Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2S,3S)-N-(2-Methoxy-5-(5-(trifluoromethyl)-1H-tetrazol-1-yl)benzyl)-2-phenylpiperidin-3-amine dihydrchloride
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 PubChem ID
CID: 6918330
SID: 12015048
Canonical SMILES
COc1ccc(-n2nnnc2C(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1.Cl.Cl
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Compound Formula C21H25Cl2F3N6O
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.02512 nM
   TI
   LI
   LO
   TS
CL000228 IM-9
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 0.02512 nM
   TI
   LI
   LO
   TS