General Information of the Compound
Compound ID
CP0514439
Compound Name
2-[[(2S)-4-(dipentylcarbamoyl)-1-(diphenylcarbamoyl)piperazine-2-carbonyl]amino]acetic acid
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Structure
Formula
C31H43N5O5
Molecular Weight
565.715
Canonical SMILES
CCCCCN(CCCCC)C(=O)N1CCN([C@@H](C1)C(=O)NCC(O)=O)C(=O)N(c1ccccc1)c1ccccc1
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InChI
InChI=1S/C31H43N5O5/c1-3-5-13-19-33(20-14-6-4-2)30(40)34-21-22-35(27(24-34)29(39)32-23-28(37)38)31(41)36(25-15-9-7-10-16-25)26-17-11-8-12-18-26/h7-12,15-18,27H,3-6,13-14,19-24H2,1-2H3,(H,32,39)(H,37,38)/t27-/m0/s1
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InChIKey
MSECWNMVFATCEZ-MHZLTWQESA-N
Physicochemical Property
logP
4.9341
Rotatable Bonds
13
Heavy Atom Count
41
Polar Areas
113.5
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44324531
ChEMBL ID
CHEMBL90035
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01410, Substance-P receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 597 nM
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