Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2S)-5-[3,5-bis(trifluoromethyl)phenyl]-1-(1H-indol-3-yl)-3-oxopentan-2-yl]-2-pyridin-4-ylacetamide
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 PubChem ID
CID: 10098987
SID: 15086391
Canonical SMILES
FC(F)(F)c1cc(CCC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)Cc2ccncc2)cc(c1)C(F)(F)F
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Compound Formula C28H23F6N3O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
3
IC50 = 10 nM
   TI
   LI
   LO
   TS