Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[5-[[5-(4-fluorophenyl)-9-[2-(trifluoromethoxy)phenyl]-1,7-dioxa-4-azaspiro[5.5]undecan-4-yl]methyl]-2H-triazol-4-yl]-N,N-dimethylmethanamine
    Show/Hide
 PubChem ID
CID: 44318672
Canonical SMILES
CN(C)Cc1nn[nH]c1CN1CCOC2(CCC(CO2)c2ccccc2OC(F)(F)F)C1c1ccc(F)cc1
    Show/Hide
Compound Formula C27H31F4N5O3
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.4 nM
   TI
   LI
   LO
   TS