Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-Benzylidene-3-(3,5-dimethyl-benzyloxy)-1-aza-bicyclo[2.2.2]octane
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 PubChem ID
CID: 11724403
SID: 16829731
Canonical SMILES
Cc1cc(C)cc(COC2C3CCN(CC3)\C2=C\c2ccccc2)c1
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Compound Formula C23H27NO
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
2
IC50 = 129 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 615 nM