Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-[4-(3,5-Bis-trifluoromethyl-benzyl)-piperazin-2-ylmethyl]-1H-indole
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 PubChem ID
CID: 10411026
SID: 15428639
Canonical SMILES
FC(F)(F)c1cc(CN2CCNC(Cc3c[nH]c4ccccc34)C2)cc(c1)C(F)(F)F
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Compound Formula C22H21F6N3
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 567 nM
   TI
   LI
   LO
   TS