Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-(5,9-Diphenyl-1,7-dioxa-4-aza-spiro[5.5]undec-4-ylmethyl)-2,4-dihydro-[1,2,4]triazol-3-one
    Show/Hide
 PubChem ID
CID: 135890952
Canonical SMILES
O=c1[nH]nc(CN2CCOC3(CCC(CO3)c3ccccc3)C2c2ccccc2)[nH]1
    Show/Hide
Compound Formula C23H26N4O3
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS