Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-(chloromethyl)-N-methyl-4-phenylpyridine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 54582296
Canonical SMILES
CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)c1c(CCl)nccc1-c1ccccc1
    Show/Hide
Compound Formula C23H17ClF6N2O
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 52 nM
   TI
   LI
   LO
   TS