Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(10S)-3-[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]-10-phenyl-1-oxa-9-azaspiro[4.5]dec-3-ene
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 PubChem ID
CID: 71456209
Canonical SMILES
COc1ccc(cc1C1=CC2(CCCN[C@H]2c2ccccc2)OC1)-n1nnnc1C(F)(F)F
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Compound Formula C23H22F3N5O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.08 nM
   TI
   LI
   LO
   TS