Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(S)-1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-acetamide
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 PubChem ID
CID: 44299271
Canonical SMILES
NC(=O)CN[C@H](COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(c1ccccc1)c1ccccc1
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Compound Formula C26H24F6N2O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 0.53 nM
   TI
   LI
   LO
   TS
2
Ki = 0.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5248 nM