Brief Information of the Compound and Protein
Compound Name
2-(3,5-bis(trifluoromethyl)phenyl)-N,2-dimethyl-N-(3-o-tolylpyridin-4-yl)propanamide
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PubChem ID
CID: 22000062
Canonical SMILES
CN(C(=O)C(C)(C)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1ccncc1-c1ccccc1C
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Compound Formula C25H22F6N2O
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 3.3 nM
   TI
   LI
   LO
   TS