Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-benzyloxy-2-(4-methoxybenzylamino)-1-[1-methylsulfonylspiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]-1-yl]-1-propanone
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 PubChem ID
CID: 44297492
Canonical SMILES
CN(C)c1ccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CN(c4ccccc34)S(C)(=O)=O)CC2)cc1
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Compound Formula C32H40N4O4S
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS