Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-cis-5-((((3-(3,5-bis(trifluoromethyl)benzyloxy)-2-phenylcyclopentyl)methyl)(methyl)amino)methyl)-2H-1,2,4-triazol-3(4H)-one
    Show/Hide
 PubChem ID
CID: 136043853
Canonical SMILES
CN(C[C@H]1CC[C@H](OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)[C@@H]1c1ccccc1)Cc1n[nH]c(=O)[nH]1
    Show/Hide
Compound Formula C25H26F6N4O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 4.7 nM
   TI
   LI
   LO
   TS