Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-piperazine-2,3-dione
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 PubChem ID
CID: 15295987
Canonical SMILES
FC(F)(F)c1cc(CN2CC(Cc3c[nH]c4ccccc34)NC(=O)C2=O)cc(c1)C(F)(F)F
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Compound Formula C22H17F6N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS