Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-trans-4-(((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)(methyl)amino)methyl)-1H-imidazol-2(3H)-one
    Show/Hide
 PubChem ID
CID: 44415392
Canonical SMILES
CN(Cc1c[nH]c(=O)[nH]1)[C@@H]1CC[C@H](OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@H]1c1ccccc1
    Show/Hide
Compound Formula C25H25F6N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2.4 nM
   TI
   LI
   LO
   TS