Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-{3-[2-Methoxy-5-(5-trifluoromethyl-tetrazol-1-yl)-phenyl]-6-phenyl-1-oxa-7-aza-spiro[4.5]dec-7-ylmethyl}-2,4-dihydro-[1,2,4]triazol-3-one
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 PubChem ID
CID: 136094863
Canonical SMILES
COc1ccc(cc1[C@H]1COC2(C1)CCCN(Cc1n[nH]c(=O)[nH]1)C2c1ccccc1)-n1nnnc1C(F)(F)F
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Compound Formula C26H27F3N8O3
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.1 nM
   TI
   LI
   LO
   TS