Brief Information of the Compound and Protein
Compound Name
3-[[4-[2-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-phenylethyl]piperazin-1-yl]methyl]-1,4-dihydro-1,2,4-triazol-5-one
    Show/Hide
PubChem ID
CID: 135530616
SID: 15206780
Canonical SMILES
Oc1n[nH]c(CN2CCN(CC2)C(COCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c2ccccc2)n1
    Show/Hide
Compound Formula C24H25F6N5O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 15.85 nM
   TI
   LI
   LO
   TS