Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(2S,3S)-3-(3,5-Bis-trifluoromethyl-benzyloxy)-2-phenyl-piperidin-1-ylmethyl]-2,4-dihydro-[1,2,4]triazole-3-thione
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 PubChem ID
CID: 11800024
SID: 16913471
Canonical SMILES
FC(F)(F)c1cc(CO[C@H]2CCCN(Cc3n[nH]c(=S)[nH]3)[C@H]2c2ccccc2)cc(c1)C(F)(F)F
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Compound Formula C23H22F6N4OS
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.7943 nM