Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-2-methyl-6-(4-methylpiperazin-1-yl)-4-phenylpyridine-3-carboxamide
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 PubChem ID
CID: 54585202
Canonical SMILES
CN1CCN(CC1)c1cc(-c2ccccc2)c(C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)c(C)n1
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Compound Formula C27H26F6N4O
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS