Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3,5-Bis-trifluoromethyl-benzyl)-3-(1H-indol-3-ylmethyl)-piperazine-2,5-dione
    Show/Hide
 PubChem ID
CID: 10027661
SID: 15009264
Canonical SMILES
FC(F)(F)c1cc(CN2CC(=O)NC(Cc3c[nH]c4ccccc34)C2=O)cc(c1)C(F)(F)F
    Show/Hide
Compound Formula C22H17F6N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4333 nM
   TI
   LI
   LO
   TS