Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2R)-1-[benzyl(methyl)amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-1-methylsulfanylspiro[2H-indole-3,4'-piperidine]-1'-carboxamide
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 PubChem ID
CID: 71450949
Canonical SMILES
CSN1CC2(CCN(CC2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N(C)Cc2ccccc2)c2ccccc12
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Compound Formula C33H37N5O2S
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 164 nM
   TI
   LI
   LO
   TS