S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl)-4-phenylpiperidin-4-yl)-N-methylacetamine
Show/Hide
|
C35H41Cl2N3O2
|
1
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| 1 |
Ki = 1300 nM
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CP0371768
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2-[3,5-bis(trifluoromethyl)phenyl]-2-methyl-N-(2-phenylphenyl)propanamide
Show/Hide
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C24H19F6NO
|
1
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| 1 |
Ki = 1380 nM
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CP0535454
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1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-8-(2-fluorobenzoyl)-3-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C24H20F7N3O3
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1
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| 1 |
Ki = 1479.11 nM
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CP0539564
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[2-[benzyl(methyl)amino]-2-oxoethyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C37H48N8O5
|
1
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| 1 |
Ki = 1530 nM
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CP0460132
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1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-8-[2-[3-(3,4-dimethoxyphenyl)-4-oxoimidazolidin-1-yl]acetyl]-3-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C30H31F6N5O6
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1
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| 1 |
Ki = 1698.24 nM
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CP0535309
|
8-[3,5-bis(trifluoromethyl)benzoyl]-3-octyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C24H29F6N3O3
|
1
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| 1 |
Ki = 2041.74 nM
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CP0378287
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5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(2-phenylmethoxyacetyl)spiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
|
C28H27F6N3O4
|
1
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| 1 |
Ki = 2290.87 nM
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CP0521146
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1'-acetyl-5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(2-phenylmethoxyacetyl)spiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C30H29F6N3O5
|
1
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| 1 |
Ki = 2344.23 nM
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CP0258730
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[3-[benzyl(methyl)amino]-3-oxopropyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(carbamoylamino)pentanamide
Show/Hide
|
C38H49N7O6
|
1
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| 1 |
Ki = 3000 nM
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CP0395247
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8-[2-(4-benzylpiperidin-1-yl)acetyl]-1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3-methyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
|
C31H34F6N4O3
|
1
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| 1 |
Ki = 3715.35 nM
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CP0454486
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5-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(3,4-dimethoxybenzoyl)spiro[3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrrole-3,4'-piperidine]-4,6-dione
Show/Hide
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C28H27F6N3O5
|
1
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| 1 |
Ki = 4265.8 nM
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CP0451925
|
US10065961, Compound 17
Show/Hide
|
C22H22N6OS2
|
1
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| 1 |
Ki = 6060 nM
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CP0258675
|
(2R)-2-[[(2S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(4S)-2-[2-(benzylamino)-2-oxoethyl]-3-oxo-4,5-dihydro-1H-2-benzazepin-4-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C36H46N8O5
|
1
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| 1 |
Ki = 6190 nM
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CP0490064
|
N-[2-[3,5-bis(trifluoromethyl)phenyl]propan-2-yl]-2-phenylbenzamide
Show/Hide
|
C24H19F6NO
|
1
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| 1 |
Ki > 10000 nM
|
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CP0518017
|
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-phenylbenzamide
Show/Hide
|
C22H15F6NO
|
1
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| 1 |
Ki > 10000 nM
|
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CP0074735
|
[(8R)-8-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C20H18N6O2S
|
1
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| 1 |
Ki > 10000 nM
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CP0088852
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[3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C20H17N5OS2
|
1
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| 1 |
Ki > 10000 nM
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CP0494938
|
US10065961, Compound 11
Show/Hide
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C21H19N5O2S
|
1
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| 1 |
Ki > 10000 nM
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CP0512585
|
US10065961, Compound 31
Show/Hide
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C22H19N5O2S
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1
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| 1 |
Ki > 10000 nM
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CP0404992
|
US10030025, Compound 1
Show/Hide
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C16H14Cl2N6OS
|
1
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| 1 |
Ki = 10300 nM
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CP0088854
|
[(8R)-8-methyl-3-(2-methyl-1,3-thiazol-4-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C21H19N5OS2
|
1
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| 1 |
Ki = 12700 nM
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CP0058622
|
2-[[2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[1-[[2-[benzyl(methyl)amino]-2-oxoethyl]-methylamino]-1-oxo-3-phenylpropan-2-yl]-5-(diaminomethylideneamino)pentanamide
Show/Hide
|
C37H50N8O5
|
1
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| 1 |
Ki = 16050 nM
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CP0088851
|
[(8R)-8-methyl-3-(6-methylpyridin-2-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-(4-thiophen-2-ylphenyl)methanone
Show/Hide
|
C23H21N5OS
|
1
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| 1 |
Ki = 17200 nM
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CP0475416
|
US10030025, Compound 4
Show/Hide
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C16H14ClFN6OS
|
1
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| 1 |
Ki = 19900 nM
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CP0490120
|
US10030025, Compound 38
Show/Hide
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C16H14Cl2N6OS
|
1
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| 1 |
Ki = 21000 nM
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CP0126108
|
(4-fluorophenyl)-[(8R)-8-(2-hydroxyethyl)-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C17H17FN6O2S
|
1
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| 1 |
Ki = 22000 nM
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CP0477855
|
US10030025, Compound 6
Show/Hide
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C16H14ClFN6OS
|
1
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| 1 |
Ki = 22100 nM
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CP0404974
|
US10030025, Compound 2
Show/Hide
|
C17H17FN6OS
|
1
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| 1 |
Ki = 23800 nM
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CP0112422
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
|
C16H15FN6OS
|
1
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| 1 |
Ki > 30000 nM
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CP0120396
|
(4-fluorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-oxadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
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C16H15FN6O2
|
1
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| 1 |
Ki > 30000 nM
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CP0147959
|
[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-phenylmethanone
Show/Hide
|
C16H16N6OS
|
1
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| 1 |
Ki > 30000 nM
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CP0212153
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(4-chlorophenyl)-[(8R)-8-methyl-3-(3-methyl-1,2,4-thiadiazol-5-yl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]methanone
Show/Hide
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C16H15ClN6OS
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1
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| 1 |
Ki > 30000 nM
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CP0386510
|
US10030025, Compound 35
Show/Hide
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C16H14ClFN6OS
|
1
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| 1 |
Ki > 30000 nM
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CP0386511
|
US10030025, Compound 22
Show/Hide
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C17H17FN6OS
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1
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| 1 |
Ki > 30000 nM
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CP0386533
|
US10030025, Compound 33
Show/Hide
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C16H13F3N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0393348
|
US10030025, Compound 10
Show/Hide
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C16H12F4N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0404896
|
US10030025, Compound 43
Show/Hide
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C17H15F3N6O2
|
1
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| 1 |
Ki > 30000 nM
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CP0404897
|
US10030025, Compound 44
Show/Hide
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C17H14F4N6O2
|
1
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| 1 |
Ki > 30000 nM
|
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CP0404898
|
US10030025, Compound 40
Show/Hide
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C17H17FN6O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0404903
|
US10030025, Compound 16
Show/Hide
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C16H15ClN6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0404994
|
US10030025, Compound 8
Show/Hide
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C16H13F3N6OS
|
1
|
| 1 |
Ki > 30000 nM
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|
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CP0483045
|
US10030025, Compound 45
Show/Hide
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C17H16F2N6O2
|
1
|
| 1 |
Ki > 30000 nM
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|
|
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CP0483047
|
US10030025, Compound 18
Show/Hide
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C16H14F2N6OS
|
1
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| 1 |
Ki > 30000 nM
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|
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CP0483246
|
US10030025, Compound 34
Show/Hide
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C16H13F3N6OS
|
1
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| 1 |
Ki > 30000 nM
|
|
|
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CP0483247
|
US10030025, Compound 15
Show/Hide
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C16H15FN6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0483248
|
US10030025, Compound 27
Show/Hide
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C17H18N6O2S
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0483249
|
US10030025, Compound 32
Show/Hide
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C16H14F2N6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0483250
|
US10030025, Compound 36
Show/Hide
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C16H14ClFN6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0483251
|
US10836768, Cpd no 29
Show/Hide
|
C17H15N7OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0483278
|
US10030025, Compound 42
Show/Hide
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C16H13F3N6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0483288
|
US10030025, Compound 13
Show/Hide
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C17H17FN6O2
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0486297
|
US10030025, Compound 14
Show/Hide
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C16H15FN6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0486298
|
US10030025, Compound 19
Show/Hide
|
C17H18N6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0490119
|
US10030025, Compound 9
Show/Hide
|
C16H14F2N6OS
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
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CP0490121
|
US10030025, Compound 39
Show/Hide
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C17H17FN6OS
|
1
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| 1 |
Ki > 30000 nM
|
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CP0493498
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US10030025, Compound 25
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C17H17FN6O2S
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1
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| 1 |
Ki > 30000 nM
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CP0493499
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US10030025, Compound 17
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C16H14F2N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0495553
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US10030025, Compound 7
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C16H13F3N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0495554
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US10030025, Compound 31
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C16H12F4N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0526117
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US10030025, Compound 21
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C17H15F3N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0536136
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US10030025, Compound 26
Show/Hide
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C17H18N6OS
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1
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| 1 |
Ki > 30000 nM
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CP0544343
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US10030025, Compound 24
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C18H19FN6OS
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1
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| 1 |
Ki > 30000 nM
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CP0493430
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US10030025, Compound 37
Show/Hide
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C16H15ClN6OS
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1
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| 1 |
Ki = 32000 nM
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CP0483048
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US10030025, Compound 30
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C21H20N6O2S
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1
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| 1 |
Ki = 40000 nM
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CP0041194
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(R)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester
Show/Hide
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C25H20N2O3
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1
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| 1 |
Ki > 100000 nM
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CP0044631
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(S)-3-methyl-2-phenyl-N-(1-phenylpropyl)quinoline-4-carboxamide
Show/Hide
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C26H24N2O
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1
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| 1 |
Ki > 100000 nM
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CP0114970
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(S)-(-)-N-(R-ethylbenzyl)-3-hydroxy-2-phenylquinoline-4-carboxamide
Show/Hide
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C25H22N2O2
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1
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| 1 |
Ki > 100000 nM
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CP0325308
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(S)-Phenyl-[(2-phenyl-quinoline-4-carbonyl)-amino]-acetic acid methyl ester
Show/Hide
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C25H20N2O3
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1
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| 1 |
Ki > 100000 nM
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CP0383278
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methyl 2-phenyl-2-[(2-phenylquinoline-4-carbonyl)amino]acetate
Show/Hide
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C25H20N2O3
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1
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| 1 |
Ki > 100000 nM
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CP0394110
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2-Phenyl-quinoline-4-carboxylic acid ((S)-1-phenyl-propyl)-amide
Show/Hide
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C25H22N2O
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1
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| 1 |
Ki > 100000 nM
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CP0373762
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3-Dimethylaminomethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C28H29N3O
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1
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| 1 |
Ki > 100000 nM
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CP0378060
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2-Phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C25H22N2O
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1
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| 1 |
Ki > 100000 nM
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CP0378844
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3-methoxy-2-phenyl-N-[(1S)-1-phenylpropyl]quinoline-4-carboxamide
Show/Hide
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C26H24N2O2
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1
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| 1 |
Ki > 100000 nM
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CP0431498
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2-[2-phenyl-4-[[(1R)-1-phenylpropyl]carbamoyl]quinolin-3-yl]oxyacetic acid
Show/Hide
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C27H24N2O4
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1
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| 1 |
Ki > 100000 nM
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CP0440468
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3-Amino-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C25H23N3O
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1
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| 1 |
Ki > 100000 nM
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CP0453898
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3-Methyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C26H24N2O
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1
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| 1 |
Ki > 100000 nM
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CP0460321
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3-Hydroxy-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C25H22N2O2
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1
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| 1 |
Ki > 100000 nM
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CP0462356
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3-Ethyl-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C27H26N2O
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1
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| 1 |
Ki > 100000 nM
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CP0509985
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3-(2-Hydroxy-ethoxy)-2-phenyl-quinoline-4-carboxylic acid ((R)-1-phenyl-propyl)-amide
Show/Hide
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C27H26N2O3
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1
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| 1 |
Ki > 100000 nM
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CP0402957
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2-(1-Benzyl-piperidin-4-ylamino)-1-{2-(3,4-dichloro-phenyl)-4-[2-(3,4,5-trimethoxy-phenyl)-acetyl]-piperazin-1-yl}-ethanone
Show/Hide
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C35H42Cl2N4O5
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1
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| 1 |
Ki > 1000 nM
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CP0457299
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2-(1-Benzyl-piperidin-4-ylamino)-1-[2-(3,4-dichloro-phenyl)-4-(3,5-dihydroxy-benzoyl)-piperazin-1-yl]-ethanone
Show/Hide
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C31H34Cl2N4O4
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1
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| 1 |
Ki > 1000 nM
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