Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[2-cyclopropyloxy-5-(trifluoromethoxy)phenyl]methyl]-1-phenyl-6-(2H-tetrazol-5-yl)-8-azabicyclo[3.2.1]octan-2-amine
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 PubChem ID
CID: 44407431
Canonical SMILES
FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3NC2(CC3c2nnn[nH]2)c2ccccc2)c1
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Compound Formula C25H27F3N6O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.65 nM
   TI
   LI
   LO
   TS