Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+) (2-Methoxy-benzyl)-(2-phenyl-piperidin-3-yl)-amine
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 PubChem ID
CID: 5311057
SID: 14775946
Canonical SMILES
COc1ccccc1CN[C@H]1CCCN[C@H]1c1ccccc1
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Compound Formula C19H24N2O
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 0.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.6 nM
   TI
   LI
   LO
   TS
3
Ki = 0.2512 nM
   TI
   LI
   LO
   TS
CL000228 IM-9
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 0.1698 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.2 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.49 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM
2 Ki = 0.17 nM
3 Ki = 0.3981 nM