Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(3,5-Bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-1-methyl-imidazolidine-2,4-dione
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 PubChem ID
CID: 10073370
SID: 15058810
Canonical SMILES
CN1C(=O)N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(=O)C1Cc1c[nH]c2ccccc12
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Compound Formula C22H17F6N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 153 nM
   TI
   LI
   LO
   TS