Brief Information of the Compound and Protein
Compound Name
3-(2-Methoxy-phenyl)-6-phenyl-1-oxa-7-aza-spiro[4.5]decane
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PubChem ID
CID: 44325096
Canonical SMILES
COc1ccccc1[C@H]1COC2(C1)CCCNC2c1ccccc1
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Compound Formula C21H25NO2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 6.5 nM
   TI
   LI
   LO
   TS