Brief Information of the Compound and Protein
Compound Name
1-Benzyl-3-(3,5-bis-trifluoromethyl-benzyl)-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione
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PubChem ID
CID: 10460069
SID: 15481942
Canonical SMILES
O=C1C(Cc2c[nH]c3ccccc23)N(Cc2ccccc2)C(=O)N1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1
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Compound Formula C28H21F6N3O2
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 310 nM
   TI
   LI
   LO
   TS