Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1'-[3,5-bis(trifluoromethyl)benzoyl]-5-(2-methoxybenzoyl)-2-methylspiro[6,6a-dihydro-3aH-pyrrolo[3,4-c]pyrrole-4,4'-piperidine]-1,3-dione
    Show/Hide
 PubChem ID
CID: 44334582
Canonical SMILES
COc1ccccc1C(=O)N1CC2C(C(=O)N(C)C2=O)C11CCN(CC1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
    Show/Hide
Compound Formula C28H25F6N3O5
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 794.33 nM
   TI
   LI
   LO
   TS